Patents by Inventor Kim Andresen

Kim Andresen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PCR controls
    Patent number: 11555222
    Abstract: The present invention provides a method of quantification of a target nucleic acid, using at least any two of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4 as control genes. In particular, the combination of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4, known as the 4Plex, is provided as a control for nucleic acid quantification. The 4Plex has particular utility as a control for nucleic acid quantification by methylation-specific droplet digital PCR.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: January 17, 2023
    Assignee: OSLO UNIVERSITETSSYKEHUS HF
    Inventors: Guro E. Lind, Marine Jeanmougin, Heidi D. Pharo, Kim Andresen, Ragnhild Lothe
  • PCR CONTROLS
    Publication number: 20210032701
    Abstract: The present invention provides a method of quantification of a target nucleic acid, using at least any two of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4 as control genes. In particular, the combination of the genes SYT10, EPHA3, PLEKHF1 and KBTBD4, known as the 4Plex, is provided as a control for nucleic acid quantification. The 4Plex has particular utility as a control for nucleic acid quantification by methylation-specific droplet digital PCR.
    Type: Application
    Filed: November 30, 2018
    Publication date: February 4, 2021
    Inventors: Guro E. LIND, Marine JEANMOUGIN, Heidi D. PHARO, Kim ANDRESEN, Lothe RAGNHILD
  • Method of Threshold Estimation in Digital PCR
    Publication number: 20190221286
    Abstract: A method of estimating thresholds for droplet digital polymerase chain reaction (ddPCR) experiments is described. The method comprises receiving amplitude values for multiple ddPCR experiments and, for each experiment, determining if the distribution of amplitude values is multimodal or unimodal. In the case of unimodality where the amplitude values have a single component then a threshold for the experiment is defined as the maximum amplitude value. In the case of multimodality where the amplitude values hence include multiple components then a threshold for the experiment is defined as the mean between the medians of the first two components. The method thereby obtains individual thresholds for each of the multiple ddPCR experiments.
    Type: Application
    Filed: January 11, 2019
    Publication date: July 18, 2019
    Inventors: Guro E. Lind, Marine Jeanmougin, Heidi D. Pharo, Kim Andresen, Ragnhild Lothe
  • METHODS AND BIOMARKERS FOR DETECTION OF GASTROINTESTINAL CANCERS
    Publication number: 20140031257
    Abstract: The present invention relates to methods and biomarkers (e.g., epigenetic biomarkers) for detection of gastrointestinal cancers (e.g., colorectal cancer, gastric cancer, pancreatic cancer, liver cancer, cancer of the gall bladder and/or bile ducts (e.g., cholangiocarcinoma)) in biological samples (e.g., tissue samples, stool samples, blood samples, plasma samples, cell samples, gall samples, bile samples, serum samples).
    Type: Application
    Filed: March 8, 2012
    Publication date: January 30, 2014
    Applicant: OSLO UNIVERSITETSSYKEHUS HF
    Inventors: Ragnhild A. Lothe, Guro E. Lind, Deeqa Ahmed, Kim Andresen, Rolf I. Skotheim