Abstract: This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.

Abstract: A method for identifying nucleic acid ligands to target molecules using the SELEX pocedure wherein the candidate nucleic acids contain photoreactive groups and nucleic acid ligands identified thereby are claimed. The complexes of increased affinity nucleic acids and target molecules formed in the procedure are crosslinked by irradiation to facilitate separation from unbound nucleic acids. In other methods partioning of high and low affinity nucleic acids is facilitated by primer extension steps as shown in the figure in which chain termination nucleotides, digestion resistant nucleotides or nucleotides that allow retention of the cDNA product on an affinity matrix are differentially incorporated into the cDNA products of either the high or low affinity nucleic acids and the cDNA products are treated accordingly to amplification, enzymatic or chemical digestion or by contact with an affinity matrix.

Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.

Abstract: This application provides methods for identifying nucleic acid ligands capable of covalently interacting with targets of interest. The nucleic acids can be associated with various functional units. The method also allows for the identification of nucleic acids that have facilitating activities as measured by their ability to facilitate formation of a covalent bond between the nucleic acid, including its associated functional unit, and its target.

Abstract: A sun visor or other accessory for a motor vehicle. The sun visor includes a body made of rigid foam in which various structures (such as a support pin, detent and pivot arm) are insert molded. The foam has a rigidity which is sufficient to support said sun visor without requiring any additional reinforcing structures such as a support frame, support wire or centerboard. The pivot arm and detent are provided within a casing that prevents the foam from affecting the operation of the detent. Also insert molded into the body of the visor are mounts for an illuminated vanity. Terminals from a power supply are mounted in predetermined positions relative to the body so that when the vanity is mounted to the body, contacts coupled to a lamp and mounted to the vanity in predetermined positions, are caused engage the terminals.

Abstract: A sun visor or other accessory for a motor vehicle. The sun visor includes a body made of rigid foam in which various structures (such as a support pin, detent and pivot arm) are insert molded. The foam has a rigidity which is sufficient to support said sun visor without requiring any additional reinforcing structures such as a support frame, support wire or centerboard. The pivot arm and detent are provided within a casing that prevents the foam from affecting the operation of the detent. Also insert molded into the body of the visor are mounts for an illuminated vanity. Terminals from a power supply are mounted in predetermined positions relative to the body so that when the vanity is mounted to the body, contacts coupled to a lamp and mounted to the vanity in predetermined positions, are caused engage the terminals.

Abstract: An exemplary accessory assembly for a vehicle interior is adapted in its preferred embodiments for receiving and holding generally cylindrical items, such as liquid beverage containers, having different diameters or shapes. Such an accessory assembly includes a generally hollow, cylindrical base portion and a generally hollow, cylindrical receptacle slidably disposed therein for axial movement at least between extended and retracted positions.

Abstract: Snap-in installation double latch release bracket for retaining passenger car cargo cover end caps.