Patents by Inventor Kimberly Carr Ferguson

Kimberly Carr Ferguson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100112566
    Abstract: Human VIPR1 genes are identified as modulators of the E2F/RB pathway, and thus are therapeutic targets for disorders associated with defective E2F/RB function. Methods for identifying modulators of E2F/RB, comprising screening for agents that modulate the activity of VIPR1 are provided.
    Type: Application
    Filed: September 24, 2007
    Publication date: May 6, 2010
    Inventors: Kyle A. Edgar, Kimberly Carr Ferguson, Monique Nicoll, Christopher G. Winter
  • Patent number: 6781028
    Abstract: Drosophila melanogaster and C. elegans that have been genetically modified to express or mis-express proteins involved in the sterol regulatory element binding protein (SREBP) pathway are described. These genetically modified animal models have identifiable phenotypes that make them useful in assays for studying lipid metabolism, other genes implicated in lipid metabolism, and compounds capable of modulating lipid metabolism pathways. Methods for studying lipid metabolism in living nematodes using fluorescently-labelled fatty acid conjugates, such BODITY™ fatty acid conjugates, are also described. Novel SREBP pathway nucleic acid and protein sequences are also described.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: August 24, 2004
    Assignee: Exelixis, Inc.
    Inventors: Michael R. Costa, Stephen K. Doberstein, Sarah L. Elson, Kimberly Carr Ferguson, Sheila Akiko Homburger
  • Publication number: 20030187246
    Abstract: The present invention relates to C. elegans insulin-like genes and methods for identifying insulin-like genes. The methods provide nucleotide sequences of C. elegans insulin-like genes, amino acid sequences of their encoded proteins, and derivatives (e.g., fragments) and analogs thereof. The invention further relates to fragments (and derivatives and analogs thereof) of insulin-like proteins which comprise one or more domains of an insulin-like protein. Antibodies to an insulin-like protein, and derivatives and analogs thereof, are provided. Methods of production of an insulin-like protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Further, methods to identify the biological function of a C. elegans insulin-like gene are provided, including various methods for the functional modification (e.g., overexpression, underexpression, mutation, knock-out) of one or more genes simultaneously. Still further, methods to identify a C.
    Type: Application
    Filed: January 9, 2003
    Publication date: October 2, 2003
    Inventors: Stephen Kohl Doberstein, Andrew Roy Buchman, Kimberly Carr Ferguson, Sheila Akiko Homburger, Darren Mark Platt
  • Patent number: 6627746
    Abstract: The present invention relates to C. elegans insulin-like genes and methods for identifying insulin-like genes. The methods provide nucleotide sequences of C. elegans insulin-like genes, amino acid sequences of their encoded proteins, and derivatives (e.g., fragments) and analogs thereof. The invention further relates to fragments (and derivatives and analogs thereof) of insulin-like proteins which comprise one or more domains of an insulin-like protein. Antibodies to an insulin-like protein, and derivatives and analogs thereof, are provided. Methods of production of an insulin-like protein (e.g., by recombinant means), and derivatives and analogs thereof, are provided. Further, methods to identify the biological function of a C. elegans insulin-like gene are provided, including various methods for the functional modification (e.g., overexpression, underexpression, mutation, knock-out) of one or more genes simultaneously. Still further, methods to identify a C.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: September 30, 2003
    Assignee: Exelixis, Inc.
    Inventors: Stephen Kohl Doberstein, Darren Mark Platt, Kimberly Carr Ferguson, Andrew Roy Buchman, Sheila Akiko Homburger