Abstract: The present invention provides, among other things, methods of treating ornithine transcarbamylase deficiency, including administering to a subject in need of treatment a composition comprising an mRNA encoding an ornithine transcarbamylase protein at a low dose and at an administration interval such that at least one symptom or feature of the OTC deficiency is reduced.

Abstract: Provided are a method and system of analyzing ingredients of an artificial rainfall for verification of a cloud seeding effect. As the method and system, which can verify an effect of the artificial rainfall in such a manner that a seeding material becomes different according to each temperature of clouds at a seeding altitude, water sampling from precipitation is performed before and after seeding, and thus the ingredients of a water sample are analyzed using each of a method of analyzing a heavy metal component and a method of analyzing a water-soluble ion component according to a cool cloud and a warm cloud so that whether or not there is a change in each concentration of the ingredients can be determined, are provided, an experiment for the artificial rainfall can more effectively be performed.

Abstract: A camshaft drive system for an internal combustion engine includes a drive sprocket fixed upon a crankshaft of the engine and a driven sprocket fixed upon a camshaft of the engine. A flexible power transmission element extends between the drive sprocket and driven sprocket. A tensioning device for the flexible power transmission element includes a linear actuator and a number of movable contactors for engaging and tensioning both the slack side and the tight side of the power transmission element, such that proper phasing of the camshaft with respect to the crankshaft is maintained.

Abstract: A camshaft drive system for an internal combustion engine includes a drive sprocket fixed upon a crankshaft of the engine and a driven sprocket fixed upon a camshaft of the engine. A flexible power transmission element extends between the drive sprocket and driven sprocket. A tensioning device for the flexible power transmission element includes a linear actuator and a number of movable contactors for engaging and tensioning both the slack side and the tight side of the power transmission element, such that proper phasing of the camshaft with respect to the crankshaft is maintained.

Abstract: An intake and exhaust system for a dual mode HCCI engine, which provides superior intake temperature control and homogeneity for engine operation in SI and HCCI modes, as well as during transition between SI and HCCI modes and vice-versa. The system includes adjusted intake cam movement event lengths for intake valve operation at specified modes of operation. The system further includes at least one cam profile switching device operatively connected to intake and exhaust valves in an engine for controlling event length, maximum lift, and valve opening/closing timings for the intake and exhaust valves. The system yet further includes a bifurcated intake system and camless valve actuators for controlling intake valves for facilitating operation in SI or HCCI modes, as well as transition between SI and HCCI modes and vice-versa.

Abstract: An intake and exhaust system for a dual mode HCCI engine, which provides superior intake temperature control and homogeneity for engine operation in SI and HCCI modes, as well as during transition between SI and HCCI modes and vice-versa. The system includes adjusted intake cam movement event lengths for intake valve operation at specified modes of operation. The system further includes at least one cam profile switching device operatively connected to intake and exhaust valves in an engine for controlling event length, maximum lift, and valve opening/closing timings for the intake and exhaust valves. The system yet further includes a bifurcated intake system and camless valve actuators for controlling intake valves for facilitating operation in SI or HCCI modes, as well as transition between SI and HCCI modes and vice-versa.

Abstract: An internal combustion engine cylinder head camshaft bearing ladder 210, is provided which includes a first body with an aperture to facilitate threaded connection 202 of the body to a cylinder head 2 with a cut out 212 for receiving a cam shaft 67, the first body also having a pocket 218, and a solenoid actuator 220 positioned within the pocket 218 for activating a switchable rocker arm assembly 9.

Abstract: An intake and exhaust system for a dual mode HCCI engine, which provides superior intake temperature control and homogeneity for engine operation in SI and HCCI modes, as well as during transition between SI and HCCI modes and vice-versa. The system includes adjusted intake cam movement event lengths for intake valve operation at specified modes of operation. The system further includes at least one cam profile switching device operatively connected to intake and exhaust valves in an engine for controlling event length, maximum lift, and valve opening/closing timings for the intake and exhaust valves. The system yet further includes a bifurcated intake system and camless valve actuators for controlling intake valves for facilitating operation in SI or HCCI modes, as well as transition between SI and HCCI modes and vice-versa.

Abstract: A poppet valve operating system for an internal combustion engine includes a finger follower which is driven by an intermediate rocker. The intermediate rocker selectively converts motion imparted by a drive cam into either a purely translational trajectory, or into a mixed translational and rotational trajectory, so as to open a poppet valve which is ultimately actuated by a finger follower interposed between the intermediate rocker and the valve.

Abstract: A cam cover gasket 207 is provided which includes a generally compliant first material 210 having an upper surface for contact with a cover 200 and a lower surface for contact with an engine head 2, a generally rigid bracket frame of a second material 222 connected with the first material 210, and a solenoid actuator 232 connected with the second material 222.

Abstract: A cam cover gasket 207 is provided which includes a generally compliant first material 210 having an upper surface for contact with a cover 200 and a lower surface for contact with an engine head 2, a generally rigid bracket frame of a second material 222 connected with the first material 210, and a solenoid actuator 232 connected with the second material 222.

Abstract: An internal combustion engine cylinder head camshaft bearing ladder 210, is provided which includes a first body with an aperture to facilitate threaded connection 202 of the body to a cylinder head 2 with a cut out 212 for receiving a cam shaft 67, the first body also having a pocket 218, and a solenoid actuator 220 positioned within the pocket 218 for activating a switchable rocker arm assembly 9