Abstract: The present invention discloses the use of winter melon wax as a preservative and an antimicrobial agent. In addition, the present invention also discloses a kind of powder of artificial winter melon wax, which is obtained by spray drying the solution of following components with ratios by weight: 30-55% triterpenenol, 10%-20% triterpenenol acetate and 35-60% wax. Experiments proved that the natural winter melon wax and the artificial Winter melon wax powder prepared by the invention had antiseptic and anti-microbial effects, could significantly improve the shelf life of fruits, and had a promoting effect on wound healing.

Abstract: The present invention provides extracts of Lycium barbarum useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method for treating a disease associated with angiogenesis or neovascularization in a subject, comprising administering an effective amount of an extract of Lycium barbarum to the subject.

Abstract: The present invention provides methods of reducing angiogenesis in an individual. The methods generally involve administering to the individual an effective amount of a tanshinone compound. The methods are useful to treat conditions associated with or resulting from angiogenesis, particularly pathological angiogenesis. The invention further provides methods of treating a condition associated with or resulting from angiogenesis.

Abstract: The present invention provides extracts of Trapa natans L. useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Trapa natans L. to the subject.

Abstract: The present invention provides extracts of Lycium barbarum useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastasis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Lycium barbarum to the subject.

Abstract: The present invention provides extracts of Stephaniae sinica Diels useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Stephaniae sinica Diels to the subject.

Abstract: The present invention provides extracts of Trapa natans L. useful for inhibiting, interfering and/or controlling pathological angiogenesis or neovascularization of tissues. The invention also provides a method to inhibit metastatis of cancer of colon, lung, liver, kidney, breast and/or cervix in a subject, comprising administering an effective amount of an extract of Trapa natans L. to the subject.

Abstract: This invention provides processes for extracting pharmaceutically active fractions from Hedyotis Diffusae. This invention provides a method for inhibiting the growth of endothelial cells by delivering to the cells a growth inhibitory amount of a fraction. This invention also provides a method of inhibiting vascularization in a tissue by delivering to the tissue an anti-vascularization amount of a fraction. Methods of treating various diseases, including cancer, are also provided herein.

Abstract: This invention also provides a method to inhibit neovascularization in tissue by delivering to the cell or tissue an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Also provided herein is a method for treating a disease associated with hyproliferation of endothelial cells and/or neovascularization by administering to a subject an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Kits to treat patients are provided as well.

Abstract: This invention provides processes to obtain pharmaceutically active fractions from the fungus Ganoderma Lucidum. In one aspect, the process requires extracting from a homogenate of Ganoderma Lucidum a fraction isolated by column chromatography that has an optical absorbance between about 200 nm to about 280 nm. The compound and extracts are useful to inhibit the growth of endothelial cells and to inhibit vascularization in a tissue. Methods of treating various diseases, including cancer and arthritis, are also provided herein.

Abstract: This invention provides processes for isolating pharmaceutically active extracts, fractions and compounds from the mushroom Tricholoma Conglobatum. In one aspect, a homogenate of Tricholoma Conglobatum is extracted from a fraction isolated by column chromatography. It has an optical absorbance between about 210 nm and about 350 nm and is not heat stable. The active compound, having a molecular weight from about 18 to about 20 kD on SDS-PAGE gel, in the extract is further provided by this invention. A second active fraction isolated from the homogenate of Tricholoma Conglobatum can be further processed to separate into two additionally active compounds each of which has characteristics consistent with that of a protein. The fractions, compounds and extracts are useful to inhibit the growth of endothelial cells and to inhibit vascularization in a tissue. Methods of treating various diseases, including cancer, are also provided herein.

Abstract: This invention also provides a method to inhibit neovascularization in tissue by delivering to the cell or tissue an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Also provided herein is a method for treating a disease associated with hyproliferation of endothelial cells and/or neovascularization by administering to a subject an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative or prodrug thereof. Kits to treat patients are provided as well.

Abstract: This invention provides processes for extracting pharmaceutically active fractions from Hedyotis Diffusae. This invention provides a method for inhibiting the growth of endothelial cells by delivering to the cells a growth inhibitory amount of a fraction. This invention also provides a method of inhibiting vascularization in a tissue by delivering to the tissue an anti-vascularization amount of a fraction. Methods of treating various diseases, including cancer, are also provided herein.

Abstract: This invention provides processes for isolating pharmaceutically active fractions from the mushroom Scutellariae barbatae designated herein as ESBa, ESBb and ASB03. This invention provides a method for inhibiting the growth of endothelial cells by delivering to the cells a growth inhibitory amount of a fraction of this invention. This invention also provides a method of inhibiting vascularization in a tissue by delivering to the tissue an anti-vascularization amount of a fraction of this invention. Methods of treating various diseases, including cancer, are also provided herein.