Abstract: A sheet feeding device includes a supply tray with a support surface supporting stacked sheets, and a feeding roller that feeds an uppermost sheet in a feeding direction orthogonal to a widthwise direction of the sheets. A first guide surface downstream of the support surface guides the fed sheet. A second guide surface downstream and alongside the first guide surface in the widthwise direction guides a sheet portion to lift it away from the first guide surface. A friction member includes a first portion on the support surface facing the feeding roller from below to apply friction to stacked sheets, and a second portion on the first guide surface alongside the second guide surface, with a downstream region positioned below the second guide surface to apply friction to guided sheets. This configuration suppresses double feeding even when sheets are deformed.

Abstract: A sheet feeding device includes a supply tray having a support surface, a feed roller configured to feed a sheet in a feeding direction orthogonal to a widthwise direction of the support surface, and a shutter swingable between a regulation position and a retracted position. When in the regulation position, the shutter regulates a leading edge of a sheet inserted along the support surface, and when in the retracted position, the shutter does not interfere with advancement of the sheet. The shutter includes a plurality of first regulation surfaces arranged in an up-down direction and facing upstream in the feeding direction, and at least one second regulation surface located between adjacent first regulation surfaces and facing downward. A lower first regulation surface is positioned downstream of an upper first regulation surface, and the second regulation surface connects ends of the adjacent first regulation surfaces.

Abstract: An image forming apparatus includes a photosensitive drum and a fuser. The fuser includes an upper frame. The upper frame includes an upper first rib downstream of a heating rotating member in a sheet conveying direction, an upper second rib adjacent to the upper first rib in a width direction perpendicular to the sheet conveying direction, and first and second conveying rollers. The upper first rib includes a first guide surface, and a separation surface. The upper second rib includes a second guide surface. The second guide surface is located downstream of the first guide surface in the sheet conveying direction. A distance between a nip point between the first and second conveying rollers and the second guide surface in a direction perpendicular to the sheet conveying direction and the width direction is smaller than a distance between the nip point and the separation surface.

Abstract: An image forming apparatus includes a photosensitive drum and a fuser. The fuser includes an upper frame. The upper frame includes an upper first rib downstream of a heating rotating member in a sheet conveying direction, an upper second rib adjacent to the upper first rib in a width direction perpendicular to the sheet conveying direction, and first and second conveying rollers. The upper first rib includes a first guide surface, and a separation surface. The upper second rib includes a second guide surface. The second guide surface is located downstream of the first guide surface in the sheet conveying direction. A distance between a nip point between the first and second conveying rollers and the second guide surface in a direction perpendicular to the sheet conveying direction and the width direction is smaller than a distance between the nip point and the separation surface.

Abstract: Methods of treating ocular neovascularization, e.g., associated with wet age-related macular degeneration (AMD), using activators of AMP-activated protein kinase (AMPK) and/or of Phosphatase and tensin homolog deleted on chromosome 10 (PTEN).

Abstract: Methods of treating ocular neovascularization, e.g., associated with wet agerelated macular degeneration (AMD), using activators of AMP-activated protein kinase (AMPK) and/or of Phosphatase and tensin homolog deleted on chromosome 10 (PTEN).

Abstract: Methods of treating ocular neovascularization, e.g., associated with wet agerelated macular degeneration (AMD), using activators of AMP-activated protein kinase (AMPK) and/or of Phosphatase and tensin homolog deleted on chromosome 10 (PTEN).

Abstract: A pouring member includes an unsealing cap and at least two rotation prevention sections extending vertically and downwardly from an end surface of an open end side of the unsealing cap and is arranged such that the at least two rotation prevention sections are apart from one another by an angle which is larger than a rotation angle required for twisting off the sealing part, and symmetrically with respect to the central axis of the unsealing cap. A recess is formed such that the recess opens to a front end side of the rotation prevention section, and an engagement projection engages the recess in a direction substantially parallel with a direction in which the rotation prevention sections are extended vertically and downwardly, and is formed at a specific position of the flange part of the pouring member.

Abstract: A composite spout obtained by injection forming a spout body in a state where a sleeve having a functional resin layer disposed as an intermediate layer is fitted as a core onto the core member of an injection-forming metal mold such that the inner peripheral surface only of the sleeve is substantially exposed on the inner peripheral surface of the spout body. A tilted surface is formed on the inner peripheral surface at one end of the spout body in at least a portion thereof in the circumferential direction, the tilted surface being tilted outward in the radial direction from a position in agreement with the inner peripheral edge at the one end of the sleeve or from the inside thereof in the radial direction facing the one end of the spout body.

Abstract: A method and a device for feeding a molten resin capable of accurately feeding the molten resin without the delay of feed timing by preventing the molten resin from adhering to route members before it seats on a mold to increase the positioning accuracy of the molten metal in the mold, and a method of manufacturing a molded part by using the fed molten resin. Vibration is provided to the route members such as molten resin guide pins (10, 40, 50), throat members (62, 70, 85), and female mold positioned in a route in which the molten resin (25) passes before it seats on the female mold (7, 63) by a vibration imparting device (27) or a gas layer film is formed on the surfaces thereof. Thus, the molten resin can be fed while preventing it from adhering to the route members.

Abstract: A method and a device for feeding a molten resin capable of accurately feeding the molten resin without the delay of feed timing by preventing the molten resin from adhering to route members before it seats on a mold to increase the positioning accuracy of the molten metal in the mold, and a method of manufacturing a molded part by using the fed molten resin. Vibration is provided to the route members such as molten resin guide pins (10, 40, 50), throat members (62, 70, 85), and female mold positioned in a route in which the molten resin (25) passes before it seats on the female mold (7, 63) by a vibration imparting device (27) or a gas layer film is formed on the surfaces thereof. Thus, the molten resin can be fed while preventing it from adhering to the route members.

Abstract: Two or more rotation prevention sections 3d are extended vertically and downwardly and symmetrically with respect to the central axis from the end surface on the open end side of an unsealing cap 3, and, at substantially the center of the width direction of each rotation prevention section 3d, a recess 3e is formed such that it opens to the front end side of the rotation prevention section, and an engagement projection 2b which is engaged with said recess 3e in a direction almost parallel with the direction in which said rotation prevention sections 3d are extended vertically and downwardly is formed at a specific position of a flange part 2c provided in a boundary between a base part 23 and a pouring cylindrical part 22 of said pouring member main body 2, whereby unnecessary rotation of the unsealing cap 3 can be prevented and a user can easily judge whether unsealing has been completed.

Abstract: A method and a device for feeding a molten resin capable of accurately feeding the molten resin without the delay of feed timing by preventing the molten resin from adhering to route members before it seats on a mold to increase the positioning accuracy of the molten metal in the mold, and a method of manufacturing a molded part by using the fed molten resin. Vibration is provided to the route members such as molten resin guide pins (10, 40, 50), throat members (62, 70, 85), and female mold positioned in a route in which the molten resin (25) passes before it seats on the female mold (7, 63) by a vibration imparting device (27) or a gas layer film is formed on the surfaces thereof. Thus, the molten resin can be fed while preventing it from adhering to the route members.

Abstract: A method and a device for feeding a molten resin capable of accurately feeding the molten resin without the delay of feed timing by preventing the molten resin from adhering to route members before it seats on a mold to increase the positioning accuracy of the molten metal in the mold, and a method of manufacturing a molded part by using the fed molten resin. Vibration is provided to the route members such as molten resin guide pins (10, 40, 50), throat members (62, 70, 85), and female mold positioned in a route in which the molten resin (25) passes before it seats on the female mold (7, 63) by a vibration imparting device (27) or a gas layer film is formed on the surfaces thereof. Thus, the molten resin can be fed while preventing it from adhering to the route members.

Abstract: A composite spout which does not permit a sleeve fitted onto the core to be deviated during the injection forming and does not permit end surfaces of the sleeve to be exposed in the spout body. A spout body is injection-formed in a state where a sleeve having a functional resin layer disposed as an intermediate layer is fitted as a core onto the core member of an injection-forming metal mold such that the inner peripheral surface only of the sleeve is substantially exposed on the inner peripheral surface of the spout body. A tilted surface is formed on the inner peripheral surface at one end of the spout body in at least a portion thereof in the circumferential direction, the tilted surface being tilted outward in the radial direction from a position in agreement with the inner peripheral edge at the one end of the sleeve or from the inside thereof in the radial direction facing the one end of the spout body.

Abstract: The invention provides a spout for a pouch, which can be reliably heat-sealed with a plastic pouch body to provide an excellent gas-shielding capability for preventing gas permeation through the spout itself, and can be simply manufactured at a low cost without requiring complicated processes and special materials. In a spout for a pouch, comprising a tubular mouth part having a cap fitting portion and a seal part connected to a lower end portion of the mouth part for sealing with the pouch, the invention is featured in that a horizontal cross-sectional shape of the seal part is different in a height direction between an upper end portion and a lower end portion thereof, and an outer peripheral length of the horizontal cross-sectional shape is substantially equal at any position between the upper end portion and the lower end portion of the seal part.

Abstract: A pouring mouth member for a container includes an intermediate resin layer having barrier property and a fold-back portion is formed on at least one end portion of the intermediate resin layer having barrier property. Further, due to an inner layer resin and/or an outer layer resin provided to an outer periphery of this fold-back portion, the exposure of the resin having barrier property can be surely prevented and, at the same time, a cut edge of the intermediate resin layer having barrier property is effectively sealed between the inner and outer layer resins since the cut edge is also in a fold-back state.

Abstract: A pouring mouth member for a container includes an intermediate resin layer having barrier property and a fold-back portion is formed on at least one end portion of the intermediate resin layer having barrier property. Further, due to an inner layer resin and/or an outer layer resin provided to an outer periphery of this fold-back portion, the exposure of the resin having barrier property can be surely prevented and, at the same time, a cut edge of the intermediate resin layer having barrier property is effectively sealed between the inner and outer layer resins since the cut edge is also in a fold-back state.

Abstract: A container obtained by biaxially stretch-blow-molding a resin. Except the mouth-and-neck portion, vicinities thereof and the center of the bottom portion, the container as a whole is reduced in thickness under a highly drawing condition without accompanied by whitening, and a portion constituting the bottom valley portions has an yielding load of not smaller than 25 kg/cm at 70.degree. C. The container exhibits excellent heat resistance, pressure resistance, shock resistance as well as self-standing ability.

Abstract: A container is obtained by biaxially stretch-blow-molding a resin. Except the mouth-and-neck portion, vicinities thereof and the center of the bottom portion, the container as a whole is reduced in thickness under a highly drawing condition without being accompanied by whitening, and a portion constituting the bottom valley portions has an yielding load of not smaller than 25 kg/cm at 70.degree. C. The container exhibits excellent heat resistance, pressure resistance, shock resistance as well as self-standing ability.