Patents by Inventor Kirill Kolmakov

Kirill Kolmakov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220107325
    Abstract: Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone sulfonamides or 1-aminopyrenes having of one of the following general formulae A-D: Formula (A), Formula (B), Formula (C), Formula (D), wherein the ionizable groups X are typically selected from the following: SH, COOH, SO3H, OSO3H, OP(O)(OH)2, OP(O)(OH)Ra, P(O)(OH)2, P(O)(OH)Ra, where Ra?C1-C4alkyl or substituted C1-C4alkyl. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans.
    Type: Application
    Filed: January 21, 2019
    Publication date: April 7, 2022
    Inventors: Stefan W. HELL, Vladimir N. BELOV, Matthias BISCHOFF, Dirk MEINEKE, Laura THOMAS, Gyuzel MITRONOVA, Elizaveta SAVICHEVA, Kirill KOLMAKOV, Marvin J. BOEHM, Erdmann RAPP, René HENNIG
  • Publication number: 20220026434
    Abstract: The present invention relates to improved (simplified/easier, more robust and more reproducible) methods for identification of carbohydrates compositions, e.g. out of complex carbohydrate mixtures, as well as the determination of carbohydrate mixture composition patterns (e.g.: of glycosylation patterns) based on advanced internal standards to determine precise and highly reproducible migration and retention time indices using novel fluorescent dyes in combination with high performance separation technologies, like capillary (gel) electrophoresis (C(G)E) or (ultra)high performance liquid chromatography (U)HPLC with a highly sensitive detection like (laser induced) fluorescence detection.
    Type: Application
    Filed: January 21, 2019
    Publication date: January 27, 2022
    Inventors: Erdmann RAPP, René HENNIG, Udo REICHL, Stefan HELL, Vladimir BELOV, Matthias BISCHOFF, Dirk MEINEKE, Laura THOMAS, Kirill KOLMAKOV, Gyuzel MITRONOVA, Elizaveta SAVICHEVA
  • Publication number: 20190367737
    Abstract: The invention relates to novel cell-penetrating fluorescent dyes with secondary alcohol functionalities having one of the following general formulae I-III and 4: The invention also relates to the use of these compounds for optical microscopy and imaging techniques.
    Type: Application
    Filed: September 12, 2017
    Publication date: December 5, 2019
    Inventors: Alexey BUTKEVICH, Vladimir N. BELOV, Stefan W. HELL, Dirk KAMIN, Sven SIDENSTEIN, Heydar SHOJAEI, Kirill KOLMAKOV, Viktor V. SOKOLOV
  • Patent number: 9523678
    Abstract: The invention relates to novel fluorescent dyes with phosphorylated hydroxymethyl groups, a method for preparing the same as well as to their use in imaging techniques. The fluorescent dyes are coumarin, rhodamine or BODIPY dyes having of one of the following general formulae I-III: wherein W=OP(O)Y1Y2 or P(O)Y1Y2, where Y1 and Y2 independently denote any of the following residues: OH, O(?), ORa and ORb, NHRa and NHRb, NRaRb and NRcRd, ORa and NHRb, ORa and NRbRc, NHRa and NRbRc; and any salt thereof.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: December 20, 2016
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Stefan W. Hell, Shamil Nizamov, Gerald Donnert, Kirill Kolmakov, Heiko Schill, Lars Kastrup, Christian A. Wurm, Vladimir N. Belov, Johanna Wildanger, Katrin Willig
  • Publication number: 20160047798
    Abstract: The invention relates to novel fluorescent dyes with phosphorylated hydroxymethyl groups, a method for preparing the same as well as to their use in imaging techniques. The fluorescent dyes are coumarin, rhodamine or BODIPY dyes having of one of the following general formulae I-III: wherein W=OP(O)Y1Y2 or P(O)Y1Y2, where Y1 and Y2 independently denote any of the following residues: OH, O(?), ORa and ORb, NHRa and NHRb, NRaRb and NRcRd, ORa and NHRb, ORa and NRbRc, NHRa and NRbRc; and any salt thereof.
    Type: Application
    Filed: August 18, 2015
    Publication date: February 18, 2016
    Inventors: Stefan W. HELL, Shamil NIZAMOV, Gerald DONNERT, Kirill KOLMAKOV, Heiko SCHILL, Lars KASTRUP, Christian A. WURM, Vladimir N. BELOV, Johanna WILDANGER, Katrin WILLIG
  • Patent number: 9164086
    Abstract: The invention relates to novel fluorescent dyes with phosphorylated hydroxymethyl groups, a method for preparing the same as well as to their use in imaging techniques. The fluorescent dyes are coumarin, rhodamine or BODIPY dyes having of one of the following general formulae I-III: wherein W=OP(O)Y1Y2 or P(O)Y1Y2, where Y1 and Y2 independently denote any of the following residues: OH, O(?), ORa and ORb, NHRa and NHRb, NRaRb and NRcRd, ORa and NHRb, ORa and NRbRc, NHRa and NRbRc; and any salt thereof.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: October 20, 2015
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Stefan W. Hell, Shamil Nizamov, Gerald Donnert, Kirill Kolmakov, Heiko Schill, Lars Kastrup, Christian A. Wurm, Vladimir N. Belov, Johanna Wildanger, Katrin Willig
  • Publication number: 20140220588
    Abstract: The invention relates to novel fluorescent dyes with phosphorylated hydroxymethyl groups, a method for preparing the same as well as to their use in imaging techniques. The fluorescent dyes are coumarin, rhodamine or BODIPY dyes having of one of the following general formulae I-III: wherein W=OP(O) Y1Y2 or P(O) Y1Y2, where Y1 and Y2 independently denote any of the following residues: OH, O(?), ORa and ORb, NHRa and NHRb, NRaRb and NRcRd, ORa and NHRb, ORa and NRbRc, NHRa and NRbRc; and any salt thereof.
    Type: Application
    Filed: October 18, 2011
    Publication date: August 7, 2014
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Stefan W. Hell, Shamil Nizamov, Gerald Donnert, Kirill Kolmakov, Heiko Schill, Lars Kastrup, Christian A. Wurm, Vladimir N. Belov, Johanna Bueckers, Katrin Willig
  • Patent number: 8580579
    Abstract: The invention relates to novel and improved photostable rhodamine dyes of the general structural formulae I or II and their uses as fluorescent markers, e.g. for immunostainings and spectroscopic and microscopic applications, in particular in conventional and stimulated emission depletion (STED) microscopy and fluorescence correlation spectroscopy.
    Type: Grant
    Filed: April 26, 2010
    Date of Patent: November 12, 2013
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Stefan Hell, Vladimir N. Belov, Kirill Kolmakov, Volker Westphal, Marcel Lauterbach, Stefan Jakobs, Christian Wurm, Christian Eggeling, Christian Ringemann
  • Publication number: 20120100559
    Abstract: The invention relates to novel and improved photostable rhodamine dyes of the general structural formulae I or II and their uses as fluorescent markers, e.g. for immunostainings and spectroscopic and microscopic applications, in particular in conventional and stimulated emission depletion (STED) microscopy and fluorescence correlation spectroscopy. The partially deuterated analogues are useful as molecular mass distribution tags in mass spectroscopic applications.
    Type: Application
    Filed: April 26, 2010
    Publication date: April 26, 2012
    Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventors: Stefan Hell, Vladimir N. Belov, Kirill Kolmakov, Volker Westphal, Marcel Lauterbach, Stefan Jakobs, Christian Wurm, Christian Eggeling, Christian Ringemann