Patents by Inventor Kirsi-Marja Oksman-Caldentey

Kirsi-Marja Oksman-Caldentey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterologous production of psilocybin
    Patent number: 11952580
    Abstract: A recombinant host cell is disclosed for producing psilocybin and related compounds, such as metabolic intermediates of the psilocybin biosynthesis. Also provided is a method of producing psilocybin and its synthesis intermediates and related compounds, such as metabolic intermediates of the psilocybin biosynthesis, in the host cell, as well as a production system for producing them.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: April 9, 2024
    Assignee: TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
    Inventors: Dominik Mojzita, Heiko Rischer, Anssi Rantasalo, Kirsi-Marja Oksman-Caldentey, Joosu Kuivanen
  • HETEROLOGOUS PRODUCTION OF PSILOCYBIN
    Publication number: 20210010015
    Abstract: A recombinant host cell is disclosed for producing psilocybin and related compounds, such as metabolic intermediates of the psilocybin biosynthesis. Also provided is a method of producing psilocybin and its synthesis intermediates and related compounds, such as metabolic intermediates of the psilocybin biosynthesis, in the host cell, as well as a production system for producing them.
    Type: Application
    Filed: March 11, 2019
    Publication date: January 14, 2021
    Inventors: Dominik MOJZITA, Heiko RISCHER, Anssi RANTASALO, Kirsi-Marja OKSMAN-CALDENTEY, Joosu KUIVANEN
  • Plant cell lines established from the medicinal plant veratrum californicum
    Publication number: 20090305338
    Abstract: The present invention relates to the field of plant secondary metabolites. More particularly plant cell lines are established from the medicinal plant Veratrum californicum. Said plant cell lines can be used for the production of cyclopamine and related steroid alkaloids and their precursors.
    Type: Application
    Filed: September 26, 2007
    Publication date: December 10, 2009
    Inventors: Anneli Ritala-Nurmi, Heiko Rischer, Kirsi-Marja Oksman-Caldentey, Ma Rui
  • Use of genes encoding membrane transporter pumps to stimulate the production of secondary metabolites in biological cells
    Patent number: 7622634
    Abstract: The invention relates to the field of secondary metabolite production in plants and plant cell cultures. More specifically, the invention relates to the use of transporters and more particularly ABC-transporters to enhance the production and/or secretion of secondary metabolites in plants and plant cell cultures.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: November 24, 2009
    Assignee: VTT Biotechnology
    Inventors: Alain Goossens, Dirk Gustaaf Inze, Kirsi-Marja Oksman-Caldentey, Into J. Laakso
  • Means and Methods to Enhance the Production of Vinblastine and Vincristine in Catharanthus Roseus
    Publication number: 20090165167
    Abstract: The present invention relates to the field of plant secondary metabolites, particularly terpenoid indole alkaloids. More particularly the present invention relates to the production of the anti-cancer metabolites vincristine and vinblastine. The invention provides novel polynucleotide sequences derived from Catharanthus roseus and the use of said polynucleotide sequences to stimulate the production of vinblastine and/or vincristine in plants of Catharanthus roseus and plant cell lines derived thereof. The invention further relates to recombinant plants, plant cells, tissue and organ cultures obtainable by the process of the invention.
    Type: Application
    Filed: September 14, 2006
    Publication date: June 25, 2009
    Inventors: Alain Goossens, Heiko Rischer, Dirk G. Inze, Matej Oresic, Kirsi-Marja Oksman-Caldentey
  • Genes and uses thereof to modulate secondary metabolite biosynthesis
    Publication number: 20060041962
    Abstract: The present invention relates to the use of a genome wide expression profiling technology in combination with the detection of the presence of secondary metabolites of interest to isolate genes that can be used to modulate the production of secondary metabolites in organisms and cell lines derived therefrom.
    Type: Application
    Filed: November 16, 2004
    Publication date: February 23, 2006
    Inventors: Dirk Inze, Alain Goossens, Kirsi-Marja Oksman-Caldentey, Suvi Hakkinen, Into Laakso