Patents by Inventor Kim Dix

Kim Dix has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040072203
    Abstract: This invention provides methods for purifying nucleic acids, in particular primer extension products such as those obtained in nucleic acid sequencing reactions. The methods involve the use of a primer to which is attached a string of arylboronic acid moieties. After extension of the primer using a polymerase, the primer extension-products are complexed with a solid support to which is attached an arylboronic acid complexing moiety. The resulting complex is separated from the reaction mixture, washed, and the primer extension products are dissociated from the solid support. The primer extension products are obtained in a form particularly suitable for loading directly on a capillary electrophoresis apparatus.
    Type: Application
    Filed: April 16, 2003
    Publication date: April 15, 2004
    Applicant: Prolinx, Inc.
    Inventors: Connie Kim Dix, Karin A. Hughes, Robert J. Kaiser, Mark L. Stolowitz
  • Publication number: 20010049438
    Abstract: This invention provides methods for purifying nucleic acids, in particular primer extension products such as those obtained in nucleic acid sequencing reactions. The methods involve the use of a primer to which is attached a string of arylboronic acid moieties. After extension of the primer using a polymerase, the primer extension products are complexed with a solid support to which is attached an arylboronic acid complexing moiety. The resulting complex is separated from the reaction mixture, washed, and the primer extension products are dissociated from the solid support. The primer extension products are obtained in a form particularly suitable for loading directly on a capillary electrophoresis apparatus.
    Type: Application
    Filed: July 8, 1999
    Publication date: December 6, 2001
    Inventors: CONNIE KIM DIX, KARIN A. HUGHES, ROBERT J. KAISER, MARK L. STOLOWITZ
  • Patent number: 5378604
    Abstract: This invention relates to compositions of oligonucleotide probes for use in the detection of bacteria associated with medical disorders of the human mouth, wherein said probes consist essentially of a segment of nucleic acid capable of selectively hybridizing under hybridizing conditions, to the 16S or 23S ribosomal RNA [rRNA] of said bacteria. Methods for detection, as well as diagnostic kits for the assay of these bacterium, are also disclosed.
    Type: Grant
    Filed: January 12, 1993
    Date of Patent: January 3, 1995
    Assignee: MicroProbe Corporation
    Inventors: Dennis E. Schwartz, Roy H. Kanemoto, Susan M. Watanabe, Kim Dix
  • Patent number: 5212059
    Abstract: This invention relates to compositions of oligonucleotide probes for use in the detection of bacteria associated with medical disorders of the human mouth, wherein said probes consist essentially of a segment of nucleic acid capable of selectively hybridizing under hybridizing conditions, to the 16S or 23S ribosomal RNA [rRNA] of said bacteria. Methods for detection, as well as diagnostic kits for the assay of these bacterium, are also disclosed.
    Type: Grant
    Filed: August 29, 1990
    Date of Patent: May 18, 1993
    Assignee: MicroProbe Corporation
    Inventors: Dennis E. Schwartz, Roy H. Kanemoto, Susan M. Watanabe, Kim Dix