Patents by Inventor Kim Trang Huu NGUYEN

Kim Trang Huu NGUYEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclodextrins with one or more poly(ethylene glycol) units, inclusion compounds and drug delivery vehicles including the same, and methods of making and using the same
    Patent number: 10208167
    Abstract: A compound comprising a cyclodextrin and a monoalkoxy polyethylene glycol linked thereto through an ether bond (a “pegylated cyclodextrin”) is disclosed, as are drug delivery vehicles and pharmaceutical formulations including the same, and methods for making the compound and the drug delivery vehicle and for delivering the drug to a patient in need thereof. The method of making includes the steps of creating either a tosylated monoalkoxy polyethylene glycol or a tosylated cyclodextrin, and either reacting the tosylated monoalkoxy polyethylene glycol with a deprotonated cyclodextrin, or reacting the tosylated cyclodextrin with a deprotonated monoalkoxy polyethylene glycol. The present pegylated cyclodextrin readily forms an inclusion compound with certain drugs to protect the drug against adverse interactions with mucin (e.g., in a mucus membrane).
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: February 19, 2019
    Assignee: The Board of Trustees of the California State University
    Inventors: Yong Ba, Kim Trang Huu Nguyen
  • CYCLODEXTRINS WITH ONE OR MORE POLY(ETHYLENE GLYCOL) UNITS, INCLUSION COMPOUNDS AND DRUG DELIVERY VEHICLES INCLUDING THE SAME, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170106100
    Abstract: A compound comprising a cyclodextrin and a monoalkoxy polyethylene glycol linked thereto through an ether bond (a “pegylated cyclodextrin”) is disclosed, as are drug delivery vehicles and pharmaceutical formulations including the same, and methods for making the compound and the drug delivery vehicle and for delivering the drug to a patient in need thereof. The method of making includes the steps of creating either a tosylated monoalkoxy polyethylene glycol or a tosylated cyclodextrin, and either reacting the tosylated monoalkoxy polyethylene glycol with a deprotonated cyclodextrin, or reacting the tosylated cyclodextrin with a deprotonated monoalkoxy polyethylene glycol. The present pegylated cyclodextrin readily forms an inclusion compound with certain drugs to protect the drug against adverse interactions with mucin (e.g., in a mucus membrane).
    Type: Application
    Filed: October 5, 2016
    Publication date: April 20, 2017
    Inventors: Yong BA, Kim Trang Huu NGUYEN