Patents by Inventor Kirsi Bromann

Kirsi Bromann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing terpenes
    Patent number: 10072279
    Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: September 11, 2018
    Assignee: Teknologian tutkimuskeskus VTT Oy
    Inventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
  • Method for producing terpenes
    Publication number: 20160194674
    Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.
    Type: Application
    Filed: May 13, 2013
    Publication date: July 7, 2016
    Applicant: Teknologian tutkimuskeskus VTT
    Inventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
  • Method for producing terpenes
    Patent number: 9238826
    Abstract: The present invention relates to a method for producing terpenes in fungi, wherein a terpene biosynthetic gene cluster having terpene biosynthetic genes and regulatory regions operably linked to said genes is activated. The invention relates also to a terpene biosynthetic gene duster and regulatory regions of such terpene biosynthetic gene cluster usable is production of terpenes, use of regulator for regulating the terpene production and use of Aspergillus nidulans FGSC A4 for producing terpenes. The method of invention provides higher yields of enriched terpene product without essential amount of side-products.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: January 19, 2016
    Assignee: Teknologian Tutkimuskeskus VTT Oy
    Inventors: Kirsi Bromann, Tina Nakari-Setala, Laura Ruohonen, Mervi Toivari, Merja Penttila
  • Method for producing terpenes
    Publication number: 20140045238
    Abstract: The present invention relates to a method for producing terpenes in fungi, wherein a terpene biosynthetic gene cluster having terpene biosynthetic genes and regulatory regions operably linked to said genes is activated. The invention relates also to a terpene biosynthetic gene cluster and regulatory regions of such terpene biosynthetic gene cluster usable is production of terpenes, use of regulator for regulating the terpene production and use of Aspergillus nidulans FGSC A4 for producing terpenes. The method of invention provides higher yields of enriched terpene product without essential amount of side-products.
    Type: Application
    Filed: November 14, 2011
    Publication date: February 13, 2014
    Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTT
    Inventors: Kirsi Bromann, Tiina Nakari-Setala, Laura Ruohonen, Mervi Toivari, Merja Penttila