Abstract: The present invention relates to a device, system and method for detection of pulse and/or pulse-related information of a patient.

Abstract: According to an aspect, there is provided a method comprising: receiving (402), from a sensor, first data indicative of a concentration of a first substance in sweat secreted from sweat glands of a subject; determining (404) a relationship between (i) a time of occurrence of a characteristic event in relation to the concentration of the first substance in sweat and (ii) a time of occurrence of the characteristic event in relation to the concentration of the first substance in blood; and determining (406), based on the relationship and the received first data, a time window regarding the intake of a second substance by the subject. Another aspect provides an apparatus for carrying out this method.

Abstract: Provided is a system (300) for determining a sweat rate per gland and measuring biomarker concentration. The system comprises an apparatus and a sensor (166). The apparatus receives sweat from the skin and transports the sweat as discrete sweat droplets to the sensor. The sensor senses each of the counted sweat droplets. The system further comprises a processor which counts the number of sensed sweat droplets during a time period. The processor also determines time intervals between consecutive sensed sweat droplets, and receives a measure of the volume of each of the counted sweat droplets. The time intervals and the measure of the volume are then used by the processor to identify sweat burst and rest periods of the sweat gland or glands producing the sweat. This identification process necessarily involves assigning the sweat burst and rest periods to the sweat gland or glands, such that the processor is permitted to determine the number of sweat glands involved in producing the sweat.

Abstract: Provided is an apparatus (100) for transporting sweat droplets (112) to a sensor. The apparatus comprises a chamber (102) for filling with sweat. The chamber has an inlet (104) lying adjacent the surface of the skin (106), which inlet permits sweat to enter and fill the chamber. The chamber has an outlet (114) from which a sweat droplet protrudes once the chamber has been filled. The apparatus further comprises a fluid transport assembly which is designed to enable the sweat droplet protruding from the outlet to become detached from the outlet of the chamber. The sweat droplet is subsequently transported by the fluid transport assembly to the sensor. Once the protruding droplet has been released from the outlet, the outlet is made available for a subsequent sweat droplet to protrude therefrom upon further filling of the chamber.

Abstract: A wearable patch system comprises a sensor (14) for measuring at least one sweat parameter, and a controller (16) for indicating the need to replace the patch. The controller is configured to receive the at least one sweat parameter and compare the at least one sweat parameter to a first threshold. The controller is also configured to determine the replacement information based on the total amount of time during which the at least one sweat parameter exceeds the first threshold; and/or a value indicative of the at least one sweat parameter in respect of the total amount of time during which the at least one sweat parameter exceeds the first threshold. The controller is further configured to output an indication that the wearable patch needs (12) replacing based on the replacement information.

Abstract: The present invention relates to a device, system and method for improved non-invasive and objective detection of pulse of a subject. The device comprises an input unit (2a) configured to obtain a series of images of a skin region of the subject and a processing unit (2b) for processing said series of images by detecting pulse-related motion of the skin within the skin region from the series of images, generating a motion map of the skin region from the detected pulse-related motion, comparing the generated motion map with an expected motion map of the skin region, and determining the presence of pulse within the skin region based on the comparison.

Abstract: A breast pump device (1) is equipped with or used in conjunction with an acoustic milk expression assessment system (6) for the purpose of obtaining an indication about a fat content of expressed milk. The acoustic milk expression assessment system (6) includes an acoustic sensor (61) and a processor (62) configured to process an acoustic signal received from the acoustic sensor (61) during operation of the breast pump device (1) when a milk receptacle (4) is used with the device (1). By recording sound during a pumping session, it is possible to determine a frequency shift in the sound of droplets falling down in the receptacle (4) and hitting a surface of the milk contained by the receptacle (4) with respect to a reference situation of a liquid having 0% fat content, which can be taken as a factor in estimating a value related to the fat content of the milk.

Abstract: According to an aspect, there is provided a system (10) comprising a sweat stimulation device (100) for stimulating sweat generation from sweat glands of a subject, the device comprising: a stimulation element (102) configured to provide modulated stimulation between two non-zero states to the sweat glands through the skin of the subject; and a sensor (104) for measuring data indicative of a characteristic of sweat generated by the sweat glands in response to the stimulation; and a processor (110) configured to receive the measured data from the sensor; compare the measured data with a threshold value; and responsive to determining that the measured data meets or exceeds the threshold value, generate an alert signal.

Abstract: Provided are concepts for generating an indicator of chronic obstructive pulmonary disease (COPD) in a subject. In particular, data from a plurality of sensors, including a pressure sensor, an airflow sensor, and a CO2 concentration sensor is captured from the breath of the subject received by a mouthpiece. The sensor data is then utilised by a processing unit to generate an indicator of COPD in the subject. By utilising airway pressure, airway flow rate and expiratory CO2 concentration data, an accurate indicator of the presence and/or stage of COPD may be obtained.

Abstract: Provided are concepts for controlling a high flow nasal therapy (HFNT) device used by a subject. In particular, physiological and movement parameter values of the subject are leveraged in order to generate a control signal for the HFNT device. These parameters may indicate an activity level of the subject, as well as the condition of the subject, providing information useful for setting appropriate operating conditions of the HFNT device. Thus, a means for automatically controlling a HFNT device based on needs of the subject may be provided, improving subject comfort during therapy, and ease of use of the HFT device.

Abstract: The present invention relates to body fluid monitoring. It is proposed to incorporate a reagent-free calibration method into a patch or wearable. The method comprises capturing molecules of interest, i.e. calibration molecules inside the bioliquid of the patient, and release them when needed for calibration. This eliminates the need for onboard reagent storage. Because the calibration is done in the same bioliquid, any matrix effects are corrected for.

Abstract: A computer-implemented method and corresponding output generator for handling alarm events, generated by a subject/patient monitoring device, and generating clinician-perceptible outputs indicative of the alarm events. Alarm events are divided into non-actionable and actionable alarm events. Information on non-actionable alarm events is stored. Stored information on non-actionable alarm events is contained in a clinician-perceptible output generated in response to detecting an actionable alarm event.

Abstract: The present invention relates to devices and methods for uptaking and analyzing sweat from a skin of a user. In particular, it is proposed to provide a variability in the size of the sweat sensor inlets (102, 103, 104), which can be used for improving the determination of sweat parameters like for example determining the number of active sweat glands The variability in the size of the inlets (102, 103, 104) with which the sweat sensor (100) uptakes the sweat from the user's skin (111) can be achieved by having either plurality of inlets wherein at least some of them have different opening sizes and to use the differently sized inlets based in different situations. Alternatively, one or more inlets may have openings with variable cross-sectional area, like e.g. an adjustable diameter of their opening, and also a combination of these two alternatives is of course possible.

Abstract: A respiration monitoring device comprises an electronic controller configured to: receive an audio signal that is acoustically coupled with an airway of a patient receiving mechanical ventilation therapy from a mechanical ventilator; map the audio signal to one or more lung disease or injury condition categories; and at least one of: display the mapped one or more lung disease or injury condition categories on a display device; and determine a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient based at least on the mapped lung disease or injury condition categories and displaying the recommended adjustment on the display device.

Abstract: A mechanical insufflation-exsufflation device including an air source to provide positive airway pressure (PAP); a patient interface; at least one sensor to sense air pressure and flow at the patient interface; and a controller to control the air source to deliver at least one mechanically assisted cough to the patient in response to at least one of a target breathing flow and a target inhalation time period being sensed by the at least one sensor, and when the at least one of a target breathing flow and a target inhalation time period is not sensed, the controller is configured to control the air source to deliver each in a series of high-level PAP provided over a duration being followed by a low-level PAP provided over a duration, the series of high-level PAP increasing in pressure level and duration from a prior one in the series of high-level PAP.

Abstract: A respiratory monitoring device includes an electronic controller configured to: analyze an audio signal triggered during inspiratory and expiratory phases of a patient receiving mechanical ventilation therapy from a mechanical ventilator, the audio signal being acoustically coupled into the airway of the patient, to determine resonant frequencies of the airway; determine a shift in the resonant frequencies between the inspiratory and expiratory phases to determine a presence of pendelluft inside of a lung of the patient; and output an indication of the presence of pendelluft.

Abstract: A mechanical ventilation device comprises at least one electronic controller configured to: receive ultrasound data related to a thickness of a diaphragm of a patient during inspiration and expiration while the patient undergoes mechanical ventilation therapy with a mechanical ventilator; calculate a diaphragm thickness metric based on at least the ultrasound data; and when the calculated diaphragm thickness metric does not satisfy an acceptance criterion, at least one of: output an alert indicative of the calculated diaphragm thickness metric failing to satisfy the acceptance criterion; and output a recommended adjustment to one or more parameters of the mechanical ventilation therapy delivered to the patient.

Abstract: An intubation assistance device includes an electronic controller configured to: generate a patient respiratory tract geometry model of at least a portion of a human respiratory tract by inputting one or more patient variables into a statistical shape model (SSM) of at least a portion of the human respiratory tract; select a recommended endotracheal tube (ETT) size by modeling at least one ETT model inserted into the patient respiratory tract geometry model to form a virtual fit model and estimating at least one fit parameter based on the virtual fit model; and display the recommended ETT size on a display device.

Abstract: A cough detection system and method uses a first database of physiological information relating to a user for whom cough detection is to be implemented and relating to other people likely to be in the vicinity of the user. A second database (used in real time or as a part of a system calibration) has cough data associated with the physiological information. There is a set of cough detection algorithms, each one tailored to a particular set of physiological characteristics. A cough detection algorithm is selected or constructed which is suitable for identifying coughs of the user while ignoring coughs of the other people. This selected algorithm is applied to sound collected to identify coughs of the user.

Abstract: An intubation assistance device includes an electronic controller configured to: identify, from one or more images of a patient, information about the patient including at least a diameter of a trachea and a length of an intubation pathway; determine a recommended ETT size including an ETT diameter and an ETT depth of insertion from the determined diameter of the trachea and the determined length of the intubation pathway; and display the recommended ETT size on a display device.