Patents by Inventor Kiran Chandrashekhar Kulkarni

Kiran Chandrashekhar Kulkarni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS
    Publication number: 20210052556
    Abstract: Disclosed are compounds of the general formula (I), wherein R1-R3 are as defined herein, for use as MALT1 inhibitors in the treatment of autoimmune and inflammatory diseases or disorders. Methods of synthesizing the compounds are also disclosed. Also disclosed are pharmaceutical compositions containing a compound of the invention and a method of treating a patient for an autoimmune or an inflammatory disease or disorder, for example, a cancer, by administering a compound of the invention.
    Type: Application
    Filed: March 26, 2020
    Publication date: February 25, 2021
    Inventors: Gagan Kukreja, Nageswara Rao Irlapati, Arun Rangnath Jagdale, Gokul Keruji Deshmukh, Vinod Popatrao Vyavahare, Kiran Chandrashekhar Kulkarni, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS
    Publication number: 20190275012
    Abstract: Disclosed are compounds of the general formula (I), wherein R1-R3 are as defined herein, for use as MALT1 inhibitors in the treatment of autoimmune and inflammatory diseases or disorders. Methods of synthesizing the compounds are also disclosed. Also disclosed are pharmaceutical compositions containing a compound of the invention and a method of treating a patient for an autoimmune or an inflammatory disease or disorder, for example, a cancer, by administering a compound of the invention.
    Type: Application
    Filed: July 28, 2017
    Publication date: September 12, 2019
    Inventors: Gagan Kukreja, Nageswara Rao Irlapati, Arun Rangnath Jagdale, Gokul Keruji Deshmukh, Vinod Popatrao Vyavahare, Kiran Chandrashekhar Kulkarni, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS
    Publication number: 20190160045
    Abstract: Disclosed are compounds of the general formula (I), wherein R1-R3 are as defined herein, for use as MALT1 inhibitors in the treatment of autoimmune and inflammatory diseases or disorders. Methods of synthesizing the compounds are also disclosed. Also disclosed are pharmaceutical compositions containing a compound of the invention and a method of treating a patient for an autoimmune or an inflammatory disease or disorder, for example, a cancer, by administering a compound of the invention.
    Type: Application
    Filed: July 28, 2017
    Publication date: May 30, 2019
    Inventors: Gagan Kukreja, Nageswara Rao Irlapati, Arun Rangnath Jagdale, Gokul Keruji Deshmukh, Vinod Popatrao Vyavahare, Kiran Chandrashekhar Kulkarni, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • Chromane and chromene derivatives and their use as CRAC modulators
    Patent number: 9790231
    Abstract: The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators.
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: October 17, 2017
    Assignee: LUPIN LIMITED
    Inventors: Nageswara Rao Irlapati, Kiran Chandrashekhar Kulkarni, Vijay Pandurang Karche, Gokul Keruji Deshmukh, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED PYRAZOLE COMPOUNDS AS CRAC MODULATORS
    Publication number: 20160304507
    Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.
    Type: Application
    Filed: June 28, 2016
    Publication date: October 20, 2016
    Inventors: Nageswara Rao IRLAPATI, Gokul Keruji DESHMUKH, Nilesh Raghunath KHEDKAR, Kiran Chandrashekhar KULKARNI, Zubair Abdul Wajid SHAIKH, Neelima SINHA, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • Substituted pyrazole compounds as CRAC modulators
    Patent number: 9409898
    Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: August 9, 2016
    Assignee: LUPIN LIMITED
    Inventors: Nageswara Rao Irlapati, Gokul Keruji Deshmukh, Nilesh Raghunath Khedkar, Kiran Chandrashekhar Kulkarni, Zubair Abdul Wajid Shaikh, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj
  • CHROMANE AND CHROMENE DERIVATIVES AND THEIR USE AS CRAC MODULATORS
    Publication number: 20160137659
    Abstract: The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators.
    Type: Application
    Filed: June 23, 2014
    Publication date: May 19, 2016
    Inventors: Nageswara Rao IRLAPATI, Kiran Chandrashekhar KULKARNI, Vijay Pandurang KARCHE, Gokul Keruji DESHMUKH, Neelima SINHA, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • SUBSTITUTED PYRAZOLE COMPOUNDS AS CRAC MODULATORS
    Publication number: 20150111925
    Abstract: The present invention relates to compounds described herein Formula (I) and pharmaceutical acceptable salts thereof, which modulate the activity of calcium release-activated calcium (CRAC) channel. The invention also describes the compounds of Formula (I) and pharmaceutical compositions containing such compounds thereof for treating, managing, and/or lessening the severity of diseases, disorders, syndromes or conditions associated with the modulation of calcium release-activated calcium (CRAC) channel.
    Type: Application
    Filed: May 1, 2013
    Publication date: April 23, 2015
    Inventors: Nageswara Rao Irlapati, Gokul Keruji Deshmukh, Nilesh Raghunath Khedkar, Kiran Chandrashekhar Kulkarni, Zubair Abdul Wajid Shaikh, Neelima Sinha, Venkata P. Palle, Rajender Kumar Kamboj