Patents by Inventor King L. Chow

King L. Chow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated skeletal actin promoter
    Patent number: 5374544
    Abstract: A mutated skeletal actin promoter which differs from the naturally occurring DNA sequence by nucleotide substitution has been found to increase gene expression. The mutation sites are specific to the cis-acting regions of the gene. Double mutations created a strong promoter. Transformed myogenic cells had ten times the transcriptional activity over the wild type. The mutated skeletal actin promoter can be used to overly express polypeptides, particularly in myogenic cells.
    Type: Grant
    Filed: January 15, 1992
    Date of Patent: December 20, 1994
    Assignee: Baylor College of Medicine
    Inventors: Robert J. Schwartz, King L. Chow