Patents by Inventor Kimberly M. L. May

Kimberly M. L. May has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7595149
    Abstract: A method is provided for detecting an analyte indicative of a cancer or a metastatic disease condition, which utilizes the ability of the analyte to induce permeability in a barrier. The method includes providing a biosensor having a barrier which is substantially impermeable to an ion, a permeable membrane which is selective for the ion, and a detector capable of detecting the ion. The biosensor is contacted with a sample including at least one of the ion and the analyte, wherein the analyte causes at least a portion of the ion to pass through the barrier and the membrane. Passage of the ion through the barrier and membrane allows detection of the ion, providing indirect detection of the analyte. In one embodiment, the barrier is a cell monolayer, the membrane is selective for potassium, and the analyte is vascular endothelial cell growth factor.
    Type: Grant
    Filed: November 8, 2005
    Date of Patent: September 29, 2009
    Assignee: University of Kentucky Research Foundation
    Inventors: Kimberly W. Anderson, Kimberly M. L. May, Leonidas G. Bachas