Abstract: The present subject matter is directed to a luminogen exhibiting aggregation induced emission, wherein T1, T2, and T3 comprise one or more polyynes as a conjugated bridge. The present subject matter is also directed to an AIEgen comprising a hydrophilic pyridium group as a strong electron-withdrawing group; a piperazine group as an electron-donating group; and a ?-Cyanostilbene; wherein the AIEgen exhibits aggregation induced emission. The present subject matter is directed to a method of synthesizing an AIEgen and is further directed to a method of labeling comprising incubating a subject having cells with a conjugate formed by conjugating an AIEgen with an antibody; and selectively labeling desired cells by turn-on imaging, wherein labeling occurs when the desired cells are selectively stained by fluorescent emission of the AIEgen upon degradation of the antibody after cellular internalization of the conjugate through endocytosis.

Abstract: A decorative lighting system including a sensor device; a wiring harness comprising an insulated conductor and a plurality of lighting elements; a controller in communication with the wiring harness and the sensor device, the controller comprising a processor, a memory, and a wireless communication module; and wherein the controller is configured to control the plurality of lighting elements based at least in part on information received from the sensor device.

Abstract: A method of facilitating controlled particle deposition from a droplet dispenser involves receiving at least one pre-dispensed image of a dispensing portion of the droplet dispenser, the dispensing portion including fluid to be dispensed in a subject droplet to a subject target region, receiving at least one post-dispensed image of the dispensing portion of the droplet dispenser after the subject droplet has been dispensed, comparing the at least one pre-dispensed image and the at least one post-dispensed image to determine a subject droplet particle count representing a count of particles included in the subject droplet, and producing signals for associating a representation of the subject droplet particle count with the subject target region. Other methods, apparatuses, systems, and non-transitory computer readable media are disclosed.

Abstract: The present subject matter is directed to a luminogen exhibiting aggregation induced emission, wherein T1, T2, and T3 comprise one or more polyynes as a conjugated bridge. The present subject matter is also directed to an AIEgen comprising a hydrophilic pyridium group as a strong electron-withdrawing group; a piperazine group as an electron-donating group; and a ?-Cyanostilbene; wherein the AIEgen exhibits aggregation induced emission. The present subject matter is directed to a method of synthesizing an AIEgen and is further directed to a method of labeling comprising incubating a subject having cells with a conjugate formed by conjugating an AIEgen with an antibody; and selectively labeling desired cells by turn-on imaging, wherein labeling occurs when the desired cells are selectively stained by fluorescent emission of the AIEgen upon degradation of the antibody after cellular internalization of the conjugate through endocytosis.

Abstract: An in-line switch assembly comprising a housing and two ports at different parts of the housing for insertion of an end of a power cord into the housing. The housing has first and second housing parts. A connection mechanism is provided in each of the ports, adapted to receive an end of a power cord, and is operable to cause piercing of a piercing part through a sheath of a power cord and then electrical contact with a conductive core of the power cord. The housing is configured to undergo from a first state in which the first and second housing parts are partially attached together, thereby allowing insertion of an end of a power cord through each of the ports to the respective connection mechanism, to a second state in which the first and second housing parts are fully attached together, with an inserted end of a said power cord being acted upon by the connection mechanism.

Abstract: An in-line switch assembly comprising a housing and two ports at different parts of the housing for insertion of an end of a power cord into the housing. The housing has first and second housing parts. A connection mechanism is provided in each of the ports, adapted to receive an end of a power cord, and is operable to cause piercing of a piercing part through a sheath of a power cord and then electrical contact with a conductive core of the power cord. The housing is configured to undergo from a first state in which the first and second housing parts are partially attached together, thereby allowing insertion of an end of a power cord through each of the ports to the respective connection mechanism, to a second state in which the first and second housing parts are fully attached together, with an inserted end of a said power cord being acted upon by the connection mechanism.

Abstract: The present subject matter relates to ATE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.

Abstract: The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.

Abstract: The present subject matter relates to ATE luminogens for visualization and treatment of cancer, particularly AIE luminogenic probes for cancer cell visualization and discrimination, lysosome-targeting AIEgens for imaging and autophagy visualization, highly fluorescent AIE-active theranostic agents for monitoring drug distribution and having anti-tumor activity to specific cancer cells, probes comprising AIE luminogens for cancer cell imaging and staining, AIE luminogens having clusteroluminogenic features and applications thereof, and methods of preparing thereof.

Abstract: Method and systems for processing at least one three-dimensional (3D) graphic object include: identifying a change of 3D graphic objects, creating a message, assigning a unique identifier; and forwarding the message and the unique identifier to a scene engine. The change is made by an authoring tool. The message is embedded with change information corresponding to the change. The scene engine functions can be performed by the same or a different computing device as the computing device performing the authoring tool.

Abstract: Method and systems for processing at least one three-dimensional (3D) graphic object include: identifying a change of 3D graphic objects, creating a message, assigning a unique identifier; and forwarding the message and the unique identifier to a scene engine. The change is made by an authoring tool. The message is embedded with change information corresponding to the change. The scene engine functions can be performed by the same or a different computing device as the computing device performing the authoring tool.

Abstract: Provided herein are fluorescent bioprobes comprising fluorogens that exhibit aggregation-induced emission (AIE) labeled on biomolecules. The present subject matter relates to a fluorescent bioprobe comprising one or more fluorogen labeled on chitosan. The present subject matter is also directed to methods of preparing the fluorescent bioprobes, methods of labeling and detecting DNA and/or proteins with the fluorescent bioprobe, and methods of cell imaging including live cell tracking.

Abstract: Method and systems for processing at least one three-dimensional (3D) graphic object include: identifying a change of 3D graphic objects, creating a message, assigning a unique identifier; and forwarding the message and the unique identifier to a scene engine. The change is made by an authoring tool. The message is embedded with change information corresponding to the change. The scene engine functions can be performed by the same or a different computing device as the computing device performing the authoring tool.

Abstract: The present invention is drawn toward luminogens and chemical compositions comprising a target recognition motif, a hydrophilic moiety, a linking moiety, and at least one luminogen. Additionally presented are methods of: assessing the conversion of a prodrug into its active form, assessing the therapeutic efficacy of a prodrug, detecting glutathione in a biological sample, detecting alkaline phosphatase in a sample, and conducting fluorescence imaging or magnetic resonance imaging with the use of luminogen-containing compositions.

Abstract: The development of fluorescent bioprobes comprising organic fluorescent compounds that exhibit aggregation induced emission (AIE) properties, methods of producing the same, and their practical applications for in vitro and in vivo bioimaging.

Abstract: Method and systems for processing at least one three-dimensional (3D) graphic object include: identifying a change of 3D graphic objects, creating a message, assigning a unique identifier; and forwarding the message and the unique identifier to a scene engine. The change is made by an authoring tool. The message is embedded with change information corresponding to the change. The scene engine functions can be performed by the same or a different computing device as the computing device performing the authoring tool.

Abstract: The presently described subject matter is directed to a water-soluble conjugated polyene compound and the derivatives thereof that exhibit aggregation induced emission, as well as any water dispersible, fluorescent, polymeric microparticles, nanoparticles, and/or pharmaceutical composition comprising the water-soluble conjugated polyene compound and/or the derivatives thereof. Also provided are methods of making and using the compound, derivatives and particles of the presently described subject matter. The presently described water-soluble conjugated polyene compound are useful as bioprobes for the detection of biomacromolecules, in the manufacture of sensors, in monitoring and retarding formation of amyloid protein fibril in vitro and in vivo, and in developing anti-cancer drugs.

Abstract: The invention provides a cord switch for controlling a LED lamp, comprising a casing, a push button switch that consists of a push button and a conductive slice arranged in the casing, and connection terminals and housings for the connection terminals. Each connection terminal has a plug or a pin at its front end and a rivet portion at its rear end. The housing receives the connection terminals, forming a connector which is then inserted into the casing, with a part of the plug or the pin in close contact with the conductive slice. For this cord switch, the wire connection comprises the steps of riveting wires in the rivet portion at the rear end of the connection terminals, inserting the connection terminals into the housing to form a connector, and inserting the connector into the casing, without need to disassemble and reassemble the casing, or fasten the bolts.

Abstract: The presently described subject matter is directed to a water-soluble conjugated polyene compound and the derivatives thereof that exhibit aggregation induced emission, as well as any water dispersible, fluorescent, polymeric microparticles, nanoparticles, and/or pharmaceutical composition comprising the water-soluble conjugated polyene compound and/or the derivatives thereof. Also provided are methods of making and using the compound, derivatives and particles of the presently described subject matter. The presently described water-soluble conjugated polyene compound are useful as bioprobes for the detection of biomacromolecules, in the manufacture of sensors, in monitoring and retarding formation of amyloid protein fibril in vitro and in vivo, and in developing anti-cancer drugs.