Patents by Inventor Kimber D. Fogelman
Kimber D. Fogelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10279294Abstract: An apparatus, process, and system are disclosed that effectively provide separation of a combined gas/liquid flow stream into its separated gas and liquid factions. The invention is primarily directed to the fields of preparative supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE), but will have other utilization and applicability where phases of dramatically different density, viscosity and volumetric flow require separation.Type: GrantFiled: June 1, 2012Date of Patent: May 7, 2019Assignee: Agilent Technologies, Inc.Inventors: Kimber D Fogelman, Terry A Berger, Edwin E Wikfors
-
Patent number: 9816735Abstract: Methods and systems for pumping compressible fluids in high pressure applications such as high-pressure liquid chromatography (HPLC) or supercritical fluid chromatography (SFC) applications are disclosed. An improved cooling device for a pump head for use in a supercritical fluid chromatography (SFC) system is described. A system for chilling a pumping system, includes a Peltier cooling element in thermal contact with a pump head, wherein the cooling element chills the pump head and a mobile phase fluid flowstream prior to the mobile phase fluid entering the pump; a fluid-cooled heat exchanger, attached to the Peltier cooling element, which removes heat from the cooling element using a circulating fluid; and a second heat exchanger which cools the circulating fluid.Type: GrantFiled: May 20, 2016Date of Patent: November 14, 2017Assignee: Agilent Technologies, Inc.Inventors: Kimber D. Fogelman, Terry A. Berger
-
Publication number: 20160265818Abstract: Methods and systems for pumping compressible fluids in high pressure applications such as high-pressure liquid chromatography (HPLC) or supercritical fluid chromatography (SFC) applications are disclosed. An improved cooling device for a pump head for use in a supercritical fluid chromatography (SFC) system is described. A system for chilling a pumping system, includes a Peltier cooling element in thermal contact with a pump head, wherein the cooling element chills the pump head and a mobile phase fluid flowstream prior to the mobile phase fluid entering the pump; a fluid-cooled heat exchanger, attached to the Peltier cooling element, which removes heat from the cooling element using a circulating fluid; and a second heat exchanger which cools the circulating fluid.Type: ApplicationFiled: May 20, 2016Publication date: September 15, 2016Inventors: Kimber D. Fogelman, Terry A. Berger
-
Patent number: 9163618Abstract: An apparatus, system, and process of converting a standard, high performance liquid chromatography (HPLC) flow path to a flow path suitable for supercritical fluid chromatography (SFC) are described. This reversible technique is applied to a variety of flow configurations including binary, high pressure solvent mixing systems and quaternary, low pressure solvent mixing systems than can be conventionally operated or automated. The technique is generally applied to the fields of supercritical fluid chromatography and high pressure liquid chromatography, but users skilled in the art will find utility for any flow system where pressurization components must be periodically applied to and removed from both ends of a flow stream in an automated manner.Type: GrantFiled: June 22, 2012Date of Patent: October 20, 2015Assignee: Agilent Technologies, Inc.Inventors: Edwin E. Wikfors, Kimber D. Fogelman, Terry A. Berger
-
Patent number: 9114330Abstract: A device includes a gas-liquid separator that receives and separates a biphasic pressurized flow stream and delivers flow to at least one exit port enriched in vapor phase composition and at least one exit port enriched in liquid phase composition. The device further includes a low restriction inlet conduit in communication with the separator exit port enriched in liquid phase composition, and a positive displacement pump having an inlet port in communication with the inlet conduit to receive flow from the gas-liquid separator and an outlet port in communication with an outlet conduit.Type: GrantFiled: September 20, 2011Date of Patent: August 25, 2015Assignee: Agilent Technologies, Inc.Inventors: Kimber D. Fogelman, Edwin E. Wikfors, Terry A. Berger
-
Patent number: 8877051Abstract: A system and process for chromatography that uses a chromatography column to separate components from a sample received into the column in a mobile phase flowstream and places a second chromatography column between a detector and a collection system that compensates the timing of fraction collection for a delay caused by processing the collection signals generated by the detector. The device and process of the preferred and alternative embodiments add a delay into the flowstream of a chromatographic system, such as LC, HPLC, and SFC. Sample fractions are collected from sample component concentration peaks based upon the chromatographic elution of the sample components.Type: GrantFiled: July 21, 2006Date of Patent: November 4, 2014Assignee: Waters Technologies CorporationInventors: Kimber D. Fogelman, Edwin E. Wikfors, Rui Chen
-
Publication number: 20140283688Abstract: An apparatus, process, and system are disclosed that effectively provide separation of a combined gas/liquid flow stream into its separated gas and liquid factions. The invention is primarily directed to the fields of preparative supercritical fluid chromatography [SFC] and supercritical fluid extraction [SFE], but will have other utilization and applicability where phases of dramatically different density, viscosity and volumetric flow require separation.Type: ApplicationFiled: June 1, 2012Publication date: September 25, 2014Inventors: Kimber D. Fogelman, Terry A. Berger, Edwin E. Wikfors
-
Publication number: 20130180404Abstract: An apparatus and process to effectively create an active drain for high and low pressure gas-liquid separator. The invention accomplishes a deterministic drainage rate of variable volume and viscosity liquid fractions from the separator. The mechanisms and methods thereof create a flow path from the separator that dramatically favors controlled liquid flow over a wide range of flow rates and viscosities while restricting gas flow. The invention is a superior method of drainage over conventional systems that employ pressure, vacuum, isolation valves and/or passive flow restrictors to achieve drainage of the separators. The embodiments are primarily directed to the fields of preparative supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE). An advantage of one embodiment allows the economical conversion of typical HPLC systems to state of-the-art supercritical fluid chromatography (SFC) systems with minimal modification to system components.Type: ApplicationFiled: September 20, 2011Publication date: July 18, 2013Applicant: Agilent Technologies, Inc.Inventors: Kimber D. Fogelman, Edwin E. Wikfors, Terry A. Berger
-
Publication number: 20130048095Abstract: An apparatus, system, and process of converting a standard, high performance liquid chromatography (HPLC) flow path to a flow path suitable for supercritical fluid chromatography (SFC) are described. This reversible technique is applied to a variety of flow configurations including binary, high pressure solvent mixing systems and quaternary, low pressure solvent mixing systems than can be conventionally operated or automated. The technique is generally applied to the fields of supercritical fluid chromatography and high pressure liquid chromatography, but users skilled in the art will find utility for any flow system where pressurization components must be periodically applied to and removed from both ends of a flow stream in an automated manner.Type: ApplicationFiled: June 22, 2012Publication date: February 28, 2013Applicant: AURORA SFC SYSTEMS, INC.Inventors: Edwin E. WIKFORS, Kimber D. FOGELMAN, Terry A. BERGER
-
Patent number: 8262760Abstract: A device and process for separating liquid and gas phases in a flowstream containing a liquefied gas or supercritical fluid under pressure mixed with a liquid. A splitter vessel separates the liquid from gas phases and transfers liquid to a collection container while conducting the gas phase out of the splitter. Separation of liquid phase out of the flowstream is provided without additional pressure schemes or solvent extractions imposed on the stream.Type: GrantFiled: January 19, 2011Date of Patent: September 11, 2012Assignee: Waters Technologies Corp.Inventors: Kimber D. Fogelman, Vincent Worley, Peter Sullivan
-
Patent number: 8215922Abstract: An invention is claimed that enables the pumping of compressible fluids at high pressures when an accurate flow is desired. Two pressure sources, for example pumps plumbed in series, separate thermodynamic work, such as pressurization, at the first pressure source from a volumetric or matter metering function in the second pressure source. One example is a flowstream delivery for a chemical instrumentation system that is manufactured from relatively unsophisticated pumps yet delivers precise flows with low pulsation (<1%) over pressures greater than 100 bar. An advantage of one embodiment allows the economical conversion of typical HPLC systems to state of-the-art supercritical fluid chromatography (SFC) systems with minimal modification to system components.Type: GrantFiled: September 5, 2008Date of Patent: July 10, 2012Assignee: Aurora SFC Systems, Inc.Inventors: Terry A. Berger, Kimber D. Fogelman, Edwin E. Wikfors, L. Thomson Staats, III, Samuel O. Colgate, Michael A. Casale
-
Patent number: 7964029Abstract: A device and process for separating liquid and gas phases in a flowstream containing a liquefied gas or supercritical fluid under pressure mixed with a liquid. A splitter vessel separates the liquid from gas phases and transfers liquid to a collection container while conducting the gas phase out of the splitter. Separation of liquid phase out of the flowstream is provided without additional pressure schemes or solvent extractions imposed on the stream.Type: GrantFiled: July 17, 2006Date of Patent: June 21, 2011Assignee: Thar Instrument, Inc.Inventors: Kimber D. Fogelman, Vincent Worley, Peter Sullivan
-
Publication number: 20110113962Abstract: A device and process for separating liquid and gas phases in a flowstream containing a liquefied gas or supercritical fluid under pressure mixed with a liquid. A splitter vessel separates the liquid from gas phases and transfers liquid to a collection container while conducting the gas phase out of the splitter. Separation of liquid phase out of the flowstream is provided without additional pressure schemes or solvent extractions imposed on the stream.Type: ApplicationFiled: January 19, 2011Publication date: May 19, 2011Inventors: Kimber D. Fogelman, Vincent Worley, Peter Sullivan
-
Patent number: 7905133Abstract: A splitter for a pressurized primary flowstream of a mobile phase is provided. The splitter comprises a first splitting stage that divides the primary flowstream between a major split flowstream and a minor split flowstream by means of a first and a second restrictive flow element; a first dilution stage that combines a dilution flow source with the minor split flowstream to create a diluted minor flowstream; a second splitting stage that divides the diluted minor flowstream between a secondary major diluted flowstream and a secondary minor diluted flowstream by means of a third restrictive element in the secondary minor diluted flow stream; and a second dilution stage wherein a conditioning flow source conditions the secondary minor diluted flow stream after the third restrictive element prior to outlet of the secondary minor diluted flowstream from the splitter.Type: GrantFiled: May 16, 2008Date of Patent: March 15, 2011Assignee: Thar Instruments, Inc.Inventors: Lalit Chordia, Kimber D. Fogelman, Edwin E. Wickfors, James L. Waters
-
Patent number: 7670487Abstract: A depressurization process for a packed separation column is provided where the column system experiences a rapid and/or severe drop in pressure that could potentially damage column components. The process provides a safe de-pressurization of the column on the outlet side by decreasing the outlet pressure in controlled steps while allowing the inlet pressure of the column time to lower after each decreased step.Type: GrantFiled: July 21, 2006Date of Patent: March 2, 2010Inventors: Edwin E. Wikfors, Kimber D. Fogelman
-
Publication number: 20100040483Abstract: An invention is claimed that enables the pumping of compressible fluids at high pressures when an accurate flow is desired. Two pressure sources, for example pumps plumbed in series, separate thermodynamic work, such as pressurization, at the first pressure source from a volumetric or matter metering function in the second pressure source. One example is a flowstream delivery for a chemical instrumentation system that is manufactured from relatively unsophisticated pumps yet delivers precise flows with low pulsation (<1 %) over pressures greater than 100 bar. An advantage of one embodiment allows the economical conversion of typical HPLC systems to state of-the-art supercritical fluid chromatography (SFC) systems with minimal modification to system components.Type: ApplicationFiled: September 5, 2008Publication date: February 18, 2010Inventors: Terry A. Berger, Kimber D. Fogelman, Edwin E. Wikfors, L. Thomson Staats, III, Samuel O. Colgate, Michael A. Casale
-
Publication number: 20090165873Abstract: A splitter for a pressurized primary flowstream of a mobile phase is provided. The splitter comprises a first splitting stage that divides the primary flowstream between a major split flowstream and a minor split flowstream by means of a first and a second restrictive flow element; a first dilution stage that combines a dilution flow source with the minor split flowstream to create a diluted minor flowstream;a second splitting stage that divides the diluted minor flowstream between a secondary major diluted flowstream and a secondary minor diluted flowstream by means of a third restrictive element in the secondary minor diluted flow stream; and a second dilution stage wherein a conditioning flow source conditions the secondary minor diluted flow stream after the third restrictive element prior to outlet of the secondary minor diluted flowstream from the splitter.Type: ApplicationFiled: May 16, 2008Publication date: July 2, 2009Inventors: Lalit Chordia, Kimber D. Fogelman, Edwin E. Wickfors, James L. Waters
-
Publication number: 20090050568Abstract: A system and process for chromatography that uses a chromatography column to separate components from a sample received into the column in a mobile phase flowstream and places a second chromatography column between a detector and a collection system that compensates the timing of fraction collection for a delay caused by processing the collection signals generated by the detector. The device and process of the preferred and alternative embodiments add a delay into the flowstream of a chromatographic system, such as LC, HPLC, and SFC. Sample fractions are collected from sample component concentration peaks based upon the chromatographic elution of the sample components.Type: ApplicationFiled: July 21, 2006Publication date: February 26, 2009Inventors: Kimber D. Fogelman, Edwin E. Wikfors, Rui Chen
-
Publication number: 20080021663Abstract: A depressurization process for a packed separation column is provided where the column system experiences a rapid and/or severe drop in pressure that could potentially damage column components. The process provides a safe de-pressurization of the column on the outlet side by decreasing the outlet pressure in controlled steps while allowing the inlet pressure of the column time to lower after each decreased step.Type: ApplicationFiled: July 21, 2006Publication date: January 24, 2008Inventors: Edwin E. Wikfors, Kimber D. Fogelman
-
Publication number: 20080010956Abstract: A device and process for separating liquid and gas phases in a flowstream containing a liquefied gas or supercritical fluid under pressure mixed with a liquid. A splitter vessel separates the liquid from gas phases and transfers liquid to a collection container while conducting the gas phase out of the splitter. Separation of liquid phase out of the flowstream is provided without additional pressure schemes or solvent extractions imposed on the stream.Type: ApplicationFiled: July 17, 2006Publication date: January 17, 2008Inventors: Kimber D. Fogelman, Vincent Worley, Peter Sullivan