Patents by Inventor Kimikazu Sugiyama

Kimikazu Sugiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10512915
    Abstract: A nucleic acid amplifier comprises a holder 3 which is provided with a plurality of temperature control blocks 10 each designed to hold at least one reaction vessel 105 storing a reaction solution. The temperature of the reaction solution in each reaction vessel 105 is controlled individually by using temperature control devices 14 and 15 arranged in each of the temperature control blocks 10. The temperature that is set in each temperature control block 10 and the timing for temperature changes are controlled independently of the temperatures of other temperature control blocks 10. This configuration makes it possible to provide a nucleic acid amplifier and a nucleic acid inspection device (employing the nucleic acid amplifier) capable of processing multiple types of samples differing in the protocol in parallel (parallel processing) and starting a process for a different sample even when there is a process in execution.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: December 24, 2019
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Minoru Sano, Yoshiyuki Shoji, Masato Ishizawa, Kimikazu Sugiyama
  • Patent number: 9993822
    Abstract: When taking in outside air with a fan to control the temperature inside a covered portion where a specimen is installed, the internal temperature may change depending on an environment temperature to cause a difference in temperature control. The wind generated by the fan may blow against a reaction container depending on its loading position and it may influence the temperature control over individual specimens and lead to problems with temperature accuracy, temperature rise speed, and temperature drop speed. A reaction container avoiding these problems has a covered portion which performs temperature control on the reaction container and in which a cover and a fin cover have a heat insulating structure. A heat source is provided for controlling an internal temperature of an internal covered space. The internal temperature is kept constant and the influence of the environment temperature over the temperature control of the reaction container is minimized.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: June 12, 2018
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kimikazu Sugiyama, Minoru Sano, Yasunori Shoji, Yoshiyuki Shoji, Yuki Kikuchi, Manami Nammoku, Ryoji Inaba
  • Patent number: 9714455
    Abstract: A device for detecting nucleic acid amplification in a sample, comprising: a loading unit (thermoregulation unit) which is provided with a plurality of holes for loading reaction containers and capable of arbitrarily controlling a measurement unit for measuring samples in the containers that are loaded in the holes. The loading unit and the measurement unit, which are placed opposite to each other, can be operated independently from each other. In a transfer operation, the operation speeds of the thermoregulation unit and measurement unit are controlled so that the sum of these speeds amounts to an arbitrary constant value.
    Type: Grant
    Filed: July 4, 2011
    Date of Patent: July 25, 2017
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Kimikazu Sugiyama, Masato Ishizawa, Yoshiyuki Shoji, Minoru Sano
  • Publication number: 20160144366
    Abstract: When taking in outside air with a fan to control the temperature inside a covered portion where a specimen is installed, the internal temperature may change depending on an environment temperature to cause a difference in temperature control. The wind generated by the fan may blow against a reaction container depending on its loading position and it may influence the temperature control over individual specimens and lead to problems with temperature accuracy, temperature rise speed, and temperature drop speed A reaction container avoiding these problems has a covered portion which performs temperature control on the reaction container and in which a cover and a fin cover have a heat insulating structure. A heat source is provided for controlling an internal temperature of an internal covered space. The internal temperature is kept constant and the influence of the environment temperature over the temperature control of the reaction container is minimized.
    Type: Application
    Filed: June 18, 2014
    Publication date: May 26, 2016
    Inventors: Kimikazu SUGIYAMA, Minoru SANO, Yasunori SHOJI, Yoshiyuki SHOJI, Yuki KIKUCHI, Manami NAMMOKU, Ryoji INABA
  • Publication number: 20130130229
    Abstract: A device for detecting nucleic acid amplification in a sample, comprising: a loading unit (thermoregulation unit) which is provided with a plurality of holes for loading reaction containers and capable of arbitrarily controlling a measurement unit for measuring samples in the containers that are loaded in the holes. The loading unit and the measurement unit, which are placed opposite to each other, can be operated independently from each other. In a transfer operation, the operation speeds of the thermoregulation unit and measurement unit are controlled so that the sum of these speeds amounts to an arbitrary constant value.
    Type: Application
    Filed: July 4, 2011
    Publication date: May 23, 2013
    Applicant: Hitachi High-Technologies Corporation
    Inventors: Kimikazu Sugiyama, Masato Ishizawa, Yoshiyuki Shoji, Minoru Sano
  • Publication number: 20130078712
    Abstract: A nucleic acid amplifier comprises a holder 3 which is provided with a plurality of temperature control blocks 10 each designed to hold at least one reaction vessel 105 storing a reaction solution. The temperature of the reaction solution in each reaction vessel 105 is controlled individually by using temperature control devices 14 and 15 arranged in each of the temperature control blocks 10. The temperature that is set in each temperature control block 10 and the timing for temperature changes are controlled independently of the temperatures of other temperature control blocks 10. This configuration makes it possible to provide a nucleic acid amplifier and a nucleic acid inspection device (employing the nucleic acid amplifier) capable of processing multiple types of samples differing in the protocol in parallel (parallel processing) and starting a process for a different sample even when there is a process in execution.
    Type: Application
    Filed: April 28, 2011
    Publication date: March 28, 2013
    Applicant: Hitachi High-Technologies Corporation
    Inventors: Minoru Sano, Yoshiyuki Shoji, Masato Ishizawa, Kimikazu Sugiyama
  • Patent number: 4347787
    Abstract: A product name stamping device of the label printers in which an ink-soaked member is provided to the stamp holder and a light and small ink-soaking member which contacts the ink-soaked member of the holder is fitted to the stamp. This construction make the stamp small and compact. The compactness of the stamp makes easy the handling and storage of a large number of stamps and also spares material bringing about a reduction in cost. The device is so constructed that setting the stamp into the holder automatically supplies ink to the stamp.
    Type: Grant
    Filed: August 14, 1980
    Date of Patent: September 7, 1982
    Assignee: Tokyo Electric Co., Ltd.
    Inventors: Yukihiro Takada, Kimikazu Sugiyama, Mithuo Imai