Patents by Inventor Kim Yang Lee

Kim Yang Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11396675
    Abstract: Apparatus and methods to identify nucleotides of a DNA strand. The method includes exposing the DNA strand to a first dye or peptide, attaching the first dye or peptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptide changing a conductance of the first type of nucleotide to which the first dye or peptide is attached, and measuring a tunneling current signal for all nucleotides of the DNA strand, the changed conductance of the first type of nucleotide providing amplified tunneling current discrimination of the nucleotides of the DNA strand.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: July 26, 2022
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Philip L. Steiner, Kim Yang Lee, David S. Kuo
  • Patent number: 11320397
    Abstract: A DNA sequencing device, and related method, which include an electrode and a plurality of spaced apart alignment structures. The electrode defines an electrode gap, the electrode being operable to detect a change in tunneling current as a DNA strand passes through the electrode gap. The plurality of spaced apart alignment structures are arranged to position nucleotides of the DNA strand in a predetermined orientation as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: May 3, 2022
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, David S. Kuo, Kim Yang Lee, Koichi Wago
  • Patent number: 11136624
    Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: April 29, 2020
    Date of Patent: October 5, 2021
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Kim Yang Lee, David S. Kuo, Thomas Young Chang, Xiaomin Yang, ShuaiGang Xiao, Koichi Wago
  • Publication number: 20210245109
    Abstract: A first wafer has a first stop layer deposited on a substrate, the substrate used to form a base support structure. A second wafer has a second stop layer deposited on a sacrificial substrate, and a filter layer deposited on the second stop layer. A rib layer is deposited on one of: the first stop layer of the first layer; or a third stop layer that is deposited over the filter layer. A rib pattern is formed in the rib layer. The first and second wafers are flip bonded such that the rib pattern is joined between the filter layer and the first stop layer. Elongated voids are formed within the filter layer. The base support structure is formed within the substrate of the first wafer such that there is a fluid flow path between the base support structure, the rib layer, and the elongated voids of the filter layer.
    Type: Application
    Filed: July 9, 2020
    Publication date: August 12, 2021
    Inventors: Thomas Young Chang, Kim Yang Lee, Tan G. Liu, Yautzong Hsu, Shuaigang Xiao
  • Publication number: 20200385799
    Abstract: Apparatus and methods to identify nucleotides of a DNA strand. The method includes exposing the DNA strand to a first dye or peptide, attaching the first dye or peptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptide changing a conductance of the first type of nucleotide to which the first dye or peptide is attached, and measuring a tunneling current signal for all nucleotides of the DNA strand, the changed conductance of the first type of nucleotide providing amplified tunneling current discrimination of the nucleotides of the DNA strand.
    Type: Application
    Filed: August 24, 2020
    Publication date: December 10, 2020
    Inventors: Thomas Young CHANG, Philip L. STEINER, Kim Yang LEE, David S. KUO
  • Publication number: 20200377939
    Abstract: A DNA sequencing device and related methods, wherein the device includes a substrate, a nanochannel formed in the substrate, a first electrode positioned on a first side of the nanochannel, and a second electrode. The second electrode is positioned on a second side of the nanochannel opposite the first electrode and is spaced apart from the first electrode to form an electrode gap that is exposed in the nanochannel. At least a portion of first electrode is movable relative to the second electrode to decrease a size of the electrode gap.
    Type: Application
    Filed: June 23, 2020
    Publication date: December 3, 2020
    Inventors: Kim Yang Lee, Thomas Young Chang, David S. Kuo, ShuaiGang Xiao, Xiaomin Yang, Koichi Wago
  • Publication number: 20200371064
    Abstract: A DNA sequencing device, and related method, which include an electrode and a plurality of spaced apart alignment structures. The electrode defines an electrode gap, the electrode being operable to detect a change in tunneling current as a DNA strand passes through the electrode gap. The plurality of spaced apart alignment structures are arranged to position nucleotides of the DNA strand in a predetermined orientation as the DNA strand passes through the electrode gap.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 26, 2020
    Inventors: Thomas Young CHANG, David S. KUO, Kim Yang LEE, Koichi WAGO
  • Patent number: 10844431
    Abstract: Apparatus and methods to a DNA sequencing device and related methods that includes a substrate, a nanochannel formed in the substrate, a first electrode, a second electrode arranged opposite the first electrode, a distance between the first and second electrodes defining an electrode gap that is exposed within the nanochannel, and at least one actuator operable to move at least one of the first and second electrodes to adjust a size of the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: November 24, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Kim Yang Lee, David S. Kuo, Erik J. Hutchinson
  • Patent number: 10761058
    Abstract: A DNA sequencing device, and related method, which include an electrode and a plurality of spaced apart alignment structures. The electrode defines an electrode gap, the electrode being operable to detect a change in tunneling current as a DNA strand passes through the electrode gap. The plurality of spaced apart alignment structures are arranged to position nucleotides of the DNA strand in a predetermined orientation as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: September 1, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, David S. Kuo, Kim Yang Lee, Koichi Wago
  • Patent number: 10752947
    Abstract: Apparatus and methods to identify nucleotides of a DNA strand. The method includes exposing the DNA strand to a first dye or peptide, attaching the first dye or peptide to a first type of nucleotide (A,T,C,G) of the DNA strand, the first dye or peptide changing a conductance of the first type of nucleotide to which the first dye or peptide is attached, and measuring a tunneling current signal for all nucleotides of the DNA strand, the changed conductance of the first type of nucleotide providing amplified tunneling current discrimination of the nucleotides of the DNA strand.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 25, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Thomas Young Chang, Philip L. Steiner, Kim Yang Lee, David S. Kuo
  • Publication number: 20200255895
    Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.
    Type: Application
    Filed: April 29, 2020
    Publication date: August 13, 2020
    Inventors: Kim Yang LEE, David S. KUO, Thomas Young CHANG, Xiaomin YANG, ShuaiGang XIAO, Koichi WAGO
  • Publication number: 20200249195
    Abstract: A DNA sequencing device, and related methods, include a nanopore or nanochannel structure, and a nanoelectrode. The nanoelectrode includes electrode members having free ends exposed within the nanopore or nanochannel structure, an electrode gap defined between of the free ends, and plated portions formed on the free ends to provide a reduced sized for the electrode gap.
    Type: Application
    Filed: April 21, 2020
    Publication date: August 6, 2020
    Inventors: David S. KUO, Xiaomin YANG, ShuaiGang XIAO, Kim Yang LEE, Koichi R. WAGO, Thomas Young CHANG
  • Patent number: 10731210
    Abstract: A DNA sequencing device and related methods, wherein the device includes a substrate, a nanochannel formed in the substrate, a first electrode positioned on a first side of the nanochannel, and a second electrode. The second electrode is positioned on a second side of the nanochannel opposite the first electrode, and is spaced apart from the first electrode to form an electrode gap that is exposed in the nanochannel. At least a portion of first electrode is movable relative to the second electrode to decrease a size of the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: August 4, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Kim Yang Lee, Thomas Young Chang, David S. Kuo, ShuaiGang Xiao, Xiaomin Yang, Koichi Wago
  • Publication number: 20200240947
    Abstract: A DNA sequencing device and methods of making. The device includes a pair of electrodes having a spacing of no greater than about 2 nm, the electrodes being exposed within a nanopore to measure a DNA strand passing through the nanopore. The device can be made by depositing a conductive layer over a sacrificial channel and then removing the sacrificial channel to form the electrode gap.
    Type: Application
    Filed: April 10, 2020
    Publication date: July 30, 2020
    Inventors: ShuaiGang XIAO, David S. KUO, Xiaomin YANG, Kim Yang LEE, Yautzong HSU, Michael R. FELDBAUM
  • Patent number: 10655164
    Abstract: Apparatus and methods to sequence DNA. A DNA sequencing device includes a passage, a first electrode, and a second electrode. The passage has a width and a length. The first and second electrodes are exposed within the passage and spaced apart from each other to form an electrode gap. The electrode gap is no greater than about 2 nm. The DNA sequencing device is operable to measure with the first and second electrodes a change in electronic signal in response to nucleotides of a DNA strand passing through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 19, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Koichi Wago, ShuaiGang Xiao, Xiaomin Yang, Kim Yang Lee, David S. Kuo, Thomas Young Chang
  • Patent number: 10641726
    Abstract: A DNA sequencing device, and related methods, include a nanopore or nanochannel structure, and a nanoelectrode. The nanoelectrode includes electrode members having free ends exposed within the nanopore or nanochannel structure, an electrode gap defined between of the free ends, and plated portions formed on the free ends to provide a reduced sized for the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 5, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: David S. Kuo, Xiaomin Yang, ShuaiGang Xiao, Kim Yang Lee, Koichi Wago, Thomas Young Chang
  • Patent number: 10640827
    Abstract: A DNA sequencing device, and related methods, include a nanochannel sized to receive a DNA strand, a first electrode member exposed within the nanochannel, and a second electrode member exposed within the nanochannel and spaced apart from the first electrode to form an electrode gap. The second electrode member has a wedge shaped profile, and the first and second electrode members are operable to detect a change in electronic signal as the DNA strand passes through the electrode gap.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 5, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: Kim Yang Lee, David S. Kuo, Thomas Young Chang, Xiaomin Yang, ShuaiGang Xiao, Koichi Wago
  • Patent number: 10564119
    Abstract: A DNA sequencing device includes a first layer having a nanochannel formed therein, and a pair of electrodes arranged vertically relative to each other and spaced apart to define an electrode gap. The electrode gap is exposed in the nanochannel, and the electrode gap is in the range of about 0.3 nm to about 2 nm.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: February 18, 2020
    Assignee: SEAGATE TECHNOLOGY LLC
    Inventors: David S. Kuo, ShuaiGang Xiao, Kim Yang Lee, Xiaomin Yang, Koichi Wago, Thomas Young Chang
  • Patent number: 10529366
    Abstract: A data storage medium may have increased data capacity by being configured with first and second patterned pedestals that are each separated from a substrate by a seed layer. A first polymer brush layer can be positioned between the first and second patterned pedestals atop the seed layer and a second polymer brush layer may be positioned atop each patterned pedestal. The first and second polymer brush layers may be chemically different and a block copolymer can be deposited to self-assemble into separate magnetic domains aligned with either the first or second polymer brush layers.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: January 7, 2020
    Assignee: Seagate Technology LLC
    Inventors: Austin P. Lane, Xiaomin Yang, ShuaiGang Xiao, Kim Yang Lee, David S. Kuo
  • Publication number: 20180294007
    Abstract: A data storage medium may have increased data capacity by being configured with first and second patterned pedestals that are each separated from a substrate by a seed layer. A first polymer brush layer can be positioned between the first and second patterned pedestals atop the seed layer and a second polymer brush layer may be positioned atop each patterned pedestal. The first and second polymer brush layers may be chemically different and a block copolymer can be deposited to self-assemble into separate magnetic domains aligned with either the first or second polymer brush layers.
    Type: Application
    Filed: April 11, 2017
    Publication date: October 11, 2018
    Inventors: Austin P. Lane, Xiaomin Yang, ShuaiGang Xiao, Kim Yang Lee, David S. Kuo