Patents by Inventor Kimberly Palubin

Kimberly Palubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oct-1 as an oncoprotein and use of nucleic acid inhibitors of Oct-1 for cancer treatment
    Patent number: 7601696
    Abstract: Oct-1 is shown to be an oncoprotein because of its known role as an activator of the histone H2B gene and the importance of this gene during DNA synthesis. To determine the role of Oct-1 as an oncoprotein, the cell line 5637 (ATCC HTB9) was transfected with the vector pcDNA3 containing full length, antisense Oct-1 cDNA. This cell line is Rb-defective and has been shown to have increased Oct-1 binding activity as compared to Rb reconstituted clones. After transfection, Oct-1 antisense clones were grown and assayed for the loss of oncogenic characteristics as compared to control transformants.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: October 13, 2009
    Assignee: University of South Florida
    Inventors: George Blanck, Kimberly Palubin, Aaron Osborne