Patents by Inventor Kim Paulsen

Kim Paulsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for purifying nucleic acids from stabilization reagents
    Patent number: 10947527
    Abstract: The invention features reagents, methods and kits for the purification of RNA, or DNA, or both, from a sample.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: March 16, 2021
    Assignee: QIAGEN North American Holdings, Inc
    Inventors: Robert Jackson Bair, Kim Paulsen
  • COMPOSITIONS AND METHODS FOR PURIFYING NUCLEIC ACIDS FROM STABILIZATION REAGENTS
    Publication number: 20190345480
    Abstract: The invention features reagents, methods and kits for the purification of RNA, or DNA, or both, from a sample.
    Type: Application
    Filed: November 27, 2018
    Publication date: November 14, 2019
    Inventors: Robert Jackson Bair, Kim Paulsen
  • Triazole compounds and their use as gamma secretase modulators
    Patent number: 9718805
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: August 1, 2017
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Jonas Malmborg
  • Triazole compounds and their use as gamma secretase modulators
    Patent number: 9611254
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: April 4, 2017
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Gunnar Nordvall, Istvan Macsari, Jonas Malmborg
  • Pyrimidine compounds and their use as gamma secretase modulators
    Patent number: 9439904
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: September 13, 2016
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Istvan Macsari, Jonas Malmborg, Alexander Paptchikhine, Per Arvidsson
  • PYRIMIDINE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160129002
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 12, 2016
    Applicant: Acturum Life Science AB
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian Erik LINDE, Istvan MACSARI, Jonas MALMBORG, Alexander PAPTCHIKHINE, Per ARVIDSSON
  • TRIAZOLE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160122326
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 5, 2016
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian LINDE, Gunnar NORDVALL, Istvan MACSARI, Jonas MALMBORG
  • TRIAZOLE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160108022
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: April 21, 2016
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian Erik LINDE, Jonas MALMBORG
  • Compositions and methods for using a solid support to purify DNA
    Patent number: 8598338
    Abstract: The present disclosure provides methods for isolating substantially pure and undegraded DNA from biological material via a solid support. The methods may use a DNA lysing solution that comprises a surfactant, a DNA-complexing salt (e.g., a lithium salt), and a buffer. Alternatively, the methods may use a solid support pre-treated with the DNA lysing solution.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: December 3, 2013
    Assignee: QIAGEN North American Holdings, Inc.
    Inventors: Robert Jackson Bair, Kristen Campbell Benedict, Wendy J. Kivens, Robert W. Kwiatkowski, Jr., Kim Paulsen, Daniel A. Strom, John M. Wages
  • Dihydropyridopyrimidines for the treatment of AB-related pathologies
    Patent number: 8188101
    Abstract: Dihydropyridopyrimidine compounds of formula (Ia) and therapeutically acceptable salts thereof, wherein R1, R2 and Z are as defined in the specification; processes for making them and methods for using them in the treatment of A?-related pathologies.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: May 29, 2012
    Assignee: AstraZeneca AB
    Inventors: Rickard Forsblom, Kim Paulsen, Didier Rotticci, Ellen Santangelo, Magnus Waldman
  • Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases
    Publication number: 20120122843
    Abstract: The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compounds, processes for making said compounds, and their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: ASTRAZENECA AB
    Inventors: István MACSÁRI, Kim PAULSEN, Laszlo RAKOS, Britt-Marie SWAHN, Magnus WALDMAN, Didier ROTTICCI, Stefan VON BERG
  • COMPACT APPARATUS, COMPOSITIONS AND METHODS FOR PURIFYING NUCLEIC ACIDS
    Publication number: 20120058011
    Abstract: The invention features an apparatus, materials and methods for isolating RNA or DNA from a sample.
    Type: Application
    Filed: September 1, 2011
    Publication date: March 8, 2012
    Inventors: Alan Wirbisky, Tim Quinn, Nick Van Der Lught, Nate Morken, Rebecca Johnson, Kim Paulsen, Dan Strom, Jim Baldrica
  • Novel Compounds for A-Beta-Related Pathologies
    Publication number: 20100292210
    Abstract: The present invention relates to novel compounds of formulae I and II and therapeutically acceptable salts thereof, their pharmaceutical compositions processes for making them and their use in therapeutic methods for treatment and/or prevention of various diseases. In particular, the invention relates to compounds which interfere with ?-secretase and/or its substrate and hence modulate the formation of A? peptides.
    Type: Application
    Filed: May 11, 2010
    Publication date: November 18, 2010
    Applicant: AstraZeneca AB
    Inventors: Yvonne Lo-Alfredsson, Kim Paulsen, Laszlo Rakos, Didier Rotticci, Magnus Waldman
  • COMPOSITIONS AND METHODS FOR USING A SOLID SUPPORT TO PURIFY DNA
    Publication number: 20100160619
    Abstract: Reagents, methods and kits for the purification of DNA from biological materials are provided.
    Type: Application
    Filed: March 5, 2010
    Publication date: June 24, 2010
    Applicant: Qiagen North American Holdings, Inc.
    Inventors: Robert Jackson Bair, Kristen Campbell Benedict, Wendy J. Kivens, Robert W. Kwiatkowski, JR., Kim Paulsen, Daniel A. Strom, John M. Wages
  • COMPOUNDS 563
    Publication number: 20100130495
    Abstract: The present invention relates to novel compounds of formula I and therapeutically acceptable salts thereof, their pharmaceutical compositions, processes for making them and their use as therapeutic methods for treatment and/or prevention of various diseases.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 27, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Rickard FORSBLOM, Kim PAULSEN, Didier ROTTICCI, Ellen SANTANGELO, Magnus WALDMAN
  • Compact apparatus, compositions and methods for purifying nucleic acids
    Publication number: 20070092403
    Abstract: The invention features an apparatus, materials and methods for isolating RNA or DNA from a sample.
    Type: Application
    Filed: October 21, 2005
    Publication date: April 26, 2007
    Inventors: Alan Wirbisky, Tim Quinn, Nick Lught, Nate Morken, Rebecca Johnson, Kim Paulsen, Dan Strom, Jim Baldrica
  • Compositions and methods for using a solid support to purify RNA
    Publication number: 20070043216
    Abstract: Reagents, methods and kits for the purification of RNA from biological materials are provided.
    Type: Application
    Filed: October 30, 2006
    Publication date: February 22, 2007
    Applicant: Gentra Systems, Inc.
    Inventors: Robert Bair, Ellen Heath, Heather Meehan, Kim Paulsen, John Wages
  • Compositions and methods for purifying nucleic acids from stabilization reagents
    Publication number: 20060105372
    Abstract: The invention features reagents, methods and kits for the purification of RNA, or DNA, or both, from a sample.
    Type: Application
    Filed: November 3, 2005
    Publication date: May 18, 2006
    Inventors: Robert Bair, Kim Paulsen
  • Formulations and methods for denaturing proteins
    Publication number: 20050171333
    Abstract: Reagents, methods and kits for denaturation of protein are provided.
    Type: Application
    Filed: December 15, 2004
    Publication date: August 4, 2005
    Inventor: Kim Paulsen
  • Compositions and methods for using a solid support to purify DNA
    Publication number: 20050032105
    Abstract: Reagents, methods and kits for the purification of DNA from biological materials are provided.
    Type: Application
    Filed: August 2, 2004
    Publication date: February 10, 2005
    Inventors: Robert Bair, Kristen Benedict, Wendy Kivens, Robert Kwiatkowski, Kim Paulsen, Daniel Strom, John Wages