Abstract: The present invention relates to a novel promoter for regulating ADH gene expression in an organic acid-resistant yeast, and a method of producing an organic acid by expressing an organic acid production-related gene using the same. When an organic acid production-related target gene is expressed in the organic acid-resistant yeast using the novel promoter according to the present invention, there is an advantage in that the yeast can produce the organic acid with high efficiency while having resistance to the organic acid without inhibiting the growth ability of the yeast.

Abstract: A cosmetic container includes an outer container, an inner container inserted into the outer container to receive a content injected therein, and a pump support coupled to an upper opening of the inner container and including a support body connecting to an inside of the inner container. The container further includes a pump inserted through the support body to discharge the content, and a shoulder coupled to an upper portion of the outer container to downwardly press the pump support with respect to the outer container.

Abstract: Disclosed is a mixing container capable of mixing and discharging two different types of contents. The mixing container according to one aspect of the present invention comprises: a main body part having an inner space therein; a rotating part rotatably coupled to one end of the main body part; a moving part that is screwed to the rotating part and can move linearly by means of rotation of the rotating part in the inner space; and a pressing part that is provided in the main body part and is elastically deformed by an external force so as to reduce the volume of the inner space, wherein the inner space is divided, by the moving part, into a first space filled with a first content and a second space filled with a second content, the first space and the second space communicate with each other by means of movement of the moving part such that the first content and the second content can be mixed, and the mixed contents are discharged by means of elastic deformation of the pressing part.

Abstract: Disclosed is a discharge container capable of discharging different types of content. A discharge container according to one aspect of the present invention comprises: a first container which includes therein an insertion space and a first inner space separated from the insertion space by a partition wall; a second container which is formed separately from the first container and inserted into the insertion space, and which is provided with a second inner space; a first pump module which is coupled to the first container and discharges first content filled into the first inner space; and a second pump module which is coupled to the first container, becomes inserted into a second space when the second container is inserted into the insertion space, and discharges second content filled into the second inner space.

Abstract: Disclosed is a mixing container for using two types of contents by mixing. A mixing container according to an aspect of the present invention has: a first body having a first inner space; and an insertion head inserted below the first body. The insertion head comprises: a second body which has a center protrusion having a through hole and protruding downward by a fixed length; a piston which forms a second inner space by being movably inserted into the insertion head and closes the through hole by coming into contact with the center protrusion; and a bottom cap which covers the bottom of the second body. The center protrusion is released from the contact with the piston by means of the descent of the piston due to an external force, and thus the first inner space and second inner space communicate.

Abstract: The present invention relates to an acid-resistant yeast endowed with a lactic acid production ability and having a suppressed ethanol production pathway, and a method for producing lactic acid using same. According to the present invention, by effectively suppressing the production of ethanol in an acid-resistant yeast, and by expressing an LDH enzyme with strong expression and high efficiency, it is possible to produce lactic acid with high yield even at low pH without degrading growth.

Abstract: The present invention relates to a synthetic promoter capable of controlling the expression of a target gene at various locations in the genome of an acid-resistant strain, and more particularly to a synthetic promoter including a core promoter derived from an acid-resistant strain and an upstream activating sequence (UAS) element serving as an enhancer. When the present invention is applied to a variety of genetic and metabolic engineering techniques for acid-resistant yeast, various metabolic networks can be configured as desired while controlling the expression level of the target gene, so a method of producing various metabolites using acid-resistant yeast is provided, and the cost of producing the metabolites can be greatly reduced depending on the properties of the acid-resistant yeast.

Abstract: Disclosed is a cosmetic container that allows easy recycling and refilling. A cosmetic container according to one aspect of the invention includes: an outer container; an inner container separably inserted into the outer container and configured to receive a content injected therein; a pump support coupled to an upper opening of the inner container and including a support body connecting to an inside of the inner container; a pump inserted through the support body and configured to discharge the content; and a shoulder separably coupled to an upper portion of the outer container to downwardly press the pump support with respect to the outer container, where separating the shoulder from the outer container may separate the pump from the support body and thereby enable a replacing of the inner container and the pump support.

Abstract: A cosmetic container that grinds and dispenses a content is disclosed. The cosmetic container includes: an inner container having an interior space filled with a content; a dial that is rotatably coupled at an upper part of the inner container and includes a dispensing hole for dispensing the content and a cutter for grinding the content; a screw that is positioned at a lower part of the dial within the interior space and rotates together with the dial; a piston inserted around the screw to ascend and descend within the interior space; and an elastic member that is positioned at a lower part of the piston and pushes the piston upward. The piston is screw-joined with the screw to maintain a particular height, and rotating the dial disengages the screw joint between the piston and the screw to allow the piston to be moved upward by the elastic member.

Abstract: A container for spraying liquid is disclosed, which includes: a tube having a filling space; a body in which the tube is inserted, where the outer perimeter of the tube and the inner perimeter of the body form a body outlet passage, a lower tube hole is formed at a bottom of the tube as an entrance to the body outlet passage, and an upper movement hole is formed at a top of the body as an exit from the body outlet passage; a body cover coupled to the top of the body, where the body cover includes a cover channel connecting with the upper movement hole and a pump insertion space connecting with the cover channel and receiving a pump inserted therein; and a pump support coupled to the top of the body cover and supporting the pump to block outside air from entering the pump insertion space.

Abstract: The present invention relates to: acid-resistant yeast to which lactic acid productivity is imparted, and in which the conversion of pyruvate into acetaldehyde is inhibited and, consequently, the ethanol production pathway is inhibited; and a method for producing lactic acid by using same.

Abstract: Disclosed is a method of producing lactic acid using a recombinant acid-resistant yeast with inhibited lactate metabolism and alcohol production. More specifically, disclosed are a recombinant acid-resistant yeast in which lactate consumption reaction is reduced and which is imparted with lactic-acid-producing ability to thereby exhibit improved lactic-acid-producing ability and reduced ethanol production, and a method of producing lactic acid using the same.

Abstract: Disclosed are a recombinant acid-resistant yeast having improved lactic-acid-producing ability and a method of preparing lactic acid using the same. When producing lactic acid using the recombinant acid-resistant yeast according to the present invention, not only lactic-acid fermentation can be performed with lactic-acid-producing ability similar to that of bacterial fermentation using a remarkably smaller amount of a neutralizing agent than in the case of conventional bacterial fermentation, but also the production of ethanol and glycerol which are byproducts can be reduced. Thus, fermentation costs can be greatly reduced and the cost of subsequent purification processes can be reduced.

Abstract: Disclosed are a recombinant acid-resistant yeast having lactic acid-producing ability and suppressed glycerol production and a method of preparing lactic acid using the same. More particularly, disclosed are a recombinant acid-resistant yeast into which a gene involved in lactic acid production is introduced and in which a gene involved in glycerol production is deleted or attenuated, and a method of preparing lactic acid using the same. When producing lactic acid using the recombinant acid-resistant yeast, the production of lactic acid is maintained while the production of glycerol is reduced, so crosslinking by glycerol can be suppressed in the oligomerization reaction for conversion to lactide, and thus the conversion yield of lactic acid to lactide can be increased.

Abstract: The present invention relates to an acid-resistant yeast endowed with a lactic acid production ability and having a suppressed ethanol production pathway, and a method for producing lactic acid using same. According to the present invention, by effectively suppressing the production of ethanol in an acid-resistant yeast, and by expressing an LDH enzyme with strong expression and high efficiency, it is possible to produce lactic acid with high yield even at low pH without degrading growth.

Abstract: The present invention relates to a novel promoter for regulating ADH gene expression in an organic acid-resistant yeast, and a method of producing an organic acid by expressing an organic acid production-related gene using the same. When an organic acid production-related target gene is expressed in the organic acid-resistant yeast using the novel promoter according to the present invention, there is an advantage in that the yeast can produce the organic acid with high efficiency while having resistance to the organic acid without inhibiting the growth ability of the yeast.

Abstract: An airless eye cream container is proposed. The container includes an airless pump installed to be very suitably used for an eye cream cosmetic container so as to store eye cream cosmetics exclusively to block the introduction of external air or foreign substances and prevent contamination and deterioration of cosmetics, and a predetermined amount of eye cream can be accurately discharged and used by operating the pump in use to not only improve the convenience of use, but also reduce the waste of cosmetics.

Abstract: The present invention relates to a novel compound having an effect of inhibiting platelet aggregation and a salt thereof and, more specifically, to: a novel platelet aggregation inhibitor specifically inhibiting shear stress-induced platelet aggregation; a pharmaceutical composition containing the same as an active ingredient; and a preparation method therefor.

Abstract: The present invention relates to a variable pinhole collimator and a radiographic imaging device using same, in which the variable pinhole collimator includes: a plurality of pinhole plates formed in each plate surface thereof with a plurality of pinhole formation holes having different sizes along a circumferential direction, formed in each plate surface thereof with a plurality of rotation operation holes around the rotation axis along the circumferential direction, and configured to be laminated in an incidence direction of radiation; and a driving module inserted into the rotation operation holes of the plurality of pinhole plates in the incidence direction to rotate the plurality of pinhole plates about the rotation axis, and configured to rotate the plurality of pinhole plates to form a pinhole in the overlapping area. Accordingly, various pinhole shapes can be achieved since it is possible to change parameters constituting a pinhole of the pinhole collimator.

Abstract: The present invention relates to a variable pinhole collimator and a radiographic imaging device using same, in which the variable pinhole collimator includes: a plurality of pinhole plates formed in each plate surface thereof with a plurality of pinhole formation holes having different sizes along a circumferential direction, formed in each plate surface thereof with a plurality of rotation operation holes around the rotation axis along the circumferential direction, and configured to be laminated in an incidence direction of radiation; and a driving module inserted into the rotation operation holes of the plurality of pinhole plates in the incidence direction to rotate the plurality of pinhole plates about the rotation axis, and configured to rotate the plurality of pinhole plates to form a pinhole in the overlapping area. Accordingly, various pinhole shapes can be achieved since it is possible to change parameters constituting a pinhole of the pinhole collimator.