Patents by Inventor Kimberly Martinod

Kimberly Martinod has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
    Patent number: 11819540
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: November 21, 2023
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
    Patent number: 11510970
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: November 29, 2022
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • Inhibition of JAK-STAT signaling inhibits formation of neutrophil extracellular traps (NETs)
    Patent number: 11426405
    Abstract: The methods described herein include methods for the treatment of subjects who have Clonal Hematopoiesis of Indeterminate Potential (CHIP) or a Philadelphia-negative myeloproliferative neoplasm (MPN), e.g., polycythaemia vera (PV) or essential thrombocythaemia (ET), using inhibitors of JAK-STAT signaling.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: August 30, 2022
    Assignees: The Brigham and Women's Hospital, Inc., Children's Medical Center Corporation
    Inventors: Rob Sellar, Benjamin Ebert, Ofir Wolach, Kimberly Martinod, Denisa Wagner
  • METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS
    Publication number: 20210023183
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Application
    Filed: October 2, 2020
    Publication date: January 28, 2021
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS
    Publication number: 20200206321
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Application
    Filed: February 27, 2020
    Publication date: July 2, 2020
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
    Patent number: 10617742
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries e.g., preventing transfusion-related acute lung injury (TRALI), by treating blood transfusion products with an anti-Neutrophil Extracellular Trap (NET) compound.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: April 14, 2020
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS
    Publication number: 20170196945
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neutrophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Application
    Filed: March 30, 2017
    Publication date: July 13, 2017
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • Methods for treating and preventing neutrophil-derived net toxicity and thrombosis
    Patent number: 9642822
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: May 9, 2017
    Assignee: Children's Medical Center Corporation
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas
  • METHODS FOR TREATING AND PREVENTING NEUTROPHIL-DERIVED NET TOXICITY AND THROMBOSIS
    Publication number: 20140199329
    Abstract: Embodiments of the technology described herein are based upon the discoveries that neturophil extracellular traps (NETs) provide a stimulus for thrombus formation and that NETs are present in stored blood products. Accordingly, some embodiments relate to methods of treating and preventing toxicity of NETs and thrombosis caused by NETs. Additional embodiments are directed towards methods of treating stored blood products to prevent transfusion-related injuries.
    Type: Application
    Filed: May 25, 2012
    Publication date: July 17, 2014
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Denisa D. Wagner, Tobias A. Fuchs, Simon De Meyer, Kimberly Martinod, Alexander Brill, Grace M. Thomas