Patents by Inventor Kimberly S. Denis-Mize

Kimberly S. Denis-Mize has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microparticle-based transfection and activation of dendritic cells
    Patent number: 8097243
    Abstract: The present invention provides an effective method for the transfection of dendritic cells by non-viral methods. The present invention provides this benefit by incubating dendritic cells and a specified transfection agent. The transfection agent comprises a polynucleotide and microparticles, with the microparticles being comprised of biodegradable polymer and cationic detergent. The dendritic cells and transfection agent are incubated for a time sufficient to transfect the dendritic cells with the polynucleotide.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: January 17, 2012
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: John J. Donnelly, Kimberly S. Denis-Mize, Gary S. Ott
  • Microparticle-Based Transfection and Activation of Dendritic Cells
    Publication number: 20100196339
    Abstract: The present invention provides an effective method for the transfection of dendritic cells by non-viral methods. The present invention provides this benefit by incubating dendritic cells and a specified transfection agent. The transfection agent comprises a polynucleotide and microparticles, with the microparticles being comprised of biodegradable polymer and cationic detergent. The dendritic cells and transfection agent are incubated for a time sufficient to transfect the dendritic cells with the polynucleotide.
    Type: Application
    Filed: April 6, 2010
    Publication date: August 5, 2010
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS, INC.
    Inventors: John J. DONNELLY, Kimberly S. Denis-Mize, Gary S. Ott
  • Microparticle-based transfection and activation of dendritic cells
    Patent number: 7713739
    Abstract: The present invention provides an effective method for the transfection of dendritic cells by non-viral methods. The present invention provides this benefit by incubating dendritic cells and a specified transfection agent. The transfection agent comprises a polynucleotide and microparticles, with the microparticles being comprised of biodegradable polymer and cationic detergent. The dendritic cells and transfection agent are incubated for a time sufficient to transfect the dendritic cells with the polynucleotide.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: May 11, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: John J. Donnelly, Kimberly S. Denis-Mize, Gary S. Ott