Abstract: Fas-associated factor 1 (FAF1) protein-loaded exosomes and a cancer treatment using FAF1 protein-loaded exosomes are disclosed. FAF1 protein-loaded exosomes are isolated from HEK 293 cells in which FAF1 having a known tumor-suppressive function is overexpressed and administered the FAF1 protein-loaded exosomes to various tumor models in which pancreatic cancer cells (MIA PaCa-2), lung cancer cells (A549), colon cancer cells (HCT 116), liver cancer cells (Hep3B), breast cancer cells (MDA-MB-231), kidney cancer cells (Caki-1) and cervical cancer cell (HeLa cell) are transplanted into nude mice through intratumoral injection. The administration exhibited tumor growth inhibitory effects remarkably greater than those of a control group not treated with FAF1.

Abstract: A semiconductor device including a semiconductor substrate including a chip region and an edge region around the chip region; a lower dielectric layer and an upper dielectric layer on the semiconductor substrate; a redistribution chip pad that penetrates the upper dielectric layer on the chip region and is connected a chip pad; a process monitoring structure on the edge region; and dummy elements in the edge region and having an upper surface lower than an upper surface of the upper dielectric layer.

Abstract: The present invention relates to an anti-inflammatory composition comprising Epimedium koreanum Nakai, Polygala tenuifolia Willd, and Polyporus umbellatus Fries extracts or a mixture thereof as an active ingredient. The extracts and mixture prepared according to the present invention exhibit a high inhibitory effect against nitric oxide and a suppressive effect against the expression of iNOS and COX2 and thus can be advantageously used as an anti-inflammatory composition.

Abstract: An embodiment multi-way coolant valve includes an outer housing including first to third outer inlets, first to third outer outlets, and a pump mount portion coupled to one of the outer outlets, an inner housing rotatably provided within the outer housing and including penetration holes corresponding to the outer inlets and outlets, a coolant line defined by a selective connection of the penetration holes such that the outer inlets and outlets are selectively connected, pads interposed between an interior circumference of the outer housing and an exterior circumference of the inner housing at locations of the outer inlets and outlets, respectively, and a driving device connected to a rotation center of the inner housing to selectively rotate the inner housing within the outer housing, wherein the inner housing is configured to rotate by a preset interval according to a selected vehicle mode.

Abstract: Disclosed herein are a multi-target analysis apparatus and method. The multi-target analysis apparatus includes: an input/output interface configured to receive data and output the results of computation of the data; storage configured to store a program for performing a multi-target analysis method; and a controller provided with at least one process, and configured to analyze multiple targets received through the input/output interface by executing the program. The controller is further configured to: collect instruction-target pairs in each of which an instruction and state information for a target are matched with each other so that the target is specified through the instruction, and generate an instruction-target set having a plurality of instruction-target pairs; and train a reinforcement learning-based learning model configured to receive the instruction for the target and the state information for the target and output action information by referring to the instruction-target set.

Abstract: Disclosed are a sub-mount, an optical modulation module, and an optical communication device. The sub-mount includes a mount substrate, a signal electrode extending in a first direction on the mount substrate, and a ground electrode separated from the signal electrode and disposed on the mount substrate. Here, the ground electrode includes a lower electrode disposed on a bottom surface of the mount substrate and upper electrodes disposed on one side of the mount substrate and connected to the lower electrode through a side surface or the inside of the mount substrate.

Abstract: An organic electroluminescence device of an embodiment includes a first electrode, a second electrode, and an emission layer between the first electrode and the second electrode, and the emission layer includes a compound represented by Formula 1 below, and thus the organic electroluminescence device may exhibit high luminous efficiency characteristics and improved service life characteristics.

Abstract: An embodiment roof reinforcement structure for a vehicle includes side body structures disposed on both sides of a vehicle body along a front to rear direction of the vehicle body, each of the side body structures including front and rear quarter completements at a front and a rear of the vehicle body, respectively, and a roof side inner member and a roof side panel connecting the front and rear quarter completements, a roof side inner bracket connected to the roof side inner member, a roof side outer assembly connected to the roof side inner bracket, and a roof side outer reinforcement member connected to the roof side inner bracket, the roof side outer assembly, and at least one of the front or the rear quarter completement on one of the sides of the vehicle body.

Abstract: An integrated circuit device includes a substrate and a first electrically insulating layer on the substrate. An electrically conductive contact plug is provided, which extends at least partially through the first electrically insulating layer. The contact plug includes a protrusion having a top surface that is spaced farther from the substrate relative to a top surface of a portion of the first electrically insulating layer extending adjacent the contact plug. An electrically conductive line is provided with a terminal end, which extends on a first portion of the protrusion. A second electrically insulating layer is provided, which extends on a second portion of the protrusion and on the first electrically insulating layer. The second electrically insulating layer has a sidewall, which extends opposite a sidewall of the terminal end of the electrically conductive line.

Abstract: Provided is an image processing system and a disparity calculation method. An image processing device included in the image processing system includes a preprocessor configured to determine an effective range of a focal length of an image sensor based on first disparities measured at a plurality of focal lengths of an object having a fixed position from the image sensor, and determine a representative value of equivalent aperture values for the image sensor corresponding to the effective range based on the first disparities. The image processing device also includes a disparity calculator configured to calculate a second disparity of the target object within the effective range based on the focal length, a first distance, a second distance, and the representative value of the equivalent aperture values.

Abstract: There is provided a method and an apparatus for efficiently recovering an amide-based compound such as N-methyl-2-pyrrolidone from an aqueous solution containing an amide-based compound such as N-methyl-2-pyrrolidone.

Abstract: The present disclosure relates to a non-alcoholic fatty liver artificial tissue model. As compared to a conventional technology by which tissues are cultured only in Matrigel including a device composed of a decellularized liver tissue-derived extracellular matrix and a plurality of microchannels or a decellularized liver tissue-derived extracellular matrix, the present disclosure enables better mimicking of an actual non-alcoholic fatty liver disease due to the presence of Kupffer cells and hepatic stellate cells. Also, according to the present disclosure, the growth of liver organoids can be improved and fat accumulation and inflammation in the liver organoids can be caused to occur well through free fatty acid treatment, and the phenotypes of non-alcoholic fatty liver can be better expressed.

Abstract: The contrastive learning method based on implications for detecting implicit hate expression, an apparatus, and a computer program for performing the same according to the exemplary embodiment of the present disclosure perform the contrastive learning based on implications of implicit hate expression to detect the implicit hate expression to train a network model having a higher generalization performance for the implicit hate expression.

Abstract: Disclosed are a method of manufacturing an electrode for a rechargeable lithium battery, and an electrode manufactured therefrom, and a rechargeable lithium battery including the electrode, the method of manufacturing an electrode for a rechargeable lithium battery including mixing together an electrode active material and a first ionic polymer to prepare a first slurry; mixing together the first slurry and a second ionic polymer to prepare a second slurry; mixing together the second slurry and a water-soluble binder to prepare an electrode active material layer slurry; coating the electrode active material layer slurry on a current collector, drying and compressing the electrode active material layer slurry to manufacture an electrode for a rechargeable lithium battery, wherein an amount of the first ionic polymer is about 20 to about 90 wt % based on a total amount of 100 wt % of the first ionic polymer and the second ionic polymer.

Abstract: A method of manufacturing an electrode for a rechargeable lithium battery, an electrode manufactured therefrom, and a rechargeable lithium battery including the electrode are provided. The method includes preparing an electrode active material layer slurry including an electrode active material and a polymer binder, coating the electrode active material layer slurry on a current collector and drying it while applying an electric field to form an active material layer, wherein the polymer binder includes a water-soluble binder and an ionic polymer.

Abstract: In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens of higher quality, in which the reaction temperature of a diamine hydrochloride composition and triphosgene is controlled to a specific range, or a crude diisocyanate composition obtained from the reaction of a diamine hydrochloride composition and triphosgene is distilled at a specific temperature range, or the molar ratio of a diamine hydrochloride and triphosgene is adjusted to a specific range.

Abstract: An embodiment swing door mounting structure for a vehicle includes a roof side reinforcement member coupled to an inner side of a cross section of a roof side of a side structure in a vehicle body front and rear direction and a door mounting member coupled to the roof side reinforcement member to define an open cross section for mounting a swing door on the roof side.

Abstract: An embodiment roof structure of a vehicle is provided. The roof structure is coupled to side structures disposed along a vehicle width direction and is configured to mount a roof module. The roof structure includes a side upper reinforce assembly coupled to an upper interior of the side structures along a vehicle length direction and a plurality of roof rail assemblies arranged along the vehicle length direction, each of the plurality of roof rail assemblies being coupled to the side upper reinforce assembly by extending along the vehicle width direction into a cross-sectional interior of an upper portion of each of the side structures.

Abstract: The present disclosure relates to a preparation method for a super absorbent polymer capable of minimizing bubble loss during foam polymerization by a radical polymerization method. According to the preparation method of the present disclosure, a super absorbent polymer having a high surface area can be manufactured by forming many small and uniform pores. Since it exhibits an excellent absorption rate, it can be used in various products requiring high absorption properties.

Abstract: A surface plasmon resonance imaging apparatus is provided. The surface plasmon resonance imaging apparatus includes a light irradiation unit configured to irradiate polarized light onto a metal coating film provided on one surface of a prism, a light modulator configured to spatially pattern-encode light reflected by the metal coating film and the prism, a light detector configured to detect a pattern-encoded light signal, obtained through pattern-encoding by the light modulator, as a spectral signal, a signal processor configured to spatially decode the spectral signal and analyze a decoded spectral signal to generate characteristic data of a sample provided on the metal coating film, and an output unit configured to output the characteristic data of the sample as a two-dimensional (2D) image.