Patents by Inventor Kiran Sonaje

Kiran Sonaje has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mucoadhesive preparations, methods and applications thereof
    Patent number: 11491107
    Abstract: The present disclosure relates to mucoadhesive preparation comprising chitosan, and methods thereof. Further, the present disclosure relates to applications of the mucoadhesive preparation.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: November 8, 2022
    Assignee: AXIO BIOSOLUTIONS PVT. LTD.
    Inventors: Leo Mavely, Kiran Sonaje, Indu A. G.
  • COMPOSITE DRESSINGS, MANUFACTURING METHODS AND APPLICATIONS THEREOF
    Publication number: 20210252182
    Abstract: The present disclosure provides a composite dressing comprising a combination of porous matrix and fabric substrate wherein at least one of said porous matrix and fabric substrate is composed biomaterial(s) and wherein the fabric substrate is at least partially embedded in the porous matrix. Further, the disclosure provides a method for preparation of said composite dressing, wherein said method enables production of the composite dressing having cohesive bonding between porous matrix and fabric support without use of any adhesive, stitching or chemical crosslinking agent between the two layers. The composite dressing exhibits high peel strength in both dry and wet conditions and has applications such as hemostatic dressings for deep cavity wounds, puncture wounds, post-partum hemorrhage and internal hemostatic agents.
    Type: Application
    Filed: August 27, 2019
    Publication date: August 19, 2021
    Inventors: Leo MAVELY, Kiran SONAJE, Animesh AGRAWAL
  • MUCOADHESIVE PREPARATIONS, METHODS AND APPLICATIONS THEREOF
    Publication number: 20190254956
    Abstract: The present disclosure relates to mucodhesive preparation comprising chitosan, and methods thereof. Further, the present disclosure relates to applications of the mucoadhesive preparation.
    Type: Application
    Filed: November 3, 2017
    Publication date: August 22, 2019
    Applicant: AXIO BIOSOLUTIONS PVT. LTD.
    Inventors: Leo MAVELY, Kiran SONAJE, Indu A.G.
  • Pharmaceutical composition of nanoparticles
    Patent number: 8383082
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: August 21, 2012
    Date of Patent: February 26, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8361439
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: January 29, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Zi-Xian Liao, Ha Giang Thi Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8354094
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: August 20, 2012
    Date of Patent: January 15, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Zi-Xian Liao, Ha Giang Thi Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8349799
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for drug delivery.
    Type: Grant
    Filed: June 16, 2012
    Date of Patent: January 8, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8337811
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: December 25, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8287905
    Abstract: The invention discloses a composition of chitosan-shelled nanoparticles and methods of manufacturing. The chitosan-shelled nanoparticles are characterized with a positive surface charge and enhanced epithelial permeability for oral drug delivery.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: October 16, 2012
    Assignees: GP Medical, Inc., National Tsing Hua Univresity
    Inventors: Hsing-Wen Sung, Er-Yuan Chuang, Ha Giang Thi Nguyen, Fang Yi Su, Kiran Sonaje, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8257740
    Abstract: The invention discloses a composition of chitosan-shelled nanoparticles and methods of manufacturing. The chitosan-shelled nanoparticles are characterized with a positive surface charge and enhanced epithelial ermeability for oral drug delivery.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: September 4, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Hosheng Tu
  • PHARMACEUTICAL COMPOSITION OF NANOPARTICLES
    Publication number: 20120207845
    Abstract: The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8236752
    Abstract: The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: August 7, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8236281
    Abstract: The invention relates to a pharmaceutical composition of nanoparticles, wherein the nanoparticles comprise positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating diabetes of an animal subject.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: August 7, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8226928
    Abstract: The invention discloses nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent, wherein the bioactive agent may include mitofusin 1, mitofusin 2, and/or anti-diabetic compounds.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: July 24, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Ha Giang Thi Nguyen, Fang Yi Su, Er-Yuan Chuang, Hosheng Tu
  • Composition of imaging nanoparticles
    Patent number: 8221795
    Abstract: The invention relates to a method of managing a tumor of an animal subject comprising imaging the tumor by delivering a dosage of imaging nanoparticles to the tumor site, the imaging nanoparticles consisting of positively charged chitosan, optionally a zero-charge substance or bioactive agent, and a negatively charged substrate having gadolinium (Gd) chelated to the negatively charged substrate.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 17, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8202839
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: January 7, 2012
    Date of Patent: June 19, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles for protein drug delivery
    Patent number: 8202508
    Abstract: The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: June 19, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Pharmaceutical composition of nanoparticles
    Patent number: 8192718
    Abstract: The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: June 5, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • PHARMACEUTICAL COMPOSITION OF PEPTIDE DRUG AND ENZYME-INHIBITION COMPOUNDS
    Publication number: 20120121701
    Abstract: The invention relates to a method of co-administering a peptide or protein drug with an enzyme-resistant PGA-complexone compound orally so to mitigate enzyme attack in the gastrointestinal tract of an animal subject.
    Type: Application
    Filed: December 13, 2011
    Publication date: May 17, 2012
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Hosheng Tu
  • Pharmaceutical composition of peptide drug and enzyme-inhibition compounds
    Patent number: 8173106
    Abstract: The invention relates to a method of co-administering a peptide or protein drug with an enzyme-resistant PGA-complexone compound orally so to mitigate enzyme attack in the gastrointestinal tract of an animal subject.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: May 8, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Hosheng Tu