Patents by Inventor Kimberly Brown

Kimberly Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Holder device for dental x-ray digital sensor
    Publication number: 20070121789
    Abstract: A sensor holder (10) includes a frame member (20) that bounds a void area (21) and which is configured to receive a sensor (11). A retaining means (50, 51) is provided to hold the sensor (11) to the frame (20) such that a connecting cable (12) affixed to the sensor (11) is secured and positioned by the void area (21) for a subsequent imaging procedure.
    Type: Application
    Filed: August 16, 2006
    Publication date: May 31, 2007
    Applicant: Dentsply Research and Development Corp.
    Inventors: John Steck, Kimberly Brown, Nicole Sullivan
  • Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Patent number: 7220565
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: May 22, 2007
    Assignee: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Alfredo Lopez De Leon, Sandra Merino
  • Polypeptides having phospholipase B activity and nucleic acids encoding same
    Publication number: 20060252126
    Abstract: The present invention relates to isolated polypeptides having phospholipase B activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: July 18, 2006
    Publication date: November 9, 2006
    Applicant: Novozymes, Inc.
    Inventors: Paul Harris, Kimberly Brown
  • Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
    Publication number: 20060218671
    Abstract: The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: January 6, 2006
    Publication date: September 28, 2006
    Applicant: Novozymes, Inc.
    Inventors: Kimberly Brown, Paul Harris, Alfredo Lopez De Leon, Sandra Merino
  • Polypeptides having dipeptidyl aminopeptidase activity and nucleic acids encoding same
    Patent number: 7098001
    Abstract: The present invention relates to isolated polypeptides having dipeptidyl aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: August 29, 2006
    Assignee: Novozymes, Inc.
    Inventors: Alexandeer Blinkovsky, Kimberly Brown, Michael W. Rey, Alan Klotz, Tony Byun
  • Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
    Publication number: 20060156437
    Abstract: The present invention relates to isolated polypeptides having alpha-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: July 6, 2005
    Publication date: July 13, 2006
    Applicant: Novozymes, Inc.
    Inventors: Debbie Yaver, Janine Lin, Alexander Blinkovsky, Kimberly Brown, Michael Rey
  • Polypeptides having cellulolytic enhancing activity andpolynucleotides encoding same
    Publication number: 20050191736
    Abstract: The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: January 28, 2005
    Publication date: September 1, 2005
    Applicant: Novozymes Biotech, Inc.
    Inventors: Kimberly Brown, Paul Harris, Elizabeth Zaretsky, Edward Re, Elena Vlasenko, Keith McFarland, Alfredo Lopez de Leon
  • Polypeptides having aminopeptidase activity and nucleic acids encoding same
    Publication number: 20050118610
    Abstract: The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: June 30, 2004
    Publication date: June 2, 2005
    Applicant: Novozymes Bioech, Inc.
    Inventors: Alexander Blinkovsky, Kimberly Brown, Elizabeth Golightly, Tony Byun, Lene Kofod
  • Microbial trypsin mutants having chymotrypsin activity and nucleic acids encoding same
    Publication number: 20050037368
    Abstract: The present invention relates to microbial trypsin variants having chymotrypsin-like activity, comprising: (a) a one or more substitutions corresponding to positions 144, S193A, 198, 201, 218, 223, 227, 228, 229, 230, and 231 of amino acids 25 to 248 of SEQ ID NO: 2, (b) one or more deletions corresponding to positions 192, 197, and 226 of amino acids 25 to 248 of SEQ ID NO: 2; and (c) an insertion between positions corresponding to positions 224 and 225 of amino acids 25 to 248 of SEQ ID NO: 2. The present invention further relates to nucleotide sequences encoding microbial trypsin variants having chymotrypsin-like activity; nucleic acid constructs, expression vectors, and recombinant host cells comprising such nucleotide sequences; and methods of producing microbial trypsin variants having chymotrypsin-like activity or a precursor thereof.
    Type: Application
    Filed: September 24, 2003
    Publication date: February 17, 2005
    Applicant: Novozymes Biotech, Inc.
    Inventors: Alan Klotz, Kimberly Brown, Elizabeth Zaretsky
  • Polypeptides having aminopeptidase activity and nucleic acids encoding same
    Patent number: 6800467
    Abstract: The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: October 5, 2004
    Assignee: Novozymes Biotech, Inc.
    Inventors: Alexander Blinkovsky, Kimberly Brown, Elizabeth Golightly, Tony Byun
  • Polypeptides having dipeptidyl aminopeptidase activity and nucleic acids encoding same
    Publication number: 20040171104
    Abstract: The present invention relates to isolated polypeptides having dipeptidyl aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: November 25, 2003
    Publication date: September 2, 2004
    Applicant: Novozymes Biotech, Inc.
    Inventors: Alexander Blinkovsky, Kimberly Brown, Michael W. Rey, Alan Klotz, Tony Byun
  • Methods for producing mammalian trypsins
    Publication number: 20040043455
    Abstract: The present invention relates to methods for producing a mammalian trypsin in a Fusarium venenatum host strain, the method comprising (a) cultivating the Fusarium venenatum host strain in a culture medium under conditions suitable for expression of the mammalian trypsin and secretion thereof into the medium, wherein the Fusarium venenatum host strain comprises a nucleic acid construct comprising a nucleic acid sequence encoding the mature coding sequence of a mammalian trypsin operably linked to nucleotides 58 to 129 of SEQ ID NO: 1 encoding the signal peptide and propeptide of Fusarium oxysporum trypsinogen; and (b) recovering the mammalian trypsin from the medium.
    Type: Application
    Filed: August 29, 2003
    Publication date: March 4, 2004
    Applicant: Novozymes Biotech, Inc.
    Inventors: Randy Berka, Kimberly Brown
  • Promoters for expressing genes in a fungal cell
    Patent number: 6692940
    Abstract: The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO. 1, nucleotides 1 to 938 of SEQ ID NO. 2, and nucleotides 1 to 3060 of SEQ ID NO. 3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: February 17, 2004
    Assignee: Novozymes Biotech, Inc.
    Inventors: Randy M. Berka, Michael W. Rey, Kimberly Brown, Stephen H. Brown
  • Polypeptides having aminopeptidase activity and nucleic acids encoding same
    Patent number: 6673571
    Abstract: The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: January 6, 2004
    Assignee: Novozymes Biotech, Inc.
    Inventors: Alexander Blinkovsky, Tony S. Byun, Alan V. Klotz, Alan Sloma, Kimberly Brown, Maria Tang, Mikio Fujii, Chigusa Marumoto, Lene Venke Kofod
  • Polypeptides having dipeptidyl aminopeptidase activity and nucleic acids encoding same
    Patent number: 6664092
    Abstract: The present invention relates to isolated polypeptides having dipeptidyl aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: December 16, 2003
    Assignee: Novozymes Biotech, Inc.
    Inventors: Alexander Blinkovsky, Kimberly Brown, Michael W. Rey, Alan Klotz, Tony Byun
  • Promoters for expressing genes in a fungal cell
    Publication number: 20030148452
    Abstract: The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO. 1, nucleotides 1 to 938 of SEQ ID NO. 2, and nucleotides 1 to 3060 of SEQ ID NO. 3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.
    Type: Application
    Filed: October 28, 2002
    Publication date: August 7, 2003
    Applicant: Novozymes Biotech, Inc.
    Inventors: Randy M. Berka, Michael W. Rey, Kimberly Brown, Stephen H. Brown
  • Promoters for expressing genes in a fungal cell
    Patent number: 6518044
    Abstract: The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO:1, nucleotides 1 to 938 of SEQ ID NO:2, and nucleotides 1 to 3060 of SEQ ID NO:3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: February 11, 2003
    Assignee: Novozymes Biotech, Inc.
    Inventors: Randy M. Berka, Michael W. Rey, Kimberly Brown, Stephen H. Brown
  • Polypeptides having aminopeptidase activity and nucleic acids encoding same
    Publication number: 20020177210
    Abstract: The present invention relates to isolated polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing and using the polypeptides.
    Type: Application
    Filed: September 19, 2001
    Publication date: November 28, 2002
    Applicant: Novozymes Biotech, Inc.
    Inventors: Alexander Blinkovsky, Tony S. Byun, Alan V. Klotz, Alan Sloma, Kimberly Brown, Maria Tang, Mikio Fujii, Chigusa Marumoto, Lene Venke Kofod
  • Methods of producing protein hydrolysates
    Patent number: 6465209
    Abstract: The present invention relates to methods of producing protein hydrolysates, comprising adding to a proteinaceous material one or more aminopeptidase(s) having glycine releasing properties and one or more additional proteases wherein the amount of glycine produced is greater than the amount of glycine produced by the one or more additional proteases alone under the same conditions.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: October 15, 2002
    Assignees: Novozymes Biotech, Inc., Novozymes A/S, Japan Tobacco, Inc.
    Inventors: Alexander Blinkovsky, Kimberly Brown, Elizabeth Golightly, Tony Byun, Thomas E. Mathiasen, Lene V. Kofod, Mikio Fujii, Chigusa Marumoto
  • Promoters for expressing genes in a fungal cell
    Patent number: 6361973
    Abstract: The present invention relates to methods for producing a polypeptide, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first nucleic acid sequence encoding the polypeptide operably linked to a second nucleic acid sequence comprising a promoter foreign to the nucleic acid sequence, wherein the promoter comprises a sequence selected from the group consisting of nucleotides 1 to 3949 of SEQ ID NO:1, nucleotides 1 to 938 of SEQ ID NO:2, and nucleotides 1 to 3060 of SEQ ID NO:3, and a subsequence thereof; and mutant, hybrid, and tandem promoters thereof; and (b) isolating the polypeptide from the cultivation medium. The present invention also relates to the isolated promoter sequences and to constructs, vectors, and fungal host cells comprising the promoter sequences operably linked to nucleic acid sequences encoding polypeptides.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: March 26, 2002
    Assignee: Novozymes Biotech, Inc.
    Inventors: Randy M. Berka, Michael W. Rey, Kimberly Brown, Stephen H. Brown