Patents by Inventor Kimio HIRANO

Kimio HIRANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9855257
    Abstract: There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the derivatives have a superior EP4 receptor antagonistic action and are useful as pharmaceuticals for the treatment of diseases associated with the EP4 receptor, for example, as anti-inflammatory and/or analgesic drugs for inflammatory diseases and diseases that involve various kinds of pains, and further as pharmaceuticals for the treatment of immune diseases that result from inflammations as evoked by tissue destruction due to the activation of Th1 cells and/or Th17 cells:
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: January 2, 2018
    Assignee: KAKEN PHARMACEUTICAL CO., LTD.
    Inventors: Satoru Ikegami, Atsushi Watanabe, Kimio Hirano, Tadashi Ohyama
  • Publication number: 20170128431
    Abstract: There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the derivatives have a superior EP4 receptor antagonistic action and are useful as pharmaceuticals for the treatment of diseases associated with the EP4 receptor, for example, as anti-inflammatory and/or analgesic drugs for inflammatory diseases and diseases that involve various kinds of pains, and further as pharmaceuticals for the treatment of immune diseases that result from inflammations as evoked by tissue destruction due to the activation of Th1 cells and/or Th17 cells:
    Type: Application
    Filed: January 24, 2017
    Publication date: May 11, 2017
    Applicant: KAKEN PHARMACEUTICAL CO., LTD.
    Inventors: Satoru IKEGAMI, Atsushi WATANABE, Kimio HIRANO, Tadashi OHYAMA
  • Patent number: 9593081
    Abstract: There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the derivatives have a superior EP4 receptor antagonistic action and are useful as pharmaceuticals for the treatment of diseases associated with the EP4 receptor, for example, as anti-inflammatory and/or analgesic drugs for inflammatory diseases and diseases that involve various kinds of pains, and further as pharmaceuticals for the treatment of immune diseases that result from inflammations as evoked by tissue destruction due to the activation of Th1 cells and/or Th17 cells:
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: March 14, 2017
    Assignee: KAKEN PHARMACEUTICAL CO., LTD.
    Inventors: Satoru Ikegami, Atsushi Watanabe, Kimio Hirano, Tadashi Ohyama
  • Publication number: 20160130232
    Abstract: There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or phamaceutically acceptable salts thereof; the derivatives have a superior EP4 receptor antagonistic action and are useful as pharmaceuticals for the treatment of diseases associated with the EP4 receptor, for example, as anti-inflammatory and/or analgesic drugs for inflammatory diseases and diseases that involve various kinds of pains, and further as pharmaceuticals for the treatment of immune diseases that result from inflammations as evoked by tissue destruction due to the activation of Th1 cells and/or Th17 cells:
    Type: Application
    Filed: June 12, 2014
    Publication date: May 12, 2016
    Applicant: KAKEN PHARMACEUTICAL CO., LTD.
    Inventors: Satoru IKEGAMI, Atsushi WATANABE, Kimio HIRANO, Tadashi OHYAMA