Abstract: An objective of the present invention is to provide intestinal absorptive antitumor agents with an excellent intestinal absorptive effect by using injectable antitumor agents. In the intestinal absorptive pharmaceutical agents of the present invention, antitumor components that can be used only as injections are supported by hydroxyapatite particles.

Abstract: An objective of the present invention is to provide intestinal absorptive antitumor agents with an excellent intestinal absorptive effect by using injectable antitumor agents. In the intestinal absorptive pharmaceutical agents of the present invention, antitumor components that can be used only as injections are supported by hydroxyapatite particles.

Abstract: Due to the toxicity of antitumor agents, use of antitumor agents is limited, and thus, it is desirable to develop auxiliary agents or antitumor agents that have the effect of reducing toxicity while maintaining the antitumor effect of antitumor agents. The present invention provides antitumor agents mixed with particulate hydroxyapatite as an auxiliary agent.

Abstract: Antitumor agents with high antitumor effect have much side-effect, and its activity decreases when the toxicity decreases. Thus, satisfactory antitumor effects are not always obtained. Therefore, development of an antitumor agent having a high antitumor effect, with less side-effect and low toxicity is awaited. The present invention is to provide an antitumor agent of fine particles, wherein platinum chloride, chloroplatinic acids and hydroxyapatite are blend. Platinum chloride and chloroplatinic acids are platinum tetrachloride, tetrachloroplatinate, hexachloroplatinate, disodium platinum tetrachloride, disodium platinum hexachloride, dipotassium platinum tetrachloride, or dipotassium platinum hexachloride. The maximum particle diameter of hydroxyapatite is 1 ?m or less.

Abstract: Transdermal and transmucosal preparations are often insufficiently absorbed. Thus, there is a need for additives that can enhance the transdermal and/or transmucosal absorption of various drugs. The present invention provides compositions for enhancing transdermal and/or transmucosal absorption, comprising a hydroxyapatite and essential ingredients. The hydroxyapatite has a maximum particle size of 1 ?m or less, preferably 0.1 ?m or less, and the content of the hydroxyapatite relative to a drug to be formulated ranges from 0.1 to 1000 weight percent.

Abstract: A work transfer apparatus is equipped with a work feeder 23, a rotatable turn table 11 formed several work-storing pockets 11a at its outer periphery and a separation mechanism 24 provided between the work feeder 23 and the turn table 11. The separation mechanism 24 has a communicating passage 24a. A work detector (15a, 15b) is provided in the work-storing pocket 11a. A work stopper 14 is provided at the work feeder 23 on an upstream side of the work detector (15a, 15b), for separating a preceding work W1 and the succeeding work W2.

Abstract: A process for the synthesis of chemical industrial feedstock and high-octane fuel, wherein calcium phosphate which is controlled in the molar Ca/P ratio and/or one which contains an activating metal (M) at a molar (Ca+M)/P ratio of 1 to 2 is used as the catalyst and ethanol is used as the feedstock.

Abstract: A composition for use in dental tissues includes hydroxyapatite having a particle size in a range from about 0.05 .mu.m to about 1.0 .mu.m. The amount of the hydroxyapatite is preferably a minimum of 0.1 percent by weight.

Abstract: A semiconductor circuit means having an electrode of a conductive protein, cytochrome C and/or mitochondria, which is attached to an insulating film of phosphate, especially calcium phosphate, deposited on a substrate of a silicon monocrystal. A small and effective integrated circuit is obtained.

Abstract: A catalyst for contact conversion of lower aliphatic alcohols such as methanol to form petroleum type hydrocarbons comprises one or more metals and/or metal ions supported on a phosphate carrier. Preferred metals include transition metals such as Ti, Ni, Cu, Zn, Rh, Ag, Ir and alkali metals, alkaline earth metals, Al and Sn. The phosphate carrier is preferably aluminium phosphate, zirconyl phosphate, magnesium phosphate, barium phosphate, zinc phosphate or a calcium phosphate compound. The metal should amount to 0.1 to 30% by weight with respect to the phosphate carrier. This catalyst is used to contact convert lower aliphatic alcohols to produce the gasoline type hydrocarbons at a reaction temperature of 200.degree. to 600.degree. C. and a supply rate of 0.75 to 3.0 weight units of alcohol per weight unit of catalyst per hour.

Abstract: A semiconductor integrated circuit comprises a conductive protein electrode, such as cytochrome c, deposited on the surface of an apatite insulating layer such as hydroxyapatite, fluorinated apatite or chlorinated apatite. The apatite insulating layer is thin film coated onto a substrate such that it is substantially C-axis (002) oriented, which allows the integrated circuit to be of small size while minimizing undesired electron transfer between electrodes because the conductive protein electrode adopts the orientation of the apatite insulating film.

Abstract: An antibacterial ceramic contains an antibacterial material produced by loading an antibacterial metal such as silver on a calcium ceramic carrier and an inorganic material such as cordierite, and has a bulk density of 0.6-1.2 g/cm.sup.3. An antibacterial ceramic filter contains an antibacterial material produced by loading an antibacterial metal such as silver on a calcium ceramic carrier, an aggregate such as mullite, and a binder such as frit, and has a porosity of 20% or more. The light-weight antibacterial ceramic is suitably applicable to a roof garden or the like. The antibacterial ceramic filter can remove and extirpate various bacteria and suspensions.

Abstract: A medicine injection device capable of continuously administrating a medicine to the body of a patient over a long period of time while keeping the patient from being restrained during administration. The medicine injection device includes a medicine container and at least one medicine passage each arranged in at least one of a root and a crown, so that a medicine stored in the medicine container is administrated through the medicine passage to the body of a patient.

Abstract: A catalyst for the conversion of lower aliphatic alcohols such as methanol to form petroleum type hydrocarbons comprises one or more metals and/or metal ions supported on a phosphate carrier. Preferred metals include transition metals such as Ti, Ni, Cu, Zn, Rh, Ag, Ir and alkali metals, alkaline earth metals, Al and Sn. The phosphate carrier is preferably aluminium phosphate, zirconyl phosphate, magnesium phosphate, barium phosphate, zinc phosphate or a calcium phosphate compound. The metal should amount to 0.1 to 30% by weight with respect to the phosphate carrier. This catalyst is used to convert lower aliphatic alcohols to produce the gasoline type hydrocarbons at a reaction temperature of 200.degree. to 600.degree. C. and a supply rate of 0.75 to 3.0 weight units of alcohol per weight unit of catalyst per hour.

Abstract: A dentifrice (tooth paste) having an antibacterial effect to prevent production of carious tooth and generation of periodontal diseases such as alveolar blennorrhea. The dentifrice contains hydroxylapatite powder. The hydroxylapatite powder carries therein an antibacterial metal such as silver, copper and/or zinc. The antibacterial metal is adsorbed to and/or combined, under ion exchange, with the hydroxylapatite powder.

Abstract: A calcium tertiary phosphate is used as a carrier, and the carrier is caused to carry silver and zinc. The result is an antibacterial ceramic exhibiting an ultra high degree of whiteness and suppressed discoloration. This material may be heat fired at a temperature above 960.degree. C. to obtain a further improvement.

Abstract: Disclosed is an agent for preventing the adhesion of water borne organisms, in which a calcium phosphate-based compound is made to carry, by adsorption and/or ion exchange, preferably not more than 15% by weight of at least one metal or metal ion selected from the group consisting of silver, copper, zinc and nickel. Also disclosed is a paint in which 0.1%-30% by weight of this agent is mixed.

Abstract: Antimicrobial hydroxyapatite powders containing hydroxyapatite power and one or more organic antimicrobial agents selected from hinokitiol, protamine and sorbic acid.

Abstract: A calcium phosphate ceramic such as hydroxyapatite or calcium tertiary phosphate or calcium carbonate is used as a carrier, and the carrier is caused to carry silicon in addition to silver, or silicon and zinc in addition to silver. The result is an antibacterial ceramic exhibiting an ultra high degree of whiteness and suppressed discoloration. This ceramic material may be heat-fired at a temperature above 960.degree. C. to obtain a further improvement.

Abstract: An antibacterial contact lens material comprising a hydrogel lens material and an antibacterial ceramic containing at least one metal selected from the group consisting of Ag, Cu and Zn. The lens material contains from 0.001-10.0% by weight of the antibacterial ceramic and the ceramic from 0.0001 to 10.0% by weight of the metal based on the weight of the ceramic.