Patents by Inventor Kimberly B. White

Kimberly B. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzimidazolone peptidomimetics as thrombin receptor antagonists
    Patent number: 6943149
    Abstract: The invention is directed to novel benzimidazolone peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, Angiogenesis related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted benzimidazolone peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: September 13, 2005
    Assignees: Ortho McNeil Pharmaceutical, Inc., Millennium Pharmaceuticals, Inc.
    Inventors: Han-Cheng Zhang, Bruce E. Maryanoff, David F. McComsey, Kimberly B. White
  • Macroheterocylic compounds useful as kinase inhibitors
    Patent number: 6828327
    Abstract: This invention is directed to macroheterocyclic compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: December 7, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Gee-Hong Kuo, Han-Cheng Zhang, Catherine Prouty, Alan DeAngelis, Peter Connolly, William V. Murray, Lan Shen, Bruce Conway, Keith Demarest, Chandra R. Shah, Bruce E. Maryanoff, Kimberly B. White
  • Novel benzimidazolone peptidomimetics as thrombin receptor antagonists
    Publication number: 20040063642
    Abstract: The invention is directed to novel benzimidazolone peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, Angiogenesis related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted benzimidazolone peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Application
    Filed: March 17, 2003
    Publication date: April 1, 2004
    Inventors: Han-Cheng Zhang, Bruce E. Maryanoff, David F. McComsey, Kimberly B. White
  • Benzimidazolone peptidometics as thrombin receptor antagonist
    Patent number: 6630451
    Abstract: The invention is directed to novel benzimidazolone peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, Angiogenesis related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted benzimidazolone peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: October 7, 2003
    Assignee: OrthoMcNeil Pharmaceutical, Inc.
    Inventors: Han-Cheng Zhang, Bruce E. Maryanoff, David F. McComsey, Kimberly B. White
  • Macroheterocylic compounds useful as kinase inhibitors
    Publication number: 20030078280
    Abstract: This invention is directed to macroheterocyclic compounds useful as kinase or dual-kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase or dual-kinase mediated disorder.
    Type: Application
    Filed: December 6, 2001
    Publication date: April 24, 2003
    Inventors: Gee-Hong Kuo, Han-Cheng Zhang, Catherine Prouty, Alan DeAngelis, Peter Connolly, William V. Murray, Lan Shen, Bruce Conway, Keith Demarest, Chandra R. Shah, Bruce E. Maryanoff, Kimberly B. White