Patents by Inventor Kim Samirah ROBINSON

Kim Samirah ROBINSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL METHOD TO BLOCK INFLAMMATORY CELL DEATH AND IL-1BETA SECRETION CAUSED BY RIBOTOXINS AND UV IRRADIATION USING GENETIC AND CHEMICAL INHIBITORS OF ZAKA AND THE NLRP1 INFLAMMASOME
    Publication number: 20240148728
    Abstract: The present invention is directed to a method of modulating inflammation and/or related complications triggered by ZAK? kinase-activated NLRP1-driven pyroptosis; a compound or composition comprising said compound for use in the method, and use of said compounds in medicament preparation. More particularly, the inflammation is caused by a ribotoxin or UVB irradiation. Inhibition of said ZAK? kinase-activated NLRP1-driven pyroptosis may be used in the prophylaxis or treatment of human airway or skin inflammation and/or related complications, whereas activation of ZAK? kinase-activated NLRP1-driven pyroptosis may be used in the prophylaxis or treatment of cancer.
    Type: Application
    Filed: February 23, 2022
    Publication date: May 9, 2024
    Inventors: Lei ZHONG, Kim Samirah ROBINSON, Gee Ann TOH, Zijin SUN
  • USE OF A COMPOUND OR COMPOSITION COMPRISING AN INHIBITOR OF NLRP1 INFLAMMASOME ACTIVATION FOR THE TREATMENT OF HUMAN AIRWAY INFLAMMATION
    Publication number: 20230172933
    Abstract: The present invention provides a method of prophylaxis or treatment of airway inflammation and/or related complications triggered by Enterovirus 3C protease-activated NLRP1, a compound or composition comprising said compound for use in the method, and use of said compounds in medicament preparation for the prophylaxis or treatment of human airway inflammation and/or related complications triggered by Enterovirus 3C protease-activated NLRP1.
    Type: Application
    Filed: March 18, 2021
    Publication date: June 8, 2023
    Inventors: Lei ZHONG, Bruno REVERSADE, Kim Samirah ROBINSON