Abstract: The present invention is a double-bowed ice skate blade having an attachment section with a constant thickness and a blade section with a continually variable thickness, with the thickest segments occurring at the toe-end and heel-end of the blade. The center section of the contoured ice skate blade has a large radius, creating a flatter blade with a greater length of the blade in contact with the ice. At the toe-end and heel-end of the contoured ice skate blade, the radius of the blade is smaller, resulting in a more curved blade, and less length of the ice-contacting surface of the blade in physical contact with the ice. Because the segments of smaller radius are thicker, a greater cross-sectional area of the ice-contacting surface of the blade is in contact with the ice at the toe-end and heel-end of the blade.

Abstract: The present invention relates to compounds of the formula (I) and pharmaceutically acceptable salts and solvates thereof, wherein the substituents are defined herein, to compositions containing such compounds and to the uses of such compounds for the treatment of allergic and respiratory conditions.