Abstract: This disclosure provides compositions and methods for high throughput screening, selecting, and identifying antibodies or antibody-like molecules that bind to a target integral membrane protein.

Abstract: Various systems and methods for implementing a software defined industrial system are described herein. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. In response to a node failing, a module may be redeployed to a replacement node. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device and use a module manifest to generate a control system application. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state, which may be changed to an activated state in response an activation signal.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: Various systems and methods for implementing a software defined industrial system are described herein. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. In response to a node failing, a module may be redeployed to a replacement node. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device and use a module manifest to generate a control system application. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state, which may be changed to an activated state in response an activation signal.

Abstract: Various systems and methods are provided for implementing a software defined industrial system. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device, configured to: identify available software modules adapted to perform functional operations in a control system environment; identify operational characteristics that identify characteristics of execution of the available software modules that are available to implement a control system application; select a software module for execution based on the operational configuration and the operational characteristics identified in the manifest; and cause the execution of the selected software module in the control system environment based on an application specification for the control system application.

Abstract: Various systems and methods for implementing a software defined industrial system are described herein. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. In response to a node failing, a module may be redeployed to a replacement node. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device and use a module manifest to generate a control system application. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state, which may be changed to an activated state in response an activation signal.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: Various systems and methods for implementing a software defined industrial system are described herein. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. In response to a node failing, a module may be redeployed to a replacement node. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device and use a module manifest to generate a control system application. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state, which may be changed to an activated state in response an activation signal.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: Various systems and methods for implementing a software defined industrial system are described herein. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. In response to a node failing, a module may be redeployed to a replacement node. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device and use a module manifest to generate a control system application. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state, which may be changed to an activated state in response an activation signal.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state to receive an activation signal from, for example, an orchestration server, and change to an activated state in response to receiving the activation signal.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an edge control node of the industrial system may include a system on a chip including a microcontroller (MCU) to convert IO data. The system on a chip includes a central processing unit (CPU) in an initial inactive state to receive an activation signal from, for example, an orchestration server, and change to an activated state in response to receiving the activation signal.

Abstract: Various systems and methods are provided for implementing a software defined industrial system. In an example, self-descriptive control applications and software modules are provided in the context of orchestratable distributed systems. The self-descriptive control applications may be executed by an orchestrator or like control device, configured to: identify available software modules adapted to perform functional operations in a control system environment; identify operational characteristics that identify characteristics of execution of the available software modules that are available to implement a control system application; select a software module for execution based on the operational configuration and the operational characteristics identified in the manifest; and cause the execution of the selected software module in the control system environment based on an application specification for the control system application.

Abstract: Various systems and methods may be used to implement a software defined industrial system. For example, an orchestrated system of distributed nodes may run an application, including modules implemented on the distributed nodes. The orchestrated system may include an orchestration server, a first node executing a first module, and a second node executing a second module. In response to the second node failing, the second module may be redeployed to a replacement node (e.g., the first node or a different node). The replacement mode may be determined by the first node or another node, for example based on connections to or from the second node.

Abstract: An insole is provided for reducing peak plantar pressure on a foot. The insole includes a compressible pad having a plurality of holes extending from a bottom surface of the compressible pad and partially through the compressible pad. A plurality of compressible plugs is disposed in the plurality of holes, wherein the plurality of compressible plugs has a stiffness that is different than a stiffness of the compressible pad. The plurality of compressible plugs is concentrated in a reduced stiffness portion of the compressible pad that substantially corresponds to an area of peak plantar pressure on the foot.

Abstract: A door mountable infant change table comprising a base structure and a changing area platform structure hingedly attached to each other and capable of vertical mounting on the surface of a door or similar structure through the use of straps secured by brackets to the top and bottom rims of a door or other structure that allow for sliding the change table and securing it to a height suited to the person changing the infant at the change table by means of clips provided near the holes of the change table through which the straps are threaded.

Abstract: A door mountable infant change table comprising a base structure and a changing area platform structure hingedly attached to each other and capable of vertical mounting on the surface of a door or similar structure through the use of straps secured by brackets to the top and bottom rims of a door or other structure that allow for sliding the change table and securing it to a height suited to the person changing the infant at the change table by means of clips provided near the holes of the change table through which the straps are threaded.

Abstract: A system and method to provide secure access across the untrusted public switched telephone network is described. The system and method can be initiated by a security policy defining actions to be taken based upon at least one attribute of the call.