Patents by Inventor Kieran RYAN

Kieran RYAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250034584
    Abstract: A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression (“an ISY protein”) is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein of Camelina sativa comprising SEQ ID NO: 2 or a fragment, Camelina sativa homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.
    Type: Application
    Filed: August 30, 2024
    Publication date: January 30, 2025
    Inventors: Jihong TANG, Meghna MALIK, Nirmala SHARMA, Claire BURKITT, Yuanyuan JI, Madana M.R. AMBAVARAM, Kieran RYAN, Oliver P. PEOPLES, Kristi D. SNELL, Frank Anthony SKRALY, Venkatesh BOLLINA
  • Patent number: 12084672
    Abstract: A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression (“an ISY protein”) is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein of Camelina sativa comprising SEQ ID NO: 2 or a fragment, Camelina sativa homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: September 10, 2024
    Assignee: Yield10 Bioscience, Inc.
    Inventors: Jihong Tang, Meghna Malik, Nirmala Sharma, Claire Burkitt, Yuanyuan Ji, Madana M. R. Ambavaram, Kieran Ryan, Oliver P. Peoples, Kristi D. Snell, Frank Anthony Skraly, Venkatesh Bollina
  • Publication number: 20210348182
    Abstract: A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression (“an ISY protein”) is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein of Camelina sativa comprising SEQ ID NO: 2 or a fragment, Camelina sativa homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.
    Type: Application
    Filed: September 3, 2019
    Publication date: November 11, 2021
    Inventors: Jihong TANG, Meghna MALIK, Nirmala SHARMA, Claire BURKITT, Yuanyuan JI, Madana M.R. AMBAVARAM, Kieran RYAN, Oliver P. PEOPLES, Kristi D. SNELL, Frank Anthony SKRALY, Venkatesh BOLLINA
  • Publication number: 20200347394
    Abstract: Plant transcription factors and genes encoding the transcription factors are disclosed. Methods to enhance characteristics in a plant by downregulating the genes encoding the transcription factors also are disclosed. The enhanced characteristics can include higher photosynthesis rates, reduced photorespiration rates, higher biomass yield or content, higher seed yield, improved harvest index, higher oil content, improved nutritional composition, improved nitrogen use efficiency, drought resistance, flood resistance, disease resistance, faster seed germination and plant emergence, improved seedling vigor, salt tolerance, higher CO2 assimilation rate, and lower transpiration rate. Modified plants in which the genes encoding the transcription factors are downregulated also are disclosed. Compositions of the invention comprise polynucleotide sequences, polypeptide sequences, variants, orthologs, and fragments thereof.
    Type: Application
    Filed: November 2, 2018
    Publication date: November 5, 2020
    Inventors: Madana M.R. AMBAVARAM, Jihong TANG, Mariya SOMLEVA, Kieran RYAN, Oliver P. PEOPLES, Kristi D. SNELL