Patents by Inventor Kiran Madura

Kiran Madura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and kits for detecting mastitis
    Patent number: 9422591
    Abstract: Methods and kits for determining if one or more animals have mastitis and for monitoring animals and the quality of the milk they produce are disclosed. Kits and test assays disclosed are used to determine the quantity of proteasomes and proteins thereof, the activity of proteasome enzymes, the quantity of proteasome bound and regulating proteins, and the quantity of ubiquinated protein. Components and reagents for use in the kits and assays are also disclosed.
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: August 23, 2016
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventor: Kiran Madura
  • Methods and kit for detecting breast cancer
    Patent number: 8889365
    Abstract: The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: November 18, 2014
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Kiran Madura, Li Chen
  • METHODS AND KITS FOR DETECTING MASTITIS
    Publication number: 20140206010
    Abstract: Methods and kits for determining if one or more animals have mastitis and for monitoring animals and the quality of the milk they produce are disclosed. Kits and test assays disclosed are used to determine the quantity of proteasomes and proteins thereof, the activity of proteasome enzymes, the quantity of proteasome bound and regulating proteins, and the quantity of ubiquinated protein. Components and reagents for use in the kits and assays are also disclosed.
    Type: Application
    Filed: July 26, 2012
    Publication date: July 24, 2014
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventor: Kiran Madura
  • Diagnostic methods for ubiquinated protein profiling
    Patent number: 8614303
    Abstract: Methods for establishing a protein expression profile of a biological sample, by contacting a biological sample with a ubiquitin-binding protein such that ubiquitinated and specific non-ubiquitinated protein (the IPS) bind to the ubiquitin-binding protein; isolating the IPS proteins; and analyzing the isolated IPS proteins, wherein an expression profile is generated.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: December 24, 2013
    Assignee: University of Medicine and Dentistry
    Inventors: Kiran Madura, Li Chen
  • Methods of detecting mastitis by levels of proteasomes
    Patent number: 8183047
    Abstract: Method and systems for determining if one or more animals has mastitis and for monitoring animals and the quality of the milk they produce are disclosed. Systems and test assays disclosed are used to determine the quantity of proteasomes and proteins thereof, the activity of proteasome enzymes, the quantity of proteasome bound and regulating proteins, and the quantity of ubiquinated protein. Components and reagents for use in the systems and assays are also disclosed.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: May 22, 2012
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventor: Kiran Madura
  • Methods and Kit for Detecting Breast Cancer
    Publication number: 20120028271
    Abstract: The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer.
    Type: Application
    Filed: August 8, 2011
    Publication date: February 2, 2012
    Applicant: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
    Inventors: KIRAN MADURA, LI CHEN
  • Methods and Kits for Detecting Mastitis
    Publication number: 20120003662
    Abstract: Methods and kits for determining if one or more animals have mastitis and for monitoring animals and the quality of the milk they produce are disclosed. Kits and test assays disclosed are used to determine the quantity of proteasomes and proteins thereof, the activity of proteasome enzymes, the quantity of proteasome bound and regulating proteins, and the quantity of ubiquinated protein. Components and reagents for use in the kits and assays are also disclosed.
    Type: Application
    Filed: July 26, 2011
    Publication date: January 5, 2012
    Applicant: University of Medicine and Dentistry of New Jersey
    Inventor: Kiran Madura
  • Methods and kit for detecting breast cancer
    Patent number: 8008022
    Abstract: The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: August 30, 2011
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventors: Kiran Madura, Li Chen
  • Methods and compositions for rapid purification of proteasomes and methods of use of components thereof
    Patent number: 7811803
    Abstract: Disclosed are methods for rapidly and efficiently purifying proteasomes using fusion proteins having homology to ubiquitin. Also disclosed are methods for assessing aberrant cell growth utilizing fusion proteins have homology to ubiquitin and a signal producing moiety.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: October 12, 2010
    Assignee: University of Medicine and Dentistry of New Jersey
    Inventor: Kiran Madura
  • Systems for and Methods of Detecting Mastitis
    Publication number: 20100210022
    Abstract: Method and systems for determining if one or more animals has mastitis and for monitoring animals and the quality of the milk they produce are disclosed. Systems and test assays disclosed are used to determine the quantity of proteasomes and proteins thereof, the activity of proteasome enzymes, the quantity of proteasome bound and regulating proteins, and the quantity of ubiquinated protein. Components and reagents for use in the systems and assays are also disclosed.
    Type: Application
    Filed: October 20, 2008
    Publication date: August 19, 2010
    Inventor: Kiran Madura
  • Methods and Kit for Detecting Breast Cancer
    Publication number: 20090246794
    Abstract: The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer.
    Type: Application
    Filed: March 15, 2006
    Publication date: October 1, 2009
    Inventors: Kiran Madura, Li Chen
  • Methods and compositions for rapid purification of proteasomes and methods of use of components thereof
    Publication number: 20060281118
    Abstract: Disclosed are methods for rapidly and efficiently purifying proteasomes using fusion proteins having homology to ubiquitin. Also disclosed are methods for assessing aberrant cell growth utilizing fusion proteins have homology to ubiquitin and a signal producing moiety.
    Type: Application
    Filed: May 30, 2006
    Publication date: December 14, 2006
    Inventor: Kiran Madura
  • Diagnostic methods for protein profiling
    Publication number: 20050287608
    Abstract: Methods for establishing a protein expression profile of a biological sample, by contacting a biological sample with a ubiquitin-binding protein such that ubiquitinated and specific non-ubiquitinated protein (the IPS) bind to the ubiquitin-binding protein; isolating the IPS proteins; and analyzing the isolated IPS proteins, wherein an expression profile is generated.
    Type: Application
    Filed: December 11, 2002
    Publication date: December 29, 2005
    Inventors: Kiran Madura, Li Chen
  • Methods and compositions for rapid purification of proteasomes and methods of use of components thereof
    Publication number: 20030092159
    Abstract: Disclosed are methods for rapidly and efficiently purifying proteasomes using fusion proteins having homology to ubiquitin. Also disclosed are methods for assessing aberrant cell growth rates utilizing fusion proteins have homology to ubiquitin and a signal producing moiety.
    Type: Application
    Filed: July 30, 2001
    Publication date: May 15, 2003
    Inventor: Kiran Madura
  • Rapid method of proteasome purification using proteins having sequence homology to ubiquitin
    Patent number: 6294363
    Abstract: Disclosed are methods for rapidly and efficiently purifying proteasomes using fusion proteins having homology to ubiquitin using amino acid sequences adhered to a solid support.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: September 25, 2001
    Assignee: University of Medicine & Dentistry of New Jersey
    Inventor: Kiran Madura