Patents by Inventor Kimberly Jayne GASPAR

Kimberly Jayne GASPAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody-urease conjugates for therapeutic purposes
    Patent number: 11931422
    Abstract: Pharmaceutical compositions comprising antibody-urease conjugates and substantially free of unconjugated urease are disclosed. These compositions are prepared by a method that does not require chromatographic purification. These pharmaceutical compositions have utility in the treatment of cancer by antibody-directed enzyme prodrug therapy wherein the urease converts endogenous urea into ammonia in situ to induce cytotoxicity.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: March 19, 2024
    Assignee: HELIX BIOPHARMA CORPORATION
    Inventors: Heman Chao, Wah Yau Wong, Baomin Tian, Kimberly Jayne Gaspar, Praveen Kumar
  • ANTIBODY-UREASE CONJUGATES FOR THERAPEUTIC PURPOSES
    Publication number: 20180000963
    Abstract: Pharmaceutical compositions comprising antibody-urease conjugates and substantially free of unconjugated urease are disclosed. These compositions are prepared by a method that does not require chromatographic purification. These pharmaceutical compositions have utility in the treatment of cancer by antibody-directed enzyme prodrug therapy wherein the urease converts endogenous urea into ammonia in situ to induce cytotoxicity.
    Type: Application
    Filed: January 22, 2016
    Publication date: January 4, 2018
    Applicant: HELIX BIOPHARMA CORPORATION
    Inventors: Heman CHAO, Wah Yau WONG, Baomin TIAN, Kimberly Jayne GASPAR, Praveen KUMAR