Patents by Inventor Kingsley IBHAZEHIEBO

Kingsley IBHAZEHIEBO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220098257
    Abstract: Provided are methods of treating epilepsy. The methods include administering to an individual having epilepsy a therapeutically effective amount of a phosphodiesterase 4 (PDE4) inhibitor. Also provided are methods of identifying an anti-epileptic agent. Such methods include contacting a PDE4 polypeptide with a candidate agent in a PDE4 activity assay, where inhibition of activity of the PDE4 polypeptide by the candidate agent identifies the candidate agent as an anti-epileptic agent.
    Type: Application
    Filed: January 23, 2020
    Publication date: March 31, 2022
    Inventors: Deborah Kurrasch, Kingsley Ibhazehiebo
  • Patent number: 11013219
    Abstract: The present application provides a novel drug screening platform designed to identify drugs that favorably modulate cellular bioenergetics in the human brain of a zebrafish which has been modified by altering a teleost gene that corresponds to a human gene associated with a brain dysfunction disorder (such as epilepsy). The drug screening platform are also useful for determining a mutation in a human gene associated with a brain dysfunction disorder that is associated with a human individual responsive to the treatment of a compound. Also provided are modified teleosts useful for the methods described herein.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: May 25, 2021
    Assignee: Path Therapeutics, Inc.
    Inventors: Deborah M. Kurrasch, Jong Rho, Kingsley Ibhazehiebo
  • Publication number: 20160338327
    Abstract: The present application provides a novel drug screening platform designed to identify drugs that favorably modulate cellular bioenergetics in the human brain of a zebrafish which has been modified by altering a teleost gene that corresponds to a human gene associated with a brain dysfunction disorder (such as epilepsy). The drug screening platform are also useful for determining a mutation in a human gene associated with a brain dysfunction disorder that is associated with a human individual responsive to the treatment of a compound. Also provided are modified teleosts useful for the methods described herein.
    Type: Application
    Filed: January 16, 2015
    Publication date: November 24, 2016
    Applicant: Path Therapeutics, Inc.
    Inventors: Deborah M. KURRASCH, Jong RHO, Kingsley IBHAZEHIEBO