Patents by Inventor Kimberly A. Hunsucker

Kimberly A. Hunsucker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of 4-amino-thalidomide enantiomers
    Patent number: 8153806
    Abstract: The invention provides new and useful analogs of 4-amino-thalidomide. These analogs include S(?)-4-amino-thalidomide and R(+)-4-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: April 10, 2012
    Assignee: The Children's Medical Center Corporation
    Inventors: Anthony Treston, Jamshed H. Shah, Robert J. D'Amato, Kimberly A. Hunsucker, John Rougas, Barry P. Conner, Victor Pribdula, Glenn M. Swartz
  • SYNTHESIS OF 4-AMINO-THALIDOMIDE ENANTIOMERS
    Publication number: 20100280249
    Abstract: The invention provides new and useful analogs of 4-amino-thalidomide. These analogs include S(?)-4-amino-thalidomide and R(+)-4-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.
    Type: Application
    Filed: July 16, 2010
    Publication date: November 4, 2010
    Inventors: Anthony Treston, Jamshed H. Shah, Robert J. D'Amato, Kimberly A. Hunsucker, John Rougas, Barry P. Conner, Victor Pribdula, Glenn M. Swartz
  • Method of synthesis of 4-amino-thalidomide enantiomers
    Patent number: 7812169
    Abstract: The invention provides new and useful analogs of 4-amino-thalidomide. These analogs include S(?)-4-amino-thalidomide and R(+)-4-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: October 12, 2010
    Assignee: The Children's Medical Center Corporation
    Inventors: Anthony Treston, Jamshed H. Shah, Robert J. D'Amato, Kimberly A. Hunsucker, John Rougas, Barry P. Conner, Victor Pribdula, Glenn M. Swartz
  • Methods for treating macular degeneration using 4-(amino)-2-(2,6-dioxo(3-piperidyle))-isoindoline-1,3-dione
    Publication number: 20080306113
    Abstract: Methods of treating, preventing and/or managing macular degeneration are disclosed. Specific embodiments encompass the administration of 4-(amino)-2-(2,6-dioxo(3-piperidyl))-isoindoline-1,3-dione, or a pharmaceutically acceptable salt, solvate or stereoisomer thereof, alone or in combination with a second active agent and/or surgery.
    Type: Application
    Filed: April 22, 2008
    Publication date: December 11, 2008
    Inventors: Anthony Treston, Jamshed H. Shah, Robert J. D'Amato, Kimberly A. Hunsucker, John Rougas, Barry P. Conner, Victor Pribdula, Glenn M. Swartz
  • Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
    Publication number: 20070105903
    Abstract: The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substituted thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
    Type: Application
    Filed: August 29, 2006
    Publication date: May 10, 2007
    Inventors: Anthony Treston, Jamshed Shah, Robert D'Amato, Barry Conner, Kimberly Hunsucker, John Rougas, Glenn Swartz, Victor Pribluda
  • Use of nitrogen substituted thalidomide analogs for the treatment of macular degenerator
    Patent number: 7153867
    Abstract: The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substituted thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: December 26, 2006
    Assignee: Celgene Corporation
    Inventors: Jamshed H. Shah, Barry P. Conner, Glenn M. Swartz, Kimberly A. Hunsucker, John Rougas, Robert J. D'Amato, Victor Pribluda, Anthony Treston
  • Antiangiogenic agents
    Patent number: 7135581
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the specification.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: November 14, 2006
    Assignee: Entremed, Inc.
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Victor S. Pribluda, Theresa M. LaVallee, Shawn J. Green, Christopher J. Herbstritt, Xiaoguo H. Zhan, Anthony M. Treston
  • Antiangiogenic agents
    Publication number: 20050192258
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the specification.
    Type: Application
    Filed: April 29, 2005
    Publication date: September 1, 2005
    Inventors: Gregory Agoston, Jamshed Shah, Kimberly Hunsucker, Victor Pribluda, Theresa LaVallee, Shawn Green, Christopher Herbstritt, Xiaoguo Zhan, Anthony Treston
  • Synthesis of 3-amino-thalidomide and its enantiomers
    Publication number: 20040147558
    Abstract: The invention provides new and useful analogs of 3-amino-thalidomide. These analogs include S(−)-3-amino-thalidomide and R(+)-3-amino-thalidomide. The invention also provides processes for making these analogs. Further, the invention provides methods for inhibiting angiogenesis and treating angiogenesis-associated diseases, including cancer and macular degeneration, by administering these compounds.
    Type: Application
    Filed: March 11, 2004
    Publication date: July 29, 2004
    Inventors: Anthony Treston, Jamshed H Shah, Robert J D'Amato, Kimberly A Hunsucker, John Rougas, Barry P Conner, Victor Pribdula, Glenn M Swartz
  • Non-steroidal analogs of 2-methoxyestradiol
    Publication number: 20030236439
    Abstract: Compounds, compositions, and methods for treating disease states characterized by undesirable angiogenesis, proliferative activity, or cell mitosis by administering non-steroidal analogs of 2-methoxyestradiol of the general formula: 1
    Type: Application
    Filed: January 30, 2003
    Publication date: December 25, 2003
    Inventors: Gregory Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Anthony M. Treston, Victor S. Pribluda
  • Non-steroidal analogs of 2-methoxyestradiol
    Publication number: 20030187076
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis and proliferative activity by administering non-steroidal derivatives of 2-methoxyestradiol of the general formula: 1
    Type: Application
    Filed: January 30, 2003
    Publication date: October 2, 2003
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Anthony M. Treston, Victor S. Pribluda
  • Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
    Publication number: 20030139451
    Abstract: The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substituted thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
    Type: Application
    Filed: August 6, 2002
    Publication date: July 24, 2003
    Inventors: Jamshed H. Shah, Barry P. Conner, Glenn M. Swartz, Kimberly A. Hunsucker, John Rougas, Robert J. D'Amato, Victor Pribluda, Anthony Treston
  • Antiangiogenic agents
    Publication number: 20020082433
    Abstract: Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: 1
    Type: Application
    Filed: August 24, 2001
    Publication date: June 27, 2002
    Inventors: Gregory E. Agoston, Jamshed H. Shah, Kimberly A. Hunsucker, Victor S. Pribluda, Theresa M. LaVallee, Shawn J. Green, Christopher J. Herbstritt, Xiaoguo H. Zhan, Anthony M. Treston