Abstract: Malaria is responsible for 1-2 million deaths and 300-500 million clinical cases annually and is an ever present problem for the military, tourists and business travelers. Mefloquine is known and used for malaria prophylaxis. However it is associated with neurological effects. The present invention is directed to providing new and novel quinoline analogs that are less neurotoxic than mefloquine without compromising efficacy. The present invention is also directed to the prevention and treatment of other microbial, parasitic, protozoan, bacterial and fungal diseases.

Abstract: A networked system with a product finder associated with an expert system is used to assist a shopper in making a product selection. A shopper interacts with the server through a browser over the network. The system can be connected to a retail server in such a way as to allow a shopper to complete a purchase. The expert system presents a series of questions to the shopper. By answering the questions, the shopper drills down through a hierarchy to arrive at a recommended product. Alternately, the shopper fills out a screen of data which is then used as a filter to identify an appropriate product.