Patents by Inventor Kimberly C. Brisack

Kimberly C. Brisack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apatite in-situ restoration
    Patent number: 10099157
    Abstract: Disclosed are compositions and methods for regenerating or reducing the deterioration of an apatite solid surface during, or subsequent to, a chromatographic procedure for purifying a target molecule from a sample, by treating the apatite solid surface with a buffered calcium solution, followed by a phosphate buffered solution, followed by an alkaline hydroxide. The buffered calcium solution, phosphate buffered solution, and alkaline hydroxide can be applied subsequent to a bind and elute or flow through purification procedure. The methods provide an increase in resin mass and/or particle strength compared to prior methods.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 16, 2018
    Assignee: Bio-Rad Laboratories, Inc.
    Inventors: Mark A. Snyder, Kimberly C. Brisack
  • Apatite In-Situ Restoration
    Publication number: 20150367252
    Abstract: Disclosed herein are methods of regenerating apatite surfaces, for example after purification of a target analyte.
    Type: Application
    Filed: June 23, 2015
    Publication date: December 24, 2015
    Inventors: Mark A. Snyder, Kimberly C. Brisack