Patents by Inventor Kimberly A. Dodd

Kimberly A. Dodd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rift valley fever virus replicon particles and use thereof
    Patent number: 9687542
    Abstract: Disclosed herein is a robust system for the reverse genetics generation of a Rift Valley fever (RVF) virus replicon particle (VRPRVF) vaccine candidate. VRPRVF can actively synthesize viral RNA and proteins, but lack structural glycoprotein genes, preventing spread within immunized individuals and reducing the risk of vaccine-induced pathogenicity. Is it disclosed herein that VRPRVF immunization is both safe and efficacious, resulting in a robust immune response that is protective against RVF virus challenge within 24 hours of immunization. Provided herein are VRPRVF, methods of producing VRPRVF, and method of using VRPRVF for immunization against RVF virus infection.
    Type: Grant
    Filed: June 18, 2013
    Date of Patent: June 27, 2017
    Assignee: The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Kimberly A. Dodd, Brian H. Bird, Cesar G. Albarino, Stuart T. Nichol
  • RIFT VALLEY FEVER VIRUS REPLICON PARTICLES AND USE THEREOF
    Publication number: 20150196630
    Abstract: Disclosed herein is a robust system for the reverse genetics generation of a Rift Valley fever (RVF) virus replicon particle (VRPRVF) vaccine candidate. VRPRVF can actively synthesize viral RNA and proteins, but lack structural glycoprotein genes, preventing spread within immunized individuals and reducing the risk of vaccine-induced pathogenicity. Is it disclosed herein that VRPRVF immunization is both safe and efficacious, resulting in a robust immune response that is protective against RVF virus challenge within 24 hours of immunization. Provided herein are VRPRVF, methods of producing VRPRVF, and method of using VRPRVF for immunization against RVF virus infection.
    Type: Application
    Filed: June 18, 2013
    Publication date: July 16, 2015
    Inventors: Kimberly A. Dodd, Brian H. Bird, Cesar G. Albarino, Stuart T. Nichol