Patents by Inventor Kim Vandegriff

Kim Vandegriff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MalPEG-Hb conjugate-containing compositions for delivering carbon monoxide (CO) to cells
    Patent number: 9138463
    Abstract: The present invention relates to compositions for delivering carbon monoxide (CO) to cells using heme proteins as carriers. In one embodiment, the present invention relates to the use of MalPEG surface modified hemoglobin to deliver CO to cells.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: September 22, 2015
    Inventors: Robert M. Winslow, Nancy Jo Winslow, Kim Vandegriff, Ashok Malavalli
  • MalPEG-Hb Conjugate-Containing Compositions for Delivering Carbon Monoxide (CO) to Cells
    Publication number: 20120094912
    Abstract: The present invention relates to compositions for delivering carbon monoxide (CO) to cells using heme proteins as carriers. In one embodiment, the present invention relates to the use of MalPEG surface modified hemoglobin to deliver CO to cells.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 19, 2012
    Applicant: Sangart, Inc.
    Inventors: Robert M. WINSLOW, Kim Vandegriff, Nancy Jo Winslow, Ashok Malavalli
  • Methods and compositions for oxygen transport comprising a method for making a high oxygen affinity modified hemoglobin
    Publication number: 20070167352
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Application
    Filed: March 13, 2007
    Publication date: July 19, 2007
    Applicant: Sangart, Inc.
    Inventors: Robert Winslow, Kim Vandegriff
  • Methods to enhance hemodynamic stability using oxygen carrying compositions
    Publication number: 20060172924
    Abstract: The present invention relates to methods for enhancing the hemodynamic stability of an individual undergoing surgery by administering a composition comprising a hemoglobin-based oxygen carrier. In one embodiment, the present invention relates to the use of polyalkylene oxide modified hemoglobins with reduced cooperativity and a high oxygen affinity to enhance oxygen offloading as a preventative measure to avoid hemodynamic stability-related complications during surgery.
    Type: Application
    Filed: August 31, 2005
    Publication date: August 3, 2006
    Inventors: Robert Winslow, Kim Vandegriff
  • Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
    Publication number: 20050164915
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Application
    Filed: March 23, 2005
    Publication date: July 28, 2005
    Applicant: Sangart, Inc.
    Inventors: Robert Winslow, Kim Vandegriff
  • Methods and compositions for oxygen transport comprising an oxygen carrier and a crystalloid in hypertonic solution
    Publication number: 20050119161
    Abstract: The present invention relates to blood product compositions, and more particularly to compositions comprising a modified hemoglobin and a crystalloid in an aqueous diluent. The present invention also relates to such blood product compositions which are formulated as hypertonic solutions to provide for low volume rapid restoration of hemodynamic parameters in hypovolemic states.
    Type: Application
    Filed: January 10, 2003
    Publication date: June 2, 2005
    Inventors: Robert Winslow, Kim Vandegriff
  • Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
    Publication number: 20050026816
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Application
    Filed: August 24, 2004
    Publication date: February 3, 2005
    Inventors: Robert Winslow, Kim Vandegriff
  • Methods and compositions for oxygen transport comprising modified hemoglobin in plasma
    Publication number: 20050020485
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified hemoglobin in plasma.
    Type: Application
    Filed: January 10, 2003
    Publication date: January 27, 2005
    Inventors: Robert Winslow, Kim Vandegriff