Abstract: The present invention relates to a novel catheter brush device. The device is designed to offer a more effective method of removing blood clots and debris from the bladder without requiring additional surgery. The device comprises a brush with a blunt end with soft bristles, as well as a loop end that acts as a handle. Users remove the drainage tube from the catheter and insert the brush through the opening to the tip of the catheter. The brush is then moved in a gentle, circular motion to clear any clotting and blockages from the catheter. The brush is then removed, and the drainage tube reattached, such that urine can flow freely through the catheter. If sterility is maintained, process may be repeated as needed.

Abstract: Provided are systems, constructs, genetically modified organisms, and methods for creating transgenic rodent research and commercial models of human physiology, disease, syndromes, and disorders. Provided are genetically modified rodents encoding for an sgRNA useful in a Cas9-mediated split gene-drive system for optimization of the gene drive system in rodents.

Abstract: Method and apparatus for facilitating virtual object selection and interaction in a computer-generated environment such as a virtual or augmented reality 3-D environment are disclosed. A physical controller allows interaction by the user with a tool displayed at a first position in the computer-generated environment where, when a first signal is received from the physical controller to initiate selection of the tool, a visual cue is created in the computer-generated environment. The visual cue includes a vector that allows targeting of the tool and is displayed with respect to a virtual controller that is a graphical representation of the physical controller in the computer-generated environment. Upon receipt of a selection signal from the physical controller when the vector and the tool intersect, the computer-generated environment is updated to display the tool at a second location that is relative to the virtual controller.

Abstract: Method and apparatus for facilitating virtual object selection and interaction in a computer-generated environment such as a virtual or augmented reality 3-D environment are disclosed. A physical controller allows interaction by the user with a tool displayed at a first position in the computer-generated environment where, when a first signal is received from the physical controller to initiate selection of the tool, a visual cue is created in the computer-generated environment. The visual cue includes a vector that allows targeting of the tool and is displayed with respect to a virtual controller that is a graphical representation of the physical controller in the computer-generated environment. Upon receipt of a selection signal from the physical controller when the vector and the tool intersect, the computer-generated environment is updated to display the tool at a second location that is relative to the virtual controller.