Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Abstract: A computer-implemented system and method for reformatting and delivering emails as conversations. The computer-implemented method includes: synchronizing with an email service and receiving an email message via a data network; parsing content of the received email message to identify and suppress email content not related to conversational content and retaining the conversational content; reformatting the received email message to include the conversational content in a chat style format as an expressive conversation; making the expressive conversation available to a client email application; and presenting the expressive conversation to a user via the client email application.

Abstract: An imaging system for increasing image resolution is provided. In one embodiment, the system comprises a camera lens, beam splitters, color image sensors, multiple-DOF (degree of freedom) actuators, and a computational unit. One beam splitter receives light from the camera lens, and each color image sensor receives a split light beam from one of the beam splitters. The color image sensors are configured to individually sense a scene with different focus to yield captured images. Each actuator connects to an individual color image sensor for translating and rotating the individual color image sensor. The computational unit is configured to: compute a geometric transformation among the captured images so as to configure the actuators to align the color image sensors by performing translation and rotation on the color image sensors; and to perform luminance unification on the captured images to output a resultant image.

Abstract: Recombinant microorganisms comprising at least one exogenous nucleic acid sequence and capable of producing adipate semialdehyde are provided. Adipate semialdehyde may be produced in a synthesis pathway utilizing a single thiolase reaction. Adipate semialdehyde may also be produced from intermediates consisting of alpha, omega difunctional aliphatic organic molecules. Methods of using recombinant microorganisms to produce 6-aminocaproic acid, adipic acid, hexamethylenediamine and 1.6-hexanediol are also provided.

Abstract: Processes process for producing adipate or adipic acid using biological pathways and chemical catalyzes are disclosed. Homocitric acid may be a substrate in reaction pathways leading to adipic acid or a salt thereof.

Abstract: A chemical having the formula (S) 2-amino-6-hydroxypimelate. (S)-2-amino-6-hydroxypimelate can be made using a method comprising culturing a cell comprising an exogenous nucleic acid sequence encoding an enzyme that catalyzes the substrate to product conversion of (S)-2-amino-6-oxopimelate to (S)-2-amino-6-hydroxypimelate and separating the (S)-2-amino-6-hydroxypimelate. The cell may be a recombinant microorganism for producing aminocaproic acid or hexamethylenediamine from (S)-2-amino-6-hydroxypimelate comprising at least one exogenous nucleic acid sequence that expresses at least one polypeptide with substrate preference for homolysine, and amino acid decarboxylase with substrate preference for alpha-aminopimelate.

Abstract: Novel decorative products including interior home decorative products, garden ornaments, building decorative products and the like are disclosed in which the novel decorative products are characterized in having rigid shells of compacted fiber reinforced magnesium oxychloride composite, seam lines of below two millimeters and cores of which densities can be adjusted according to the preferred weight of the products during the product design stage. The aforesaid compacted fiber reinforced magnesium oxychloride composite is characterized in having compacted structures of F-5 MOC phase magnesium oxychloride. A method for producing the novel decorative products is also provided.

Abstract: A method for producing cis,trans- and trans,trans-isomers of muconate by providing cis,cis -muconate produced from a renewable carbon source through biocatalytic conversion; isomerizing cis,cis-muconate to cis,trans-muconate under reaction conditions in which substantially all of the cis,cis-muconate is isomerized to cis,trans -muconate; separating the cis,trans-muconate; and crystallizing the cis,trans-muconate. The cis,trans-isomer can be further isomerized to the trans,trans-isomer. In one example, the method includes culturing recombinant cells that express 3-dehydroshikimate dehydratase, protocatechuate decarboxylase and catechol 1,2-dioxygenase in a medium comprising the renewable carbon source and under conditions in which the renewable carbon source is converted to 3-dehydroshikimate by enzymes in the common pathway of aromatic amino acid biosynthesis of the cell, and the 3-dehydroshikimate is biocatalytically converted to cis,cis-muconate.

Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Abstract: A method of increasing the production a difunctional alkane in a microorganism that produces a difunctional alkane from alpha-keto acid by increasing the production of homocitrate in the cell relative to a wild-type or parent cell. The production of homocitrate may be obtained by engineering pathways that increase the production of alpha-ketoacid, such as alpha-ketoglutarate.

Abstract: A method for producing cis,trans- and trans,trans-isomers of muconate by providing cis,cis-muconate produced from a renewable carbon source through biocatalytic conversion; isomerizing cis,cis-muconate to cis,trans-muconate under reaction conditions in which substantially all of the cis,cis-muconate is isomerized to cis,trans-muconate; separating the cis,trans-muconate; and crystallizing the cis,trans-muconate. The cis,trans-isomer can be further isomerized to the trans,trans-isomer. In one example, the method includes culturing recombinant cells that express 3-dehydroshikimate dehydratase, protocatechuate decarboxylase and catechol 1,2-dioxygenase in a medium comprising the renewable carbon source and under conditions in which the renewable carbon source is converted to 3-dehydroshikimate by enzymes in the common pathway of aromatic amino acid biosynthesis of the cell, and the 3-dehydroshikimate is biocatalytically converted to cis,cis-muconate.

Abstract: In one embodiment, an advertisement is matched to subject matter in a portion of rich media content, such as a digital video, Flash™ animation, etc. For example, during the playing of rich media content, it may be determined by audio recognition techniques that the content's subject matter matches or correlates with an advertisement. Rendering preferences associated with the advertisement are then determined. The rendering preferences may be used to determine how the advertisement should be rendered (i.e., displayed in association with the content). The advertisement is then served to a device. The advertisement is served such that it can be rendered relative to a time that the portion of media is being displayed on the device.

Abstract: Novel decorative products including interior home decorative products, garden ornaments, building decorative products and the like are disclosed in which the novel decorative products are characterized in having rigid shells of compacted fiber reinforced magnesium oxychloride composite, seam lines of below two millimeters and cores of which densities can be adjusted according to the preferred weight of the products during the product design stage. The aforesaid compacted fiber reinforced magnesium oxychloride composite is characterized in having compacted structures of F-5 MOC phase magnesium oxychloride. A method for producing the novel decorative products is also provided.

Abstract: A current-feedback amplifier with at least one feed-forward capacitor at the input stage of the current-feedback amplifier is provided. In one embodiment, the current-feedback amplifier and feed-forward capacitor(s) are arranged as follows. The input stage includes two translinear loops, where each translinear loop includes a translinear element that is connected to the non-inverting input of the current-feedback amplifier. One feed-forward capacitor is in parallel with each translinear element that is connected to the non-inverting input of the current-feedback amplifier. In other embodiments, the feed forward capacitor(s) are arranged in a different manner.

Abstract: A moldable matrix comprises a mixture of magnesium chloride, magnesium oxide, sodium hexametaphosphate, and/or sodium pyrophosphate. The matrix can be used as an environmentally-friendly substitute to conventional construction material such as plastics and woods.

Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Abstract: The present invention is based on the discovery of a unique 14-gene molecular prognostic signature that is useful for predicting breast cancer metastasis. In particular, the present invention relates to methods and reagents for detecting and profiling the expression levels of these genes, and methods of using the expression level information in predicting risk of breast cancer metastasis.

Abstract: An area-efficient capacitor-free low-dropout regulator based on a current-feedback frequency compensation technique is disclosed. An implementation of a current feedback block with a single compensation capacitor is used to enable capacitance reduction. The resultant low-dropout regulator does not generally require an off-chip capacitor for stability and is particularly useful for system-on-chip applications.