Patents by Inventor Kinsey Maundrell

Kinsey Maundrell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies specific for MMP9
    Patent number: 10364296
    Abstract: The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.
    Type: Grant
    Filed: August 13, 2015
    Date of Patent: July 30, 2019
    Assignees: CALYPSO BIOTECH SA, MERCK PATENT GMBH
    Inventors: Yolande Chvatchko Missotten, Laurence Goffin, Olivier Leger, Steven M. Dunn, Christine Power, Kinsey Maundrell
  • ANTIBODIES SPECIFIC FOR MMP9
    Publication number: 20170233495
    Abstract: The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers. In particular, the MMP9 binding proteins according to the invention are useful in diagnosis of MMP9-related disorders.
    Type: Application
    Filed: August 13, 2015
    Publication date: August 17, 2017
    Inventors: YOLANDE CHVATCHKO MISSOTTEN, LAURENCE GOFFIN, OLIVIER LEGER, STEVEN M. DUNN, CHRISTINE POWER, KINSEY MAUNDRELL
  • Variation of Recombinant Expression Titres By Optimising Bacterial Ribosome Binding Sites
    Publication number: 20110104752
    Abstract: The present invention provides a method for optimising the ribosome binding site of a promoter for the expression of a gene encoding a polypeptide of interest, placed under the control of said promoter. The invention also relates to a vector containing such optimised promoters, a prokaryotic host cell transformed by said vector, as well as a method for producing a recombinant protein of interest.
    Type: Application
    Filed: March 13, 2009
    Publication date: May 5, 2011
    Applicant: Merck Serono S.A.
    Inventors: Laurent Chevalet, Kinsey Maundrell
  • USE OF PRION CONVERSION MODULATING AGENTS
    Publication number: 20090317380
    Abstract: The use of Apolipoprotein B, Apoliporpotein E, fragments and mimetics thereof is provided for diagnostic, detection, prognostic and therapeutic applications in prion diseases. More specifically, the invention provides the use of Apolipoprotein B or fragments thereof for modulating or identifying modulators of the prion protein replication which are implicated in the pathogenesis of transmissible spongiform encephalopathies and other prion diseases.
    Type: Application
    Filed: August 27, 2009
    Publication date: December 24, 2009
    Applicant: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
    Inventors: Claudio SOTO-JARA, Kinsey Maundrell
  • Use of prion conversion modulating agents
    Patent number: 7598046
    Abstract: The use of Apolipoprotein B, Apolipoprotein E, fragments and mimetics thereof is provided for diagnostic, detection, prognostic and therapeutic applications In prion diseases. More specifically, the invention provides the use of Apolipoprotein B or fragments thereof for modulating or identifying modulators of the prion protein replication which are implicated in the pathogenesis of transmissible spongiform encephalopathics and other prion diseases.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: October 6, 2009
    Assignee: Laboratories Serono SA
    Inventors: Claudio Soto-Jara, Kinsey Maundrell
  • Erythropoietin Polypeptides and Uses Thereof
    Publication number: 20080260746
    Abstract: The present invention relates to EPO polypeptides and their uses, particularly for therapeutic or prophylactic treatment in human subjects. The invention also relates to nucleic acids encoding said polypeptides, vectors comprising such nucleic acids and recombinant cells containing the same. The invention further discloses methods of producing such polypeptides, as well as methods and tools for detecting or dosing these polypeptides in any sample.
    Type: Application
    Filed: November 23, 2006
    Publication date: October 23, 2008
    Applicant: Laboratoires Serono SA
    Inventors: Hadi Abderrahim, Gwenael Primas, Yolande Chvatchko, Kinsey Maundrell
  • Anti-Lipid Rafts Antibodies
    Publication number: 20080057057
    Abstract: The present invention relates to the discovery of antibodies able to modulate (prevent or favour) conversion of PrPc to PrPSc and to their antigens. Depending on the nature of the antibodies (antagonistic or agonistic), their respective antigens are either conversion factors or inhibitors of prion replication.
    Type: Application
    Filed: March 18, 2005
    Publication date: March 6, 2008
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventor: Kinsey Maundrell
  • Use of prion conversion modulating agents
    Publication number: 20070020682
    Abstract: The use of Apolipoprotein B, Apolipoprotein E, fragments and mimetics thereof is provided for diagnostic, detection, prognostic and therapeutic applications In prion diseases. More specifically, the invention provides the use of Apolipoprotein B or fragments thereof for modulating or identifying modulators of the prion protein replication which are implicated in the pathogenesis of transmissible spongiform encephalopathics and other prion diseases.
    Type: Application
    Filed: June 18, 2004
    Publication date: January 25, 2007
    Applicant: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
    Inventors: Claudio Soto-Jara, Kinsey Maundrell