Patents by Inventor Kimonobu Sugaya

Kimonobu Sugaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of promoting apoptosis of glioblastoma tumor cells
    Patent number: 8518698
    Abstract: The invention provides a method of promoting apoptosis of human glioblastoma multiforme (GBM) tumor cells. The method comprises isolating GBM tumor cells from a human brain biopsy specimen, isolating human neural stem cells (HNSCs) from the biopsy specimen, transforming the isolated HNSCs with an operative PEX gene, and exposing GBM tumor cells to the transformed HNSCs to thereby promote apoptosis of the tumor cells mediated by the expressed PEX gene.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: August 27, 2013
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Kimonobu Sugaya, Stacey Mont, Angel Alvarez
  • Methods for modifying stem cell characteristics
    Patent number: 8105832
    Abstract: The invention provides a method of up-regulating genes in cultured human bone marrow mesenchymal stem cells, the method comprising culturing the stem cells in a nutrient medium together with cells from a limb of a limb-regenerating animal. In the method, the limb-regenerating animal is preferably a species of the family Polychrotidae. Another method of the invention provides for up-regulating genes maintaining pluripotency and proliferation in cultured human bone marrow mesenchymal stem cells by culturing the stem cells in a nutrient medium together with mouse embryonic stem cells.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: January 31, 2012
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Kimonobu Sugaya, Angel Alvarez