Patents by Inventor Kirk Schnorr
Kirk Schnorr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7029842Abstract: The present invention allows the screening of previously established genebanks or libraries by proxy for genes encoding secreted, partially secreted, or cell surface-displayed polypeptides of industrial interest, such as enzymes, receptors, cytokines, peptide hormones etc. that would not likely have been isolated using conventional screening assays. A method for isolating genes encoding secreted, partially secreted, or cell surface displayed polypeptides from existing gene libraries is described in which the endogenous secretion signal sequences are detected using an in vitro polynucleotide insertion reaction where the inserted polynucleotide comprises a promoter-less and secretion signal-less secretion reporter.Type: GrantFiled: March 30, 2001Date of Patent: April 18, 2006Assignee: Novozymes A/SInventors: Fiona Duffner, Reinhard Wilting, Kirk Schnorr
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Publication number: 20060014149Abstract: A method for isolating a polynucleotide that encodes a polypeptide of interest which comprises a signal sequence for secretion or partial secretion, utilizing rolling circle amplification and signal trapping of libraries.Type: ApplicationFiled: August 1, 2003Publication date: January 19, 2006Applicant: Novozymes A/SInventor: Kirk Schnorr
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Publication number: 20050228042Abstract: The present invention relates to compounds with structures resembling natural statins isolated from Penicillium sp. (Formula I); where R1 represents OH, C6H5COO, R6COO and R6 represents C1-C5 alkyl; R2-4 represents H, C1-C5 alkyl C1-C5 acyl, R5 represents H, CH3; and X represents a compound of (Formula II) or (Formula III).Type: ApplicationFiled: December 3, 2002Publication date: October 13, 2005Applicants: Novozymes A/S, Technical University of Denmark, Kobenhavns AmtInventors: Jens Frisvad, Lene Lange, Kirk Schnorr, Steen Stender, Steen Stender, Thomas Larsen
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Publication number: 20050170350Abstract: Methods for screening a polynucleotide library for a polypeptide with a property of interest in a filamentous fungal host cell, in a manner which allows quick and easy subsequent characterization of the polypeptide, using an expression cloning vector comprising at least a polynucleotide encoding a selectable marker in which the translation initiation start site of the marker-encoding sequence comprises a crippled consensus Kozak sequence, a fungal replication initiation sequence, and a promoter with a cloning-site into which the library is cloned, and a transcription terminator.Type: ApplicationFiled: February 18, 2003Publication date: August 4, 2005Inventors: Mary Stringer, Kirk Schnorr, Jesper Vind
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Publication number: 20050124064Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: ApplicationFiled: November 20, 2002Publication date: June 9, 2005Inventors: Kirk Schnorr, Mogens Hansen, Per Mygind, Dorotea Segura, Hans-Henrik Kristensen
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Publication number: 20040266642Abstract: The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30% between pH 5 and pH 8 are derived from the genus Paenibacillus especially from a strain of Paenibacillus polymyxa or Paenibacillus sp. The xyloglucanases exhibit high performance in conventional detergent compositions.Type: ApplicationFiled: July 22, 2004Publication date: December 30, 2004Applicant: Novozymes A/SInventors: Kirk Schnorr, Per Lina Jorgensen, Martin Schulein, Hanne Dela
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Patent number: 6815192Abstract: The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30% between pH 5 and pH 8 are derived from the genus Paenibacillus, especially from a strain of Paenibacillus polymyxa or Paenibacillus sp. The xyloglucanases exhibit high performance in conventional detergent compositions.Type: GrantFiled: February 16, 2001Date of Patent: November 9, 2004Assignee: Novozymes A/SInventors: Kirk Schnorr, Per Lina Jørgensen, Martin Schulein
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Publication number: 20040067572Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: ApplicationFiled: September 4, 2003Publication date: April 8, 2004Applicant: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schulein, Hanne Dela, Niels Erik Krebs Lange, Mads Eskelund Bjornvad, Soren Moller, Sanne O Schroder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6677147Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: February 7, 2002Date of Patent: January 13, 2004Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schroder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Publication number: 20030203466Abstract: The present invention relates to mannanases comprising e.g., a sequence of amino acids 32-330 of SEQ ID NO: 2 or their homologues may be derived from e.g., Bacillus sp. I633, or may be encoded by polynucleotide molecules comprising a sequence of nucleotides 94-990 of SEQ ID NO: 1 from, polynucleotide molecules that encode a polypeptide that is at least 65% identical to the sequence of amino acids 32-330 of SEQ ID NO: 2, or degenerate nucleotide sequences thereof. The mannanases are alkaline and are useful e.g. in cleaning compositions, in a fracturing fluid useful to fracture a subterranean formation, for modifying plant material, and for treatment of cellulosic fibers.Type: ApplicationFiled: February 20, 2003Publication date: October 30, 2003Applicant: Novozymes A/SInventors: Markus Sakari Kauppinen, Martin Schulein, Kirk Schnorr, Lene Nonboe Andersen, Mads Eskelund Bjornvad
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Patent number: 6566114Abstract: Novel mannanases comprising e.g. an amino acid sequence as shown in positions 31-330 of SEQ ID NO:2 or their homologues may be derived from e.g. Bacillus sp. I633, or may be encoded by polynucleotide molecules comprising a nucleotide sequence as shown in SEQ ID NO: 1 from nucleotide 91 to nucleotide 990, polynucleotide molecules that encode a polypeptide that is at least 65% identical to the amino acid sequence of SEQ ID NO: 2 from amino acid residue 31 to amino acid residue 330, or degenerate nucleotide sequences thereof. The mannanases are alkaline and are useful e.g. in cleaning compositions, in a fracturing fluid useful to fracture a subterranean formation, for modifying plant material, and for treatment of cellulosic fibers.Type: GrantFiled: June 24, 1999Date of Patent: May 20, 2003Assignee: Novozymes, A/SInventors: Markus Sakari Kauppinen, Martin Schülein, Kirk Schnorr, Lene Nonboe Andersen, Mads Eskelund Bjørnvad
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Publication number: 20030032162Abstract: The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30% between pH 5 and pH 8 are derived from the genus Paenibacillus, especially from a strain of Paenibacillus polymyxa or Paenibacillus sp. The xyloglucanases exhibit high performance in conventional detergent compositions.Type: ApplicationFiled: February 16, 2001Publication date: February 13, 2003Applicant: Novozymes A/SInventors: Kirk Schnorr, Per Lina Jorgensen, Martin Schulein
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Publication number: 20030026810Abstract: Novel isolated enzymes exhibiting rhamnogalacturonan hydrolase activity and belonging to a glycosyl hydrolase family other than family 28 are obtained and cloned from bacterial strains, for example, Bacillus licheniformis, Bacillus subtilis, Bacillus halodurans, Bacillus agaradhaerens, Caldicellulosiruptor, Streptomyces and Sorangium.Type: ApplicationFiled: April 19, 2002Publication date: February 6, 2003Applicant: Novozymes A/SInventors: Per Lina Jorgensen, Kirk Schnorr, Lene Nonboe Andersen, Martin Schulein, Hanne Dela, Helle Outtrup
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Publication number: 20020142438Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: ApplicationFiled: February 7, 2002Publication date: October 3, 2002Applicant: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schulein, Hanne Dela, Niels Erik Krebs Lange, Mads Eskelund Bjornvad, Soren Moller, Sanne O. Schroder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6429000Abstract: Pectin degrading enzymes derived from or endogeneous to Bacillus licheniformis or other Bacillus species which are at least 99% homologous to Bacillus licheniformis based on aligned 16S rDNA sequences have optimum activity at pH higher than 8. The pectin degrading enzymes belongs to the enzyme classes pectate lyases (EC 4.2.2.2), pectin lyases (EC 4.2.2.10) and polygalacturonases (EC 3.2.1.15) and are useful in industrial processes under alkaline conditions such as in textile processing and as an active ingredient eg in laundry detergents and hard surface cleaning products.Type: GrantFiled: September 26, 2000Date of Patent: August 6, 2002Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Kirk Schnorr
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Publication number: 20020076706Abstract: The present invention allows the screening of previously established genebanks or libraries by proxy for genes encoding secreted, partially secreted, or cell surface-displayed polypeptides of industrial interest, such as enzymes, receptors, cytokines, peptide hormones etc. that would not likely have been isolated using conventional screening assays. A method for isolating genes encoding secreted, partially secreted, or cell surface displayed polypeptides from existing gene libraries is described in which the endogenous secretion signal sequences are detected using an in vitro polynucleotide insertion reaction where the inserted polynucleotide comprises a promoter-less and secretion signal-less secretion reporter.Type: ApplicationFiled: March 30, 2001Publication date: June 20, 2002Applicant: Novozymes A/SInventors: Fiona Duffner, Reinhard Wilting, Kirk Schnorr
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Patent number: 6399351Abstract: A novel pectate lyase belonging to a novel family of polysaccharide lyases has good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: March 15, 2000Date of Patent: June 4, 2002Assignee: Novozymes A/SInventors: Mads Eskelund Bjørnvad, Jens Toenne Andersen, Kirk Schnorr, Martin Schülein, Lars Kongsbak
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Patent number: 6399347Abstract: The present invention is directed to isolated enzymes exhibiting rhamnogalacturonan hydrolase activity, to nucleic acids encoding such enzymes, and to methods of producing such enzymes. The present invention is also related to detergent and animal feed compositions, compositions and methods for treating cellulosic materials, such as fibers, compositions and methods for preparing fruit or vegetable products, and compositions and methods for preparing wine and juice.Type: GrantFiled: May 13, 1999Date of Patent: June 4, 2002Assignee: Novozymes A/SInventors: Per Linå Jørgensen, Kirk Schnorr, Lene Nonboe Andersen, Martin Schülein, Helle Outtrup
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Patent number: 6368843Abstract: A novel group of pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: October 23, 2000Date of Patent: April 9, 2002Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak
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Patent number: 6187580Abstract: A novel group of pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase are derivable from Bacillus species.Type: GrantFiled: November 24, 1998Date of Patent: February 13, 2001Assignee: Novo Nordisk A/SInventors: Lene Nonboe Andersen, Martin Schülein, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak