Patents by Inventor Kimberly K. Knoche

Kimberly K. Knoche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymerase inhibitors and related compositions and methods
    Patent number: 11939310
    Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.
    Type: Grant
    Filed: October 25, 2022
    Date of Patent: March 26, 2024
    Assignee: Promega Corporation
    Inventors: Wenhui Zhou, Kimberly K. Knoche, Douglas R. Storts, Min Zhou, Poncho Meisenheimer
  • POLYMERASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20230097403
    Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.
    Type: Application
    Filed: October 25, 2022
    Publication date: March 30, 2023
    Inventors: Wenhui Zhou, Kimberly K. Knoche, Douglas R. Storts, Min Zhou, Poncho Meisenheimer
  • Polymerase inhibitors and related compositions and methods
    Patent number: 11524946
    Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: December 13, 2022
    Assignee: Promega Corporation
    Inventors: Wenhui Zhou, Kimberly K. Knoche, Douglas R. Storts, Min Zhou, Poncho Meisenheimer
  • POLYMERASE INHIBITORS AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20200199088
    Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.
    Type: Application
    Filed: December 12, 2019
    Publication date: June 25, 2020
    Inventors: Wenhui Zhou, Kimberly K. Knoche, Douglas R. Storts, Min Zhou, Poncho Meisenheimer
  • Isolated agarase enzyme from flavobacterium SP. strain NR19, cloned genes therefor, and expression thereof in transformed host cells
    Patent number: 6001636
    Abstract: Novel purified agarase enzymes from Flavobacterium sp. strain NR19 and cloned genes encoding the agarase enzymes are disclosed. Transformed host cells which express the novel agarase enzymes in isolatable quantities are also described. Also disclosed are antibodies specifically reactive with the novel agarases.
    Type: Grant
    Filed: June 30, 1998
    Date of Patent: December 14, 1999
    Assignee: Promega Corporation
    Inventors: Mark W. Knuth, Kimberly K. Knoche, Susanne Selman, James R. Hartnett
  • Isolated agarase enzyme from flavobacterium sp. strain NR19, cloned genes therefor, and expression thereof in transformed host cells
    Patent number: 5869310
    Abstract: Novel purified agarase enzymes from Flavobacterium sp. strain NR19 and cloned genes encoding the agarase enzymes are disclosed. Transformed host cells which express the novel agarase enzymes in isolatable quantities are also described. Also disclosed are antibodies specifically reactive with the novel agarases.
    Type: Grant
    Filed: June 3, 1996
    Date of Patent: February 9, 1999
    Assignee: Promega Corporation
    Inventors: Mark W. Knuth, Kimberly K. Knoche, Susanne Selman, James R. Hartnett