Patents by Inventor Kian-Ngiap Chua

Kian-Ngiap Chua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patient stratification and determining clinical outcome for cancer patients
    Patent number: 9953129
    Abstract: In a first aspect the present invention is directed to a method of generating a scheme allowing classification of a cancer of an individual patient for estimating a clinical outcome for said patient. It also refers to a method of estimating a clinical outcome of a patient suffering from epithelial ovarian cancer (EOC). The present invention also refers to a method of determining whether the epithelial mesenchymal score of a patient suffering from a cancer can be changed by administering an EMT reversal agent to increase patients susceptibility for an anti-cancer treatment.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: April 24, 2018
    Assignees: Agency for Science, Technology and Research, National University of Singapore
    Inventors: Jean Paul Thiery, Yun-Ju Ruby Huang, Kian Ngiap Chua, Wen Jing Sim, Seiichi Mori
  • PATIENT STRATIFICATION AND DETERMINING CLINICAL OUTCOME FOR CANCER PATIENTS
    Publication number: 20140236495
    Abstract: In a first aspect the present invention is directed to a method of generating a scheme allowing classification of a cancer of an individual patient for estimating a clinical outcome for said patient. It also refers to a method of estimating a clinical outcome of a patient suffering from epithelial ovarian cancer (EOC). The present invention also refers to a method of determining whether the epithelial mesenchymal score of a patient suffering from a cancer can be changed by administering an EMT reversal agent to increase patients susceptibility for an anti-cancer treatment.
    Type: Application
    Filed: September 24, 2012
    Publication date: August 21, 2014
    Inventors: Jean Paul Thiery, Yun-Ju Ruby Huang, Kian Ngiap Chua, Wen Jing Sim, Seiichi Mori
  • Compositions and methods for the expansion and differentiation of stem cells
    Patent number: 8361502
    Abstract: The instant invention provides methods and compositions for the expansion and differentiation of stem cells.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: January 29, 2013
    Assignee: The Johns Hopkins University
    Inventors: Hai-Quan Mao, Kam W. Leong, Kian-Ngiap Chua, Seeram Ramakrishna
  • Compositions and methods for the expansion and differentiation of stem cells
    Publication number: 20080153163
    Abstract: The instant invention provides methods and compositions for the expansion and differentiation of stem cells.
    Type: Application
    Filed: October 18, 2007
    Publication date: June 26, 2008
    Applicant: The Johns Hopkins University
    Inventors: Hai-Quan Mao, Leong Kam, Kian-Ngiap Chua, Sreeram Ramakrishna