Patents by Inventor Kim F. Albizati

Kim F. Albizati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REUSABLE INITIATORS FOR SYNTHESIZING NUCLEIC ACIDS
    Publication number: 20230227880
    Abstract: The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using renewable initiators coupled to a solid support. Using the methods of the invention, specific sequences of polynucleotides can be synthesized de novo, base by base, in an aqueous environment, without the use of a nucleic acid template.
    Type: Application
    Filed: July 11, 2022
    Publication date: July 20, 2023
    Inventors: J. William Efcavitch, Kim F. Albizati, Natasha Paul, Sanjay Agarwalla
  • Process of producing phosphinothricin employing nitrilases
    Patent number: 10428092
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: October 1, 2019
    Assignee: Strategic Enzyme Applications, Inc.
    Inventors: Kim F. Albizati, Spiros Kambourakis
  • PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES
    Publication number: 20170247399
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Application
    Filed: May 15, 2017
    Publication date: August 31, 2017
    Applicant: Strategic Enzyme Applications, Inc.
    Inventors: Kim F. Albizati, Spiros Kambourakis, Alan Grubbs, Bennett C. Borer
  • Process of producing phosphinothricin employing nitrilases
    Patent number: 9683001
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Grant
    Filed: March 4, 2015
    Date of Patent: June 20, 2017
    Assignee: Stragegic Enzyme Applications, Inc.
    Inventors: Kim F. Albizati, Spiros Kambourakis, Alan Grubbs, Bennett C. Borer
  • Process of Producing Phosphinothricin Employing Nitrilases
    Publication number: 20150239917
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Application
    Filed: March 4, 2015
    Publication date: August 27, 2015
    Applicant: STRATEGIC ENZYME APPLICATIONS, INC.
    Inventors: Kim F. Albizati, Spiros Kambourakis, Alan Grubbs, Bennett C. Borer
  • Process of producing phosphinothricin employing nitrilases
    Patent number: 8981142
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Grant
    Filed: April 14, 2010
    Date of Patent: March 17, 2015
    Assignee: Strategic Enzyme Applications, Inc.
    Inventors: Kim F. Albizati, Spiros Kambourakis, Alan Grubbs, Bennett C. Borer
  • PROCESS OF PRODUCING PHOSPHINOTHRICIN EMPLOYING NITRILASES
    Publication number: 20130204031
    Abstract: The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
    Type: Application
    Filed: April 14, 2010
    Publication date: August 8, 2013
    Applicant: STRATEGIC ENZYME APPLICATIONS, INC.
    Inventors: Kim F. Albizati, Spiros Kambourakis, Alan Grubbs, Bennett C. Borer
  • Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
    Patent number: 6465661
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: March 21, 2002
    Date of Patent: October 15, 2002
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
    Patent number: 6392067
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: May 21, 2002
    Assignees: Agouron Pharmaceuticals, Inc., Japan Tobacco Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
    Patent number: 6316625
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: November 13, 2001
    Assignees: Agouron Pharmaceuticals, Inc., Japan Tobacco Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
    Patent number: 6117999
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: February 19, 1999
    Date of Patent: September 12, 2000
    Assignees: Agouron Phramaceuticals, Inc., Japan Tobacco, Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • Intermediates for making HIV-protease inhibitors
    Patent number: 6084107
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: July 4, 2000
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • HIV protease inhibitors
    Patent number: 6001851
    Abstract: HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: December 14, 1999
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Kim F. Albizati, Siegfried H. Reichi, Michael D. Varney, Kanyin E. Zhang, Takuo Kobayashi
  • Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
    Patent number: 5925759
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: July 20, 1999
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati
  • Intermediates for making HIV-protease inhibitors
    Patent number: 5705647
    Abstract: HIV protease inhibitors inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds can be prepared by the novel methods of the present invention using the novel inventive intermediates.
    Type: Grant
    Filed: September 5, 1996
    Date of Patent: January 6, 1998
    Assignees: Agouron Pharmaceuticals, Inc., Japan Tobacco, Inc.
    Inventors: Srinivasan Babu, Bennett C. Borer, Travis P. Remarchuk, Robert J. Szendroi, Kathleen R. Whitten, Juliette K. Busse, Kim F. Albizati